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M2 polarization

Macrophage M1/M2 Polarization Dynamically Adapts to Changes in Cytokine Microenvironments in Cryptococcus neoformans Infection

Macrophage M1/M2 Polarization Dynamically Adapts to Changes in Cytokine Microenvironments in Cryptococcus neoformans Infection

... while M2 macrophages are not (7–9, 22, 30, ...from M2 to M1 and vice versa is ...or M2 polarization, respectively, as evidenced by uniform induction of the applicable marker genes ...initial ...

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Original Article The M2 polarization of macrophage induced by fractalkine in the endometriotic milieu enhances invasiveness of endometrial stromal cells

Original Article The M2 polarization of macrophage induced by fractalkine in the endometriotic milieu enhances invasiveness of endometrial stromal cells

... induce M2 polarization of macrophage with decreased expression of ...inducing M2 polarization of macrophage which in turn enhances invasiveness of ...

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TCF-4 Regulated lncRNA-XIST Promotes M2 Polarization Of Macrophages And Is Associated With Lung Cancer

<p>TCF-4 Regulated lncRNA-XIST Promotes M2 Polarization Of Macrophages And Is Associated With Lung Cancer</p>

... the M2 polarization of THP-1 macrophages induced by IL-4 when lncRNA XIST was knockdown, which may further note the importance of TCF-4 in M2 macrophages, as well as in the TAMs-induced cell prolif- ...

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Original Article Berberine improves metabolic syndrome insulin resistance by inducing macrophage M2 polarization

Original Article Berberine improves metabolic syndrome insulin resistance by inducing macrophage M2 polarization

... for the treatment of insulin resistance has been studied. Chang, et al. [15] showed that BBR improves insulin resistance in cardiomyocytes via activation of 5’-adenosine monophosphate- activated protein kinase. ...

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Malibatol A regulates microglia M1/M2 polarization in experimental stroke in a PPARγ-dependent manner

Malibatol A regulates microglia M1/M2 polarization in experimental stroke in a PPARγ-dependent manner

... M1/M2 polarization markers in the cortex of the mouse experimental stroke model and also unravel the potential mechanism with PPARγ activation and the underlying ...

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Melatonin-stimulated MSC-derived exosomes improve diabetic wound healing through regulating macrophage M1 and M2 polarization by targeting the PTEN/AKT pathway

Melatonin-stimulated MSC-derived exosomes improve diabetic wound healing through regulating macrophage M1 and M2 polarization by targeting the PTEN/AKT pathway

... macrophage polarization to alleviate islet dysfunction in type 2 diabetic mice ...M1 polarization and promoting M2 polarization to reduce ...of M2 polarization by MSC-derived ...

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Original Article Interleukin-22 promotes macrophage M2 polarization via STAT3 pathway

Original Article Interleukin-22 promotes macrophage M2 polarization via STAT3 pathway

... the polarization and function of M1 or M2 ...M2b polarization, partly through inducing TNF-α/ IL-1β secretion and subsequent NF-κB pathway ...the M2 switch [24]; whereas PPAR and PPAR [25] ...

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Nanotubular TiO2 regulates macrophage M2 polarization and increases macrophage secretion of VEGF to accelerate endothelialization via the ERK1/2 and PI3K/AKT pathways

Nanotubular TiO<sub>2</sub> regulates macrophage M2 polarization and increases macrophage secretion of VEGF to accelerate endothelialization via the ERK1/2 and PI3K/AKT pathways

... Notes: (A) seM of macrophages incubated for 3 days on different samples (cP, TNT20, TNT40, and TNT60). (B) confocal detection of the M1 marker protein cD86 after 48 hours of culture. (C) confocal detection of the ...

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Adipocyte secreted exosomal microRNA 34a inhibits M2 macrophage polarization to promote obesity induced adipose inflammation

Adipocyte secreted exosomal microRNA 34a inhibits M2 macrophage polarization to promote obesity induced adipose inflammation

... in polarization of adipose-resident macrophages from proinflammatory M1 to antiinflammatory M2 ...suppressing M2 polarization by repressing the expression of Krüppel-like factor 4 ...on ...

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TGF- induces M2-like macrophage polarization via SNAIL- mediated suppression of a pro-inflammatory phenotype

TGF- induces M2-like macrophage polarization via SNAIL- mediated suppression of a pro-inflammatory phenotype

... a M2-like phenotype characterized by up-regulation of the anti-inflammatory cytokine IL-10, and down-regulation of the pro-inflammatory cytokines TNF- α and ...caused M2-like differentiation by inhibiting ...

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miR-106b-5p Inhibits IRF1/IFN-&beta; Signaling to Promote M2 Macrophage Polarization of Glioblastoma

<p>miR-106b-5p Inhibits IRF1/IFN-&beta; Signaling to Promote M2 Macrophage Polarization of Glioblastoma</p>

... Previous studies have shown that IRF1 and IFN- β are two crucial molecules involved in the LPS and IFN- γ - initiated signaling pathway. They interact with each other, and participate in the IRF5-mediated regulation of ...

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Dual polarization of human alveolar macrophages progressively increases with smoking and COPD severity

Dual polarization of human alveolar macrophages progressively increases with smoking and COPD severity

... not M2 polarization, suggesting that acute tissue injury induces a prompt proinflammatory M1 phenotype ...M1 polarization is the finding that, upon smoking cessation, the percentage of AM expressing ...

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Lysyl tRNA synthetase–expressing colon spheroids induce M2 macrophage polarization to promote metastasis

Lysyl tRNA synthetase–expressing colon spheroids induce M2 macrophage polarization to promote metastasis

... cause M2 polarization of macro- ...or M2 macrophages were analyzed by real-time PCR to study how CM from HCT116 cancer spheroids with different KRS expres- sion levels affected ...CD206, M2 ...

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MFHAS1 promotes colorectal cancer progress by regulating polarization of tumor-associated macrophages via STAT6 signaling pathway

MFHAS1 promotes colorectal cancer progress by regulating polarization of tumor-associated macrophages via STAT6 signaling pathway

... Since M2 but not M1 macrophages exhibit protumoral properties, the lack of pro-CRC effects of MFHAS1-silenced macrophages was presumably attributed to inhibited M2 polarization of these ...

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Ovatodiolide suppresses colon tumorigenesis and prevents polarization of M2 tumor-associated macrophages through YAP oncogenic pathways

Ovatodiolide suppresses colon tumorigenesis and prevents polarization of M2 tumor-associated macrophages through YAP oncogenic pathways

... and M2 TAM ...Comparative M2 polarizing ability between THP-1 macrophages co-cultured with YAP1 wild-type (WT) and YAP1-knockeddown (KD) DLD-1 ...the M2-polarization process was significantly ...

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Original Article Effect of Sitagliptin on the anti-atherogenic M2 macrophage polarization

Original Article Effect of Sitagliptin on the anti-atherogenic M2 macrophage polarization

... in polarization of macrophages have not been well ...macrophage polarization towards M2 cells through acti- vating ...of M2 macrophage expression, in- cluding the scavenger receptor CD163 and ...

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Macrophage polarization in periodontal ligament stem cells enhanced periodontal regeneration

Macrophage polarization in periodontal ligament stem cells enhanced periodontal regeneration

... M1/M2 polarization of macrophages to adapt to extracellular ...M1/M2 polarization of macrophages participated in the tissue homeostasis and wound healing during periodontal ligament stem cell ...

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Anti-inflammatory signaling by mammary tumor cells mediates prometastatic macrophage polarization in an innovative intraductal mouse model for triple-negative breast cancer

Anti-inflammatory signaling by mammary tumor cells mediates prometastatic macrophage polarization in an innovative intraductal mouse model for triple-negative breast cancer

... or M2) [7 – ...a M2 macrophage population producing key mediators such as matrix metalloproteinases (including MMP-9) and vascular endothelial growth factor (VEGF) that stimulate break- down of the ...

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Effects of DC Stray Current on the Polarization Characteristics of X70 Steel

Effects of DC Stray Current on the Polarization Characteristics of X70 Steel

... Tafel extrapolation and three-parameter equation fitting methods are the conventional methods of data processing of Tafel polarization curves in the absence of DC current. Tafel extrapolation method is based on ...

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CTHRC1 in Ovarian Cancer Promotes M2-Like Polarization of Tumor-Associated Macrophages via Regulation of the STAT6 Signaling Pathway

<p>CTHRC1 in Ovarian Cancer Promotes M2-Like Polarization of Tumor-Associated Macrophages via Regulation of the STAT6 Signaling Pathway</p>

... and M2- like macrophages — with opposite ...as M2-like macro- phages, which generally promote tumor growth and ...the M2-like ...into M2-like TAMs activated by tumor stroma-derived ...

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