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Macrophage function

Identification of Ceruloplasmin as a Gene that Affects Susceptibility to Glomerulonephritis Through Macrophage Function

Identification of Ceruloplasmin as a Gene that Affects Susceptibility to Glomerulonephritis Through Macrophage Function

... properties, macrophage-derived ce- ruloplasmin contributes importantly to protection against inflammation and tissue injury in acute and chronic experi- mental colitis (Bakhautdin et ...M1-like macrophage ...

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Influenza Virus Overcomes Cellular Blocks To Productively Replicate, Impacting Macrophage Function

Influenza Virus Overcomes Cellular Blocks To Productively Replicate, Impacting Macrophage Function

... In complementary experiments, we introduced a point mutation in the VN/1203 HA that changed the pH of activation to be more acidic (29), significantly decreasing the percentage of nuclear NP. However, this virus ...

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Syncytium calcium signaling and macrophage function in the heart

Syncytium calcium signaling and macrophage function in the heart

... the macrophage differentiation and settlement in heart after MI, many gating strategies employed with com- bined different ...M2 macrophage [23], and CD45+CD11 b+F4/80+Ly6Clow for Resident cardiac ...

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Differential Macrophage Function in Brown Swiss and Holstein Friesian Cattle

Differential Macrophage Function in Brown Swiss and Holstein Friesian Cattle

... their function as antigen presenting cells, MØ constantly sam- ple the local environment and have antigen presenting capacity (Chesnut and Grey, 1985; Gordon, 1998; Gordon and Taylor, ...

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Oral contraceptives modify DNA methylation and monocyte-derived macrophage function

Oral contraceptives modify DNA methylation and monocyte-derived macrophage function

... Conclusions: OC use induced many changes in hematological and plasmatic markers, modifying hormonal levels, endothelial function, inflammation index and some redox state parameters, producing a perturbation of the ...

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Ablation of SP-A has a negative impact on the susceptibility of mice to Klebsiella pneumoniae infection after ozone exposure: sex differences

Ablation of SP-A has a negative impact on the susceptibility of mice to Klebsiella pneumoniae infection after ozone exposure: sex differences

... phagocytic function in WT mice after ...alveolar macrophage function in response to ozone exposure and ...alveolar macrophage phago- cytic function of ...mice function sub-opti- ...

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Glucocorticoid mediated repression of cytokine gene transcription in human arteritis SCID chimeras

Glucocorticoid mediated repression of cytokine gene transcription in human arteritis SCID chimeras

... the function of the inflammatory infiltrate or why the disease persists subclinically despite chronic ...and macrophage function as indicated by the reduced tissue concentrations of IL-2, IL-1beta, ...

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Early bacterial clearance from murine lungs  Species dependent phagocyte response

Early bacterial clearance from murine lungs Species dependent phagocyte response

... Using this model, the clearance of intrapulmonary bacteria in granulocytopenic animals can be attributed predominantly to alveolar macrophage function and mucociliary clearance, and an a[r] ...

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Comparison of fluticasone propionate and budesonide on COPD macrophage and neutrophil function

Comparison of fluticasone propionate and budesonide on COPD macrophage and neutrophil function

... In order to determine potential mechanisms of CS action on macrophage function, scavenger-receptor expression was analyzed. A variety of receptors were analyzed in this study to reflect the diverse array of ...

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The IL 21 receptor augments Th2 effector function and alternative macrophage activation

The IL 21 receptor augments Th2 effector function and alternative macrophage activation

... modulating macrophage function, because our in vivo data showed a marked reduction in several genes that have been associated with the “alternatively activated” phenotype (33, ...because ...

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Identification of the microRNA networks contributing to macrophage differentiation and function

Identification of the microRNA networks contributing to macrophage differentiation and function

... and function is beginning to emerge [23- 26], however the specific miRNA networks regulating translation during differentiation of specific subsets of leukocytes is yet to be fully ...monocyte/macrophage ...

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Interferon-γ acts as a regulator in the trade-off between phagocytosis and production performance in dwarf chickens

Interferon-γ acts as a regulator in the trade-off between phagocytosis and production performance in dwarf chickens

... and macrophage function that enhances the respiratory burst via up-regulating the class II major histocompatibility complex and suppresses the capacity of nonopsonic receptors on the surface of macrophages ...

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EGFR regulates macrophage activation and function in bacterial infection

EGFR regulates macrophage activation and function in bacterial infection

... regulates macrophage function, but its role in bacterial infection has not been ...of macrophage EGFR signaling during infection with Helicobacter pylori, a bacterial pathogen that causes persistent ...

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Atherosclerosis: pathogenesis and increased occurrence in individuals with HIV and Mycobacterium tuberculosis infection

Atherosclerosis: pathogenesis and increased occurrence in individuals with HIV and <em>Mycobacterium tuberculosis</em> infection

... immune function that occurs with low GSH in the macrophage may also increase susceptibility to infection with ...of macrophage function related to the ingestion of ox-LDL and the decreased ...

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The function of heme regulated eIF2α kinase in murine iron homeostasis and macrophage maturation

The function of heme regulated eIF2α kinase in murine iron homeostasis and macrophage maturation

... Since HRI plays such an important role in the production of hemoglobin and formation of the rbc that contain nearly 70% of the total body iron, it may also play an important role in system- ic and cellular iron ...

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CD163+ macrophages promote angiogenesis and vascular permeability accompanied by inflammation in atherosclerosis

CD163+ macrophages promote angiogenesis and vascular permeability accompanied by inflammation in atherosclerosis

... thrombin generation with consequent changes in cellular func- tions induced by protease-activated receptor action. Nonetheless, the in vitro demonstrations of these effects in cultured endothelial cells under normoxic ...

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Gliotoxin Suppresses Macrophage Immune Function by Subverting Phosphatidylinositol 3,4,5 Trisphosphate Homeostasis

Gliotoxin Suppresses Macrophage Immune Function by Subverting Phosphatidylinositol 3,4,5 Trisphosphate Homeostasis

... oxidase function in neutrophils (14, 52), pre- cludes the cytotoxic properties of T lymphocytes (13), and pre- vents NF-␬B-dependent transcription of cytokines in both B and T cells ...

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Original Article Effect of granulocyte-macrophage colony stimulating factor treatment on myocardial perfusion and heart function in patients with coronary artery disease

Original Article Effect of granulocyte-macrophage colony stimulating factor treatment on myocardial perfusion and heart function in patients with coronary artery disease

... cardiac function that were assessed by semi-quantitative perfusion score (QGS) and left ventricular ejection fraction (LVEF) under the emission computed to ...

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Fibroblast biology Effector signals released by the synovial fibroblast in arthritis

Fibroblast biology Effector signals released by the synovial fibroblast in arthritis

... chemokines macrophage chemotactic protein (MCP)-1 and macro- phage inflammatory protein (MIP)-1α that are primarily responsible for attracting monocytes into the synovium [16 • ...

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Effect of hematopoietic growth factors on human blood monocytes/macrophages in in vitro culture.

Effect of hematopoietic growth factors on human blood monocytes/macrophages in in vitro culture.

... The addition of macrophage CSF, granulocyte-macrophage CSF, and granulocyte CSF and interleukin-6 and interleukin-3 growth factors to monocyte/macrophage cultures induced morphological c[r] ...

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