major basic protein
Comparative properties of the Charcot Leyden crystal protein and the major basic protein from human eosinophils
... a protein, the major basic protein (MBP), which accounts for more than half of the total granule protein, has a high content of arginine, and displays a remarkable tendency to form ...
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In vivo neutralization of eosinophil derived major basic protein inhibits antigen induced bronchial hyperreactivity in sensitized guinea pigs
... eosinophil-derived major basic protein (MBP) Ig on antigen-induced bronchial hyperreactivity to inhaled acetylcholine in aerosol-sensitized guinea ...
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Markers of atopic dermatitis, allergic rhinitis and bronchial asthma in pediatric patients: correlation with filaggrin, eosinophil major basic protein and immunoglobulin E
... Eosinophils are well known for their vital role in aller- gic inflammatory processes and the eosinophil major basic protein is the most abundant constituent of the eosinophil secondary granules [24]. ...
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Pretreatment with antibody to eosinophil major basic protein prevents hyperresponsiveness by protecting neuronal M2 muscarinic receptors in antigen challenged guinea pigs
... eosinophil major basic protein was used to determine whether M2 muscarinic receptor dysfunction, and the subsequent hyperresponsiveness, are due to antagonism of the M2 receptor by eosinophil ...
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Acidic polyamino acids inhibit human eosinophil granule major basic protein toxicity Evidence of a functional role for ProMBP
... Eosinophil granule major basic protein (MBP), a potent toxin for helminths and mammalian cells in vitro, is a single polypeptide chain rich in arginine. MBP has been localized on damaged helminths ...
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Human eosinophil granule major basic protein and synthetic polycations induce airway hyperresponsiveness in vivo dependent on bradykinin generation
... In the current series of experiments we investigated the role of bradykinin in airway hyperresponsiveness induced by human eosinophil-granule major basic protein (MBP). Bronchoalveolar lavage was ...
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Human eosinophil major basic protein induces airway constriction and airway hyperresponsiveness in primates
... As a result of these findings we reasoned that toxic cationic eosinophil granule proteins, including the major basic protein MBP.' eosinophil cationic protein ECP, eosinophil peroxidase [r] ...
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Human eosinophil major basic protein is an endogenous allosteric antagonist at the inhibitory muscarinic M2 receptor
... eosinophil major basic protein (MBP) as well as other eosinophil proteins, on binding of [3H]N-methyl-scopolamine ([3H]NMS: 1 x 10(-10) M) to muscarinic M2 receptors in heart membranes and M3 ...
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Elevated serum levels of the eosinophil granule major basic protein in patients with eosinophilia
... The results indicate that eosinophil granule proteins circulate in blood covalently bound to serum proteins, and that elevated concentrations of serum MBP are present in some diseases as[r] ...
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Systemic Vasculitis Associated With Eosinophilia and Marked Degranulation of Tissue Eosinophils
... of lung, skin, parotid gland, and trachea showed eosinophilic infiltration and striking deposition of major basic protein in association with tissue.. damage, a finding that is in keepin[r] ...
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The major vault protein is related to the toxic anion resistance protein (TelA) family
... binding protein TIA-1, a robust marker of mammalian stress granules (Kedersha et ...a protein implicated in translational regulation, RNA processing and RNA transport (Dreyfuss et ...binding protein, ...
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Rotavirus Nonstructural Protein NSP5 Interacts with Major Core Protein VP2
... in insect cells. In the absence of infection with the NSP5- expressing baculovirus, VP2 was not detected (lanes 1 and 4). NSP5 modifies the subcellular distribution of VP2. In rota- virus-infected cells, NSP5 and VP2 are ...
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Composition of the antigenic material removed from Campylobacter jejuni by heat
... One of the major bands corresponded to the major outer membrane protein, as determined by comparison with an outer membrane protein preparation by sodium dodecyl sulfate-polyacrylamide g[r] ...
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Treatment of experimental encephalomyelitis with a novel chimeric fusion protein of myelin basic protein and proteolipid protein
... two major proteins of the myelin sheath, myelin basic protein (MBP) and proteolipid protein ...tolerogenic protein for the therapy of patients with MS, we have produced a protein ...
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A Validated Set of Fluorescent Protein Based Markers for Major Organelles in Yeast (Saccharomyces cerevisiae)
... a basic scheme of internal organization featuring membrane-based ...and protein trafficking. One major limitation of this approach is that the fusion of an FP to a target protein can and often ...
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Essays on Electoral Accountability and Equalization Transfer under a Decentralized Context: The Case of Peruvian Municipalities
... the Basic Psychological Needs Scale (Deci & Ryan, 2001) (see Appendix ...whole Basic Psychological Needs Scale, including the Autonomy subscale (Simoes & Alarcao, ...
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Novel variants of the newly emerged Anaplasma capra from Korean water deer (Hydropotes inermis argyropus) in South Korea
... heat-shock protein (groEL), major sur- face protein 2 (msp2) and major surface protein 4 (msp4) genes using the maximum likelihood (ML) method implemented in MEGA7 ...
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The varicella-zoster virus immediate-early protein IE62 is a major component of virus particles.
... A major transcriptional regulatory protein ICP4 of herpes simplex virus type 1 is associated with purified virions.. Association of a major transcriptional regulatory protein, ICP4, of h[r] ...
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Synthesis of the Major Bacteriophage f1 Coat Protein
... They also indicate the fd-type phage DNA replication, which is defective in cells infected by amber mutants in gene II 6, is necessary for normal levels of major fd-type phage coat prote[r] ...
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Comparison of Two Human Papovaviruses with Simian Virus 40 by Structural Protein and Antigenic Analysis
... The significant observation from these data is that the major protein of BK virus is approximately 3,000 to 5,000 daltons lighter than the major protein of SV40 or DAR virus, whereas the[r] ...
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