Mammary Carcinoma
Aberrant E cadherin staining patterns in invasive mammary carcinoma
... lolobular carcinoma based on the hybrid morphology of gland (tubules) and linear (lobular) growth ...ulolobular carcinoma is a distinct subtype of mammary carcinoma, which were originally ...
10
Co-cultivation of murine BMDCs with 67NR mouse mammary carcinoma cells give rise to highly drug resistant cells
... Results: Hygromycin resistant murine 67NR-Hyg mammary carcinoma cells were co-cultivated with puromycin resistant murine BMDCs from Tg(GFPU)5Nagy/J mice. Isolation of hygromycin/puromycin resistant ...
13
Ultrasound ablation enhances drug accumulation and survival in mammary carcinoma models
... and to determine where delivery is enhanced. We first applied ultrasound to a single point at the center of the tumor to assess the surrounding nanoparticle accumulation, with temperatures greater than 65°C. This ...
14
Utility of Isatin Semicarbazones in Mammary Carcinoma Cells - A Proof of Concept Study
... Objective: The present study was aimed to determine cytotoxic and apoptotic activity of isatin semicarbazones against mammary carcinoma. Methodology: The preparation of these target compounds involved sub- ...
6
A candidate metastasis associated DNA marker for ductal mammary carcinoma
... in mammary carcinomas in par- ticular, is still ...primary mammary carcinoma cells must acquire genetic changes in addition to those changes that led to ...ductal mammary carcinoma ...
7
Metastasis of Mammary Carcinoma in Bitches: Evaluation of the Sentinel Lymph Node Technique
... Nodal metastasis is one of the key prognostic factors in both women and female dogs suffering from mammary neoplasias, being directly related to survival. In addition, they represent the first phase of the tumor’s ...
8
Methylation Abnormalities in Mammary Carcinoma: The Methylation Suicide Hypothesis
... We did confirm that genome-wide demethylation is a common event in mammary carcinoma [1]. Demethyla- tion is quantitatively the most prominent methylation abnormality found in cancer genomes, but the ...
15
The MMTV PyVT Transgenic Mouse as a Multistage Model for Mammary Carcinoma and the Efficacy of Antineoplastic Treatment
... This study looks at the transgenic PyVT mouse as a model for breast cancer research and drug development. Tumor growth was monitored from a precancerous stage to a metastatic stage. The tumor phenotype was deter- mined ...
11
CEACAM1 controls the EMT switch in murine mammary carcinoma in vitro and in vivo
... of mammary adenocarcinoma in humans [10–15]. In WAP-T mice, mammary glands develop ...the mammary gland and drives expression of the simian virus 40 (SV40) large tumor antigen (LT), which compromises ...
17
NEW PROSPECTS FOR THE THERAPY OF THE PATIENTS WITH DISSEMINATED MAMMARY CARCINOMA
... At the same time, median duration of the objective response for the known cytostatics both in mono-regime and combination as chemotherapy of the first line constitutes 6 to 8 months and [r] ...
10
Radiosensitization of mammary carcinoma cells by telomere homolog oligonucleotide pretreatment
... murine mammary tumor induced by PyMT shares many features with poor-prognosis human breast cancer such as a high frequency of distant metastases, persistent expression of biomarkers, ErbB2/Neu and cyclin D1, and ...
11
A long pentraxin-3-derived pentapeptide for the therapy of FGF8b-driven steroid hormone-regulated cancers
... Fibroblast growth factor-8b (FGF8b) affects the epithelial/stromal compartments of steroid hormone-regulated tumors by exerting an autocrine activity on cancer cells and a paracrine pro-angiogenic function, thus ...
13
Bisphosphonates inhibit the adhesion of breast cancer cells to bone matrices in vitro
... Figure 1. Dose–response relationships of various bisphosphonates on adhesion of mammary carcinoma cells (MDA-MB-231) to bovine cortical bone slices. After 18 h of pretreatment of the bone slices with ...
9
Comparative aspects of canine and human inflammatory breast cancer
... Inflammatory breast cancer in humans (IBC) is the most aggressive form of mammary gland cancer and shares clinical, pathological and molecular patterns of disease with canine inflammatory mammary ...
33
CHARACTERIZATION OF MAMMARY GLAND TISSUE USING JOINT ESTIMATORS OF MINKOWSKI FUNCTIONALS
... From Fig. 4 one can see that it is not possible to base the decision whether an image shows mammary carcinoma or not only on the mean curvature density. Also a statistical test of the mean surface area per ...
10
In Vitro Characterization of Docetaxel as a Radiosensitizer in Canine and Feline Cancer Cell Lines
... (mammary carcinoma— CMT12 and CMT25, ...cell carcinoma—PTCC), and one feline cancer cell line (oral squamous cell carcinoma—SCCF1) to provide a basis for combination therapy in clinical ...
8
Synthesis of highly substituted 1,2 diazetidin 3 ones, small ring scaffolds for drug discovery
... 1,2-Diazetidin-3-ones are readily accessible, small ring scaffolds that upon functionalization have the potential to produce diverse 3-dimensional structures for drug discovery. Thus treatment of diazo hydrazides, ...
14
Notch signaling as a therapeutic target for breast cancer treatment?
... Parr and colleagues [10] reported that high Notch2 mRNA expression levels were associated with good clinical outcomes, thus suggesting a tumor suppressor role for Notch2 in breast cancer. Th is hypothesis was supported ...
8
Abrogation of TGF β signaling enhances chemokine production and correlates with prognosis in human breast cancer
... Loss of TGF-β signaling in mammary carcinoma cells resulted in a signa- ture that correlated with increased risk of relapse during human breast cancer progression. (A) The TGF- β signature correlation with ...
13
Molecular analysis of metastasis in a polyomavirus middle T mouse model: the role of osteopontin
... mouse mammary carcinoma transplant lines (termed Met and Db) that display significant differences in metastatic potential ...study mammary carcinoma because there is rapid mammary tumor ...
13