Malignant transformation
p16 promoter methylation is a potential predictor of malignant transformation in oral epithelial dysplasia
... Management of the patient with oral epithelial dysplasia depends on the ability to predict malignant transformation. Histological grading of this condition fails in this regard and is also subject to inter ...
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Hepatocellular adenoma with malignant transformation in male patients with non-cirrhotic livers
... of malignant transformation of HCAs cannot be reliably quantified ...of malignant transformation is associated with the subtype of mutated β-catenin and the size of the HCA ...that ...
8
Elucidating drivers of oral epithelial dysplasia formation and malignant transformation to cancer using RNAseq
... present at that disease stage. Analysis of an independent cohort of unmatched N, D and T samples (from microarray study GSE30784) also supported this finding, despite the study design negating our ability to investigate ...
16
Metachronic malignant transformation of small bowel and rectal endometriosis in the same patient
... of malignant transformation of extragonadal endometriosis and the lack of an adequate classification, conclusions about the utility of chemother- apy are only drawn from studies that also include malig- ...
6
Identification of 3 subpopulations of tumor-infiltrating immune cells for malignant transformation of low-grade glioma
... MT: malignant transformation; LGG: low-grade glioma; HGG: high-grade glioma; CIBERSORT: Cell type Identifica- tion By Estimating Relative Subsets Of RNA Transcripts; AUC : area under curve; TFH: T ...
13
A giant pelvic epidermoid cyst with malignant transformation to squamous cell carcinoma
... was made on a core needle biopsy on surgical exploration after percutaneous core biopsy under ultrasound guidance demonstrating unknown origin malignant cell. The patient underwent four courses of chemotherapy ...
5
Malignant Transformation of Radicular Cyst/Residual Cyst: A Review of Literature
... neoplastic transformation is considered to be highest in keratocyst and dentigerous cyst ...concerning malignant transformation of radicular/residual ...
11
Human villous adenomas engrafted into scid mice survive for prolonged period without malignant transformation
... Human villous adenomas are thought to represent premalignancies that subsequently give rise to colorectal adenocarcinomas. Currently there is no in vivo model in which to study the dedifferentiation and malignant ...
6
Genomic dynamics associated with malignant transformation in IDH1 mutated gliomas
... that malignant transformation of low-grade gliomas (LGGs) occurs in 45% of oligodendrogliomas, 70% of oligoastrocytomas, and 74% of astrocytomas ...before malignant transformation in ...
14
Expression of ΔNp63 in Oral Submucous Fibrosis and Malignant Transformation of Oral Submucous Fibrosis
... Oral submucous fibrosis is a chronic progressive disorder affecting the oral mucosa. It is a potentially malignant disorder. It is of interest to develop markers which could detect early genetic changes in OSF ...
113
Expression of Telomerase Reverse Transcriptase during the Malignant Transformation of Cadmium Induced Cells
... chloride-induced malignant transformation of 16HBE cells was reported in our previous study (Lei, ...Cd-induced malignant transformation (passages 15 and 35), and tumorigenic cells from nude ...
5
Recurrent ovarian mixed germ cell tumor with unusual malignant transformation: a case report
... reported in only two out of eight immature teratoma pa- tients with greater than 15-year remission in both cases (186 and 202 months respectively). Rezk Y et al. reported a case similar as ours [18] with a grade 3 ...
6
Malignant Transformation in Leukoplakia and its Associated Factors in Southern Iran: A Hospital Based Experience
... of malignant transformation were seen in females, however, this difference was not statistically significant ...for malignant change, however unlike our study they did not document a significant ...
8
<p>KNDC1 Is a Predictive Marker of Malignant Transformation in Borderline Ovarian Tumors</p>
... a crucial role in cervical epithelial carcinogenesis. 38 Taking together, KNDC1 may exert its function through regulation of the MAPK signaling pathway. Previous research showed that knockdown of KNDC1 can not only ...
10
PIAS3-mediated feedback loops promote chronic colitis-associated malignant transformation
... Although PIAS3/STAT3 (NF-κB)/miR-18a autoregulatory loops were found in CAC, these circuits might affect other oncogenic signaling pathways. For example, STAT3 and NF-κB were found to promote the transcription of other ...
16
A case of recurrent giant cell tumor of bone with malignant transformation and benign pulmonary metastases
... In karyotypic analysis of giant cell tumors of bone, end-to-end fusions of various chromosomes, termed telomeric associations, are seen in most tumors in a subset of cells, and these have been localized by FISH studies ...
7
Secondary chondrosarcoma: Malignant transformation of pre-existing hereditary and non-hereditary cartilaginous lesions
... undergo malignant transformation to chondrosarcoma. Malignant transformation occurs in up to 25% of cases, especially if the lesions are located in the pelvis or ...
5
A case of biliary adenofibroma of the liver with malignant transformation: a morphomolecular case report and review of the literature
... Tsui et al. [2] were the first to describe this cystic liver lesion as a benign, complex, tubulocystic tumor with a bland spindle-cell stromal component. To date, there are only 21 case reports in the literature, 7 of ...
6
Case Report Malignant transformation of benign thyroid nodule is caused by prolonged H
... forms, 7-17% cases have been shown to be cancerous [11-14]. Presence of nodules in young males is indicative of higher risk of thy- roid cancer, while toxic and non-toxic nodular goiters are more prone to undergo ...
17
Determinants of Malignant Transformation in Fibrocystic Disease of Breast
... The case presented highlights the fact that fibrocystic disease of breast in middle aged women should be taken seriously. Multiplicity of the cysts, the histology of the cysts removed previously and recurrence of the ...
5