Malignant Glioma
Measurement of Tumor “Size” in Recurrent Malignant Glioma: 1D, 2D, or 3D?
... high-grade malignant glioma) are the most common primary brain tumors occurring in adulthood, and they are among the most lethal and difficult to treat forms of ...
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Pseudo-Progression Phenomenon During Temozolomide Combination Chemoradiotherapy for Malignant Glioma
... with malignant glioma treated with TMZ combination CRT (TMZ: 75 mg/day, RT: 60Gy in 30 fraction) followed by adjuvant TMZ (150 mg/day, Day 1-5, every 28 days) were ...3 glioma (anaplastic ...
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Treating malignant glioma in Chinese patients: update on temozolomide
... of malignant glioma and reflects multiple mechanisms, includ- ing molecular resistance to DNA damage and apoptosis, attenuation of cytotoxicity by the microenvironment, and our limited ability to deliver ...
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Karenitecin (bnp1350) and flavopridol as radiosensitizers in malignant glioma
... of malignant glioma patients highlights the need to develop low toxicity, tumor specific agents with the ability to synergize with proven efficacious treatment modalities, ...the glioma cell lines ...
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Drug-Loaded Nanoparticle Systems And Adult Stem Cells: A Potential Marriage For The Treatment Of Malignant Glioma?
... in malignant glioma research, only modest progress has been achieved in improving patient prognosis and quality of ...eradicate glioma infiltration and target distant tumor ...
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Reversing chemoresistance of malignant glioma stem cells using gold nanoparticles
... Cancer cells are very complex biological structures that per- form a variety of functions, ranging from invasion or metasta- sis to elimination of anticancer drugs from the cell membrane. Although the exact mechanisms ...
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Cytotoxicity induced by carbon nanotubes in experimental malignant glioma
... Abstract: Despite multiple advances in the diagnosis of brain tumors, there is no effective treatment for glioblastoma. Multiwalled carbon nanotubes (MWCNTs), which were previously used as a diagnostic and drug delivery ...
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Glioma Stem Cell Targeted Dendritic Cells as a Tumor Vaccine Against Malignant Glioma
... cure malignant glioma by using glioma stem cell-targeted dendritic cells as a tumor ...of glioma stem cells was a potent way to induce specific cytotoxic T lymphocytes and anti-tumor ...from ...
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Regulatory landscape and clinical implication of MBD3 in human malignant glioma
... aberration has been uncovered as a driving force in a variety of human diseases, its mechanistic relation to malignant glioma has been less explored. As a core epigenetic modulator, DNA methylation (mainly ...
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Temozolomide in malignant glioma
... Abstract: Glioblastoma multiforme WHO grade IV (GBM) is the most aggressive malignant glioma and the most frequent primary tumor of the central nervous system. The median survival of newly diagnosed GBM ...
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Antitumor effect of a new nano-vector with miRNA-135a on malignant glioma
... and malignant glioma cells ...with malignant glioma cell C6 and normal astrocytes in vitro and showed good biocompatibility evaluated by CCK8 ...of glioma confirmed by MRI and ...
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A peptide-mediated targeting gene delivery system for malignant glioma cells
... Abstract: Glioblastoma multiforme (GBM) is the most common and malignant glioma. Although there has been considerable progress in treatment strategies, the prognosis of many patients with GBM remains poor. ...
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<p>Preclinical And Clinical Development Of Oncolytic Adenovirus For The Treatment Of Malignant Glioma</p>
... of glioma; mesenchymal stem cell MSC-Delta24-RGD, 68 and MSC-ICOVIR17, 36 MSC-CRAd-CXCR4-5/3, 69 neural stem cells (NSC)-CRAd-survivin-pk7 69–72 demonstrated anti- glioma ...of malignant ...
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Protooncogene bcl 2 gene transfer abrogates Fas/APO 1 antibody mediated apoptosis of human malignant glioma cells and confers resistance to chemotherapeutic drugs and therapeutic irradiation
... the glioma cell lines to the cytokines, IFN gamma and TNF alpha, which sensitize for Fas/APO-1-dependent killing, partially overcame bcl-2-mediated rescue from apoptosis, suggesting that multimodality ...
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Plexin-B2 promotes invasive growth of malignant glioma
... in glioma growth and invasion, because it was originally cloned as a gene highly upregulated in malignant brain tumors ...of glioma patient samples identified Plexin-B2 as a potential biomarker for ...
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Original Article Podoplanin increases migration and angiogenesis in malignant glioma
... Abstract: Expression of podoplanin in glial brain tumors is grade dependent. While serving as a marker for tumor progression and modulating invasion in various neoplasms, little is known about podoplanin function in ...
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Combination of baicalein and temozolomide eradicates malignant glioma through cell apoptosis
... Human Glioma Cell line came from Cellular and Molecular Lab of Pathogenic Biology Key Discipcine (Qindao, China)that were cultured in High Dulbecco’s modified Eagle’s medium (DMEM)supplemented with 10% fetal ...
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Selective increase in subtelomeric DNA methylation: an epigenetic biomarker for malignant glioma
... gliomagenesis was noticed at all age groups compared to control patients, which also makes these CpG sites good biomarker candidates for early detection of dis- ease. We cross-validated the MSP results with the change in ...
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DWI for Monitoring the Acute Response of Malignant Gliomas to Photodynamic Therapy
... In summary, our findings suggest that a linear high signal on DWI accompanied by a decline in ADC val- ues after PDT are purely PDT-induced MR imaging changes. Although PDT- induced MR imaging changes on DWI and in ADC ...
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Original Article Serum microRNA-451a expression and its diagnostic value in glioma
... in malignant gli- omas which make them act as biomarkers in the diagnosis or prognosis or both of them ...grade malignant glioma compared with the control group which indicated that miR- 21 might be ...
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