Macrophage polarization
AGEs Induced Autophagy Impairs Cutaneous Wound Healing via Stimulating Macrophage Polarization to M1 in Diabetes
... stimulated macrophage polarization to M1 with gene expressions of il-1β, il-6, inos, tnf-α and high population of CD11c cells, but no changes of M2 ...M2 polarization 23 ...
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Biological Effects of Nanoparticles on Macrophage Polarization in the Tumor Microenvironment
... The macrophage polarization effects of carbon nanospheres (CNS) have also been ...on macrophage polarization ...M1-like polarization state. In a macrophage-cancer cell co-culture ...
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First case report of M1 macrophage polarization in an untreated symptomatic patient with toxoplasmosis
... suppresses the production of specific IgM and IgG in mice [14] and decreases the production of IgG in pregnant women [15]. Whether anti-parasitic therapy affects macro- phage polarization remains to be ...
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Epigenetic regulation of macrophage polarization and inflammation by DNA methylation in obesity
... M2 macrophage activation. The induction of M2 macrophage polarization is mediated by STAT6 (2), while the nuclear receptors PPARγ and PPARδ also play important roles in this process ...
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Biomaterial based modulation of macrophage polarization: A review and suggested design principles
... on macrophage polarization and identified a cell shape-mediated mechanism for this ...M2 polarization [39], suggesting that in addition to directing polarization, biophysical cues directly ...
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Parasitic antigens alter macrophage polarization during Schistosoma japonicum infection in mice
... M2 polarization have been shown to inhibit M1 polarization and the production of NO by M1 macrophages ...peritoneal macrophage polarization during schistosome ...
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Integrin mediated interactions control macrophage polarization in 3D hydrogels
... α2β1-mediated macrophage polarization was not restricted to the THP-1 monocytic cell line, we also seeded human primary monocytes on plates coated with integrin α2β1 peptide (the type I collagen α1(I)-CB3 ...
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<p>Myelin basic protein charge isomers change macrophage polarization</p>
... Materials and methods: MBP was isolated and purified from bovine brain white matter. RAW 264.7 macrophages were cultured in DMEM supplemented with heat-inactivated fetal bovine serum. For evaluation of macrophage ...
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Nanostructured titanium regulates osseointegration via influencing macrophage polarization in the osteogenic environment
... Figure 9 Schematic diagram of the effects of nanotopography-mediated macrophage polarization on the osteogenic differentiation of BMSCs and osseointegration. Notes: Once the titanium implants with nanotubes ...
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Krüppel like factor 4 regulates macrophage polarization
... two macrophage subsets, termed M1 and M2, are involved in inflammation and host ...of macrophage polarization. Macrophage KLF4 expression was robustly induced in M2 mac- rophages and strongly ...
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Original Article Effect of Sitagliptin on the anti-atherogenic M2 macrophage polarization
... in polarization of macrophages have not been well ...on macrophage po- ...induce macrophage polarization towards M2 cells through acti- vating ...M2 macrophage expression, in- cluding ...
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Ginseng-derived nanoparticles alter macrophage polarization to inhibit melanoma growth
... M1-like macrophage polarization via Toll-like receptor (TLR)-4/myeloid differentiation antigen 88 (MyD88) signalling pathway and enhance production of total reactive oxygen species (ROS) to induce apoptosis ...
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Modulation of Macrophage Polarization for Bone Tissue Engineering Applications
... the polarization of macrophage phenotype towards the anti-inflammatory M2, rather than the inflammatory M1 phenotype, promotes ...of macrophage polarization, especially towards M2 phenotype, ...
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Macrophage polarization in periodontal ligament stem cells enhanced periodontal regeneration
... Results: Elevated bone volume and average thickness of bone trabecular was observed in the PDLSC-treated group by micro-computed tomography on day 21. In addition, enhanced periodontal regeneration was observed in the ...
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Zoledronic acid exacerbates inflammation through M1 macrophage polarization
... Background: Zoledronic acid (Zol), one of the bisphosphonates, is frequently utilized for the treatment of osteoporosis and bone metastasis. However, the onset of medication-related osteonecrosis of the jaw (MRONJ) ...
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TGF- induces M2-like macrophage polarization via SNAIL- mediated suppression of a pro-inflammatory phenotype
... M1 polarization through up-regulation of pro-inflammatory cytokines and abolished TGF-β-mediated M2-polarization of THP-1 ...skews macrophage polarization towards a M2-like phenotype via SNAIL ...
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Cantharidin Exerts Anti-Hepatocellular Carcinoma by Mir-214 Modulating Macrophage Polarization
... The effect of NCTD on H22 cells viability It has been reported that NCTD is involved in inhibiting the proliferation of HCC cells [28]. There- fore, the potential effects of NCTD on H22 cell viabil- ity were evaluated ...
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Metabolic reprograming in macrophage polarization
... macrophage biology that has only started to develop more recently. Although we are still very much in the dark regarding our under- standing of the metabolic molecular events driving macrophage ...
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Macrophage Polarization in Inflammatory Diseases
... of macrophage polarization, grow- ing evidences support that M1 phenotype macro- phages contribute to the development of ...of macrophage po- larization might provide a new way for the resolution ...
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Btk regulates macrophage polarization in response to lipopolysaccharide
... To date there has been no direct evidence supporting a role for Btk in macrophage polarization and reports of Btks contribution to inflammation have been controversial. Several studies have suggested that ...
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