Macrophage recruitment
Adrenergic regulation of monocyte chemotactic protein 1 leads to enhanced macrophage recruitment and ovarian carcinoma growth
... monocyte/macrophage recruitment while undergoing sustained adrenergic signaling, we analyzed chemokine/cytokine changes using a cytokine/chemokine panel generated from SKOV3ip1 cells treated with ...
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Nod2 sensing of lysozyme digested peptidoglycan promotes macrophage recruitment and clearance of S pneumoniae colonization in mice
... the recruitment of monocytes/macrophages required their expression of the chemokine receptor CCR2 and correlated with expression of the CCR2 ligand ...monocyte/macrophage recruitment were defi- cient ...
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VEGF A stimulates lymphangiogenesis and hemangiogenesis in inflammatory neovascularization via macrophage recruitment
... VEGF-A–mediated recruitment of inflammatory cells by VEGFR1 ligation is an important step in the initiation of the lym- phangiogenic response in ...inhibited recruitment of inflammatory cells into the ...
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Increased B3GALNT2 in hepatocellular carcinoma promotes macrophage recruitment via reducing acetoacetate secretion and elevating MIF activity
... Macrophage migration inhibitory factor (MIF) is a pro- inflammatory cytokine with tautomerase activity and is usually released to the extracellular matrix [28, 29]. Des- pite its inhibition on random migration, ...
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Ninichuk, Volha (2008): The role of chemokine receptor CCR1-dependent macrophage recruitment for the progression of chronic kidney disease in murine Alport syndrome or type 2 diabetes. Dissertation, LMU München: Medizinische Fakultät
... such as LPS, peptidoglycanes, and unmethylated CpG-DNA (112). It has been found that injection of unmethylated CpG-DNA into mice with otherwise self-limiting immune complex glomerulonephritis resulted in progression ...
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Schwann cell–derived periostin promotes autoimmune peripheral polyneuropathy via macrophage recruitment
... cell recruitment to sites of inflam- mation in spinal cord injury and glioblastoma (20, 23, ...the recruitment of immune cells to the sciatic nerve during ...
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Leukocyte TLR5 deficiency inhibits atherosclerosis by reduced macrophage recruitment and defective T-cell responsiveness
... eBioscience). The ImmPRESS HRP anti-Rat IgG, Mouse adsorbed (Peroxidase) Polymer Detection Kit (Vector, Burlingame, CA, USA) was used as a secondary antibody and DAB (Sigma, St. Louis, MO, USA) as an enzyme substrate. ...
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LKB1 loss promotes endometrial cancer progression via CCL2 dependent macrophage recruitment
... (human macrophage marker), and ...the macrophage-specific scavenging receptor CD163 gave virtually superimposable patterns of expression and staining scores as CD68, further validating the use of CD68 as a ...
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Leukotriene B4 promotes neovascularization and macrophage recruitment in murine wet-type AMD models
... E–K). We also found that BLT1 was only induced during M2 polarization of primary mouse macrophages (Figure 5, A and B) and mouse (Figure 5C) or human (Figure 5D) macrophage cell lines. Preliminary experiments with ...
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CD44 is a macrophage binding site for Mycobacterium tuberculosis that mediates macrophage recruitment and protective immunity against tuberculosis
... Cell migration and phagocytosis are both critically dependent on cytoskeletal rearrangements and are important for resistance against tuberculosis. Since CD44 is an adhesion molecule involved in inflamma- tory processes ...
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Interleukin-34 promotes tumor progression and metastatic process in osteosarcoma through induction of angiogenesis and macrophage recruitment
... the Macrophage)Colony Stimulating Factor (M)CSF), a cytokine required for the survival and differentiation of mononuclear phagocytic cell lines derived from monocytes such as macrophages and dendritic cells ...
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Mo-derived perivascular macrophage recruitment protects against endothelial cell death in retinal vein occlusion
... leukocyte recruitment to an in- jured tissue [19]), CD11b (an integrin that is more strongly expressed in Mo than MCs; ...the recruitment and infiltration of Mo-derived ...
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Mesenchymal stem cells and macrophages interact through IL-6 to promote inflammatory breast cancer in pre-clinical models
... Importantly since IBC is characterized by rapid skin involvement, the reduction we saw in MSC induced skin invasion is noteworthy. These results suggest that the induction of the IBC phenotype with the addition of MSC ...
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Inflammatory macrophage migration requires MMP 9 activation by plasminogen in mice
... cell recruitment was investigated in 2 models: thioglycollate-induced peritonitis and AAA, an atherosclerotic and inflammatory ...phage recruitment and this role is mediated through activation of ...reduced ...
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Frontline Science: antagonism between regular and atypical Cxcr3 receptors regulates macrophage migration during infection and injury in zebrafish
... enhanced recruitment in ...amplified macrophage-mediated dissemination of bacteria that is facilitated by the higher speed of migrating macrophages and favors the formation of secondary gran- ...enhanced ...
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Cellular effectors mediating Th17 dependent clearance of pneumococcal colonization in mice
... Accelerated clearance in the secondary pneumococcal challenge is associated with enhanced cellular responses. Comparisons of the time course of (A) the density of P1121 colonization, (B) neutrophil recruitment, ...
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Targets for medical therapy to limit abdominal aortic aneurysm progression
... Atorvastatin has been reported to prevent AAA development by suppressing macrophage recruitment via inhibition of MCP-1, MMP-12 and ICAM-1 but not MMP-9 expression in an elastase-induced[r] ...
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microRNA-26a suppresses recruitment of macrophages by down-regulating macrophage colony-stimulating factor expression through the PI3K/Akt pathway in hepatocellular carcinoma
... been found to be associated with higher histological tumor grading, more frequent metastases, and poor prognosis in many cancer types, including papillary renal cell car- cinoma, serous and mucinous ovarian epithelial ...
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The Role of Cytosolic Access in Streptococcus Pneumoniae Nasopharyngeal Colonization
... the macrophage undergoes a pro-inflammatory cell ...the macrophage results in the release of IL-1β and sensing of IL-1 family cytokines is required for successful macrophage recruitment and ...
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Overexpression of complement component C5a accelerates the development of atherosclerosis in ApoE-knockout mice
... prominent macrophage chemotaxis of recombinant mouse C5a and cell culture supernatant of HEK293 cells treated with 100:1 MOI Ad- C5a for 24 hr (Figure 3C, ...during macrophage chemotaxis. The ...
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