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Macrophages and Monocytes

Infection and Functional Modulation of Human Monocytes and Macrophages by Varicella-Zoster Virus

Infection and Functional Modulation of Human Monocytes and Macrophages by Varicella-Zoster Virus

... infected monocytes did not remain viable during M-CSF differentiation, we sought to determine whether monocytes that had already differentiated to become M-M ␸ could be infected with ...derived ...

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TIE2-expressing monocytes/macrophages regulate revascularization of the ischemic limb

TIE2-expressing monocytes/macrophages regulate revascularization of the ischemic limb

... TIE2-expressing monocytes do not express the chemokine (C-C motif) receptor 2 (CCR2) and, rather than responding to CCL2 (formerly MCP-1), are recruited to sites of active neovascular- ization in close proximity ...

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Inflammatory Ly6Chi monocytes and their conversion to M2 macrophages drive atherosclerosis regression

Inflammatory Ly6Chi monocytes and their conversion to M2 macrophages drive atherosclerosis regression

... phage M2 characteristics, this does not definitely establish a direct link between these two findings. To demonstrate, using multiple approaches, that recipient mouse monocytes are indeed the source of M2 ...

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Activation of Terminally Differentiated Human Monocytes/Macrophages by Dengue Virus: Productive Infection, Hierarchical Production of Innate Cytokines and Chemokines, and the Synergistic Effect of Lipopolysaccharide

Activation of Terminally Differentiated Human Monocytes/Macrophages by Dengue Virus: Productive Infection, Hierarchical Production of Innate Cytokines and Chemokines, and the Synergistic Effect of Lipopolysaccharide

... Dengue virus (DV) primarily infects blood monocytes (MO) and tissue macrophages (M ␾ ). We have shown in the present study that DV can productively infect primary human MO/M ␾ regardless of the stage of ...

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Human monocytes and macrophages differ in their mechanisms of adaptation to hypoxia

Human monocytes and macrophages differ in their mechanisms of adaptation to hypoxia

... hyperproliferation. Monocytes migrate towards inflamed areas and differentiate into ...human monocytes is not yet ...in monocytes and macrophages, but also considered alternative pathways ...

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Thrombospondin binds to monocytes macrophages and mediates platelet monocyte adhesion

Thrombospondin binds to monocytes macrophages and mediates platelet monocyte adhesion

... including monocytes and ...peritoneal macrophages and to cells of the monocyte-like human cell line U937 with dissociation constants of ...blood monocytes. Using a sensitive rosetting assay, we found ...

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RIP140 in monocytes/macrophages regulates osteoclast differentiation and bone homeostasis

RIP140 in monocytes/macrophages regulates osteoclast differentiation and bone homeostasis

... Loss of osteoclast precursor RIP140 in vivo results in decreased cancellous volume. Given RIP140’s early expres- sion and biological activity in the monocyte-macrophage lineage, and that osteoclasts differentiate from ...

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Molecular mechanisms of neuroinvasion by monocytes macrophages in HIV 1 infection

Molecular mechanisms of neuroinvasion by monocytes macrophages in HIV 1 infection

... of monocytes and macrophages into the central nervous ...activated monocytes are the preferential targets for such ...positive monocytes are the main reservoir of monocyte/macrophage-harbored ...

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Protein energy malnutrition increases arginase activity in monocytes and macrophages

Protein energy malnutrition increases arginase activity in monocytes and macrophages

... that monocytes and macrophages are significantly increased in the bone marrow and blood of mice fed on a protein low ...derived macrophages isolated from malnourished mice to phagocytose particles, ...

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Harnessing the early post-injury inflammatory responses for cardiac regeneration

Harnessing the early post-injury inflammatory responses for cardiac regeneration

... recruited monocytes have been considered as a suitable therapy to prevent further weakening of the myocardium after ...by macrophages, is an essential com- ponent of tissue regeneration [7, ...

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Cloning, Expression, and Functional Analyses of MHC Class II A in Ayu, Plecoglossus altivelis

Cloning, Expression, and Functional Analyses of MHC Class II A in Ayu, Plecoglossus altivelis

... The MHC (major histocompatibility complex) class II family plays a major role in vertebrate immune systems and is normally found only on antigen-presenting cells. In this study, we identified the gene encoding the α ...

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An augmented passive immunotherapy to treat pneumococcal diseases

An augmented passive immunotherapy to treat pneumococcal diseases

... blood monocytes expressing significantly higher FcγR than in the control ...recruited monocytes/macrophages was detected in the lungs but their FcγR expression was similar to control ...of ...

255

Rhinovirus Replication in Human Macrophages Induces NF-κB-Dependent Tumor Necrosis Factor Alpha Production

Rhinovirus Replication in Human Macrophages Induces NF-κB-Dependent Tumor Necrosis Factor Alpha Production

... Lung macrophages (M ␾ ) are an important source for TNF- ␣ , are the most numerous cells in the airway lumen, and are quickly recruited during inflammatory processes of the lung ...cells, monocytes, or M ␾ ...

11

Role of glycogen synthase kinase-3 beta in the inflammatory response caused by bacterial pathogens

Role of glycogen synthase kinase-3 beta in the inflammatory response caused by bacterial pathogens

... primarily macrophages, dendritic cells, natural killer cells, and mast ...neutrophils, monocytes that differentiate into macrophages at the site of inflammation, and dendritic ...inflammation. ...

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C5a and its receptors in human anti neutrophil cytoplasmic antibody (ANCA) associated vasculitis

C5a and its receptors in human anti neutrophil cytoplasmic antibody (ANCA) associated vasculitis

... Results: The level of plasma C5a was significantly higher in patients with AAV in the active phase than that in patients in remission, that in patients with LN, and that in normal controls. The urinary C5a level was ...

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Innate immune cell–epithelial crosstalk during wound repair

Innate immune cell–epithelial crosstalk during wound repair

... M2 macrophages are induced by IL-4/IL-13 as well as IL-10. M2 macrophages release antiinflammatory/pro- repair molecules including TGF-β, IL-10, and SPMs such as mares- ins, resolvins, and protectins (see ...

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Functional variations of the TLR4 gene in association with chronic obstructive pulmonary disease and pulmonary tuberculosis

Functional variations of the TLR4 gene in association with chronic obstructive pulmonary disease and pulmonary tuberculosis

... of monocytes and macrophages and transmits activation signals after lipopolysaccharide (LPS) recognition, induces the expression of proinflam- matory cytokines, such as IL-1, myeloid differentiation factor ...

8

Effects of chalcone derivatives on players of the immune system

Effects of chalcone derivatives on players of the immune system

... in monocytes/macrophages Chalcone derivatives may perform potential anti-inflammatory activity in monocytes and ...264.7 macrophages and suggested that this compound could inhibit the ...

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Transduction of Nondividing Human Macrophages with Gammaretrovirus-Derived Vectors

Transduction of Nondividing Human Macrophages with Gammaretrovirus-Derived Vectors

... the macrophages’ susceptibility to retroviral infection, we hypoth- esized that the same could be true during monocyte-to-mac- rophage ...5. Monocytes transduced at that time were refractory to retroviral ...

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Discrepancy in Microglia and Peripheral Monocytic Cells - A scope in the Pathophysiology of Psychiatric maladies

Discrepancy in Microglia and Peripheral Monocytic Cells - A scope in the Pathophysiology of Psychiatric maladies

... conditions, monocytes are initiated from peripheral blood into the brain, where they collaborate with microglia in immune responses ...Peripheral monocytes have the capability to set apart into ...

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