Mammary epithelial cells
New insights into lineage restriction of mammary gland epithelium using parity identified mammary epithelial cells
... hormone-sensing cells of developing alveoli are not generated by parity-identified mammary epithelial cells At low magnification, clusters of alveoli appeared to be clonally derived from ...
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Mouse Mammary Tumor Virus Suppresses Apoptosis of Mammary Epithelial Cells through ITAM-Mediated Signaling
... hematopoietic cells use a common signaling pathway that relies on a highly conserved immunoreceptor ty- rosine-based activation motif (ITAM), which signals through Src family tyrosine ...mouse mammary tumor ...
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An oestrogen dependent model of breast cancer created by transformation of normal human mammary epithelial cells
... for mammary epi- thelial progenitor cells, but it is possible that expression of BMI1 promotes the survival of more differentiated cells or, conversely, forces progenitors to adopt a more ...
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Mouse mammary tumor gene int-3: a member of the notch gene family transforms mammary epithelial cells.
... To determine the biological consequences of activated int-3 expression on mammary epithelial cells, we transfected the HC11 mouse mammary epithelial cell line 4 with a genomic DNA fragme[r] ...
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REPLICATION OF CHROMATIN IN MOUSE MAMMARY EPITHELIAL CELLS GROWN IN VITRO
... The observation of two classes of labelled interphase nuclei, namely, cells with silver grains located in only euchromatic regions (Figures g,h) and cells with silver grains [r] ...
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Cytogenetic characterization and H-ras associated transformation of immortalized human mammary epithelial cells
... SKY [22] was used to identify or confirm the G-band kary- otype assignments. Briefly, SKY is a form of fluorescence in situ hybridization (FISH) which utilizes a mixture of "whole chromosome paint" DNA probes to ...
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Age- and Pregnancy-Associated DNA Methylation Changes in Mammary Epithelial Cells
... on mammary epithelial cell differentiation (Mi- chalak et ...the mammary gland, the physiologic relevance of their expres- sion and epigenetic patterns is still ...mary epithelial stem or ...
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A co culture genome wide RNAi screen with mammary epithelial cells reveals transmembrane signals required for growth and differentiation
... 3T3 cells were plated with four hundred 184- hTERT -GFP cells in 96-well plates prior to transfection with ...hTERT cells infected with an independently designed lentiviral shRNA construct were ...
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Serially transplantable mammary epithelial cells express the Thy 1 antigen
... med cells had unique global gene expression profiles in both C57BL6 and FVB mice ...high cells expressed the highest level of genes that have previously been linked to mammary gland stem cells ...
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Contribution of mammary epithelial cells to the immune response during early stages of a bacterial infection to Staphylococcus aureus
... proteins (APP): pentraxin 3 (PTX3) and α-1 anti- proteinase (SERPINA1) which were also found in bovine milk at the beginning of mastitis [39,42]. We demonstrate here from LCM experiments that MEC contribute significantly ...
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The receptor protein tyrosine phosphatase PTPRB negatively regulates FGF2 dependent branching morphogenesis
... the mammary gland, suggested that PTPRB may be a negative regulator of mammary ...mouse mammary epithelial cells were transduced in short-term culture (48 h) with either a pooled ...
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Epigenetic response in mice mastitis: Role of histone H3 acetylation and microRNA(s) in the regulation of host inflammatory gene expression during Staphylococcus aureus infection
... Bovine mammary epithelial cells (MEC) is a good model system to study host immune response during bacteria-induced mastitis, but recent reports have shown that it poorly mimics whole animal data ...
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PubMedCentral-PMC4972522.pdf
... 1995). However, no mechanism of infection has been identi fi ed. Two re- cent analyses of the RNAseq data in the TCGA dataset did not show ev- idence for actively transcribed virus (Khoury et al., 2013b; Tang et al., ...
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The receptor protein tyrosine phosphatase PTPRB negatively regulates FGF2-dependent branching morphogenesis.
... the mammary gland, suggested that PTPRB may be a negative regulator of mammary ...mouse mammary epithelial cells were transduced in short-term culture (48 h) with either a pooled ...
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Merging perspectives: genotype-directed molecular therapy for hereditary diffuse gastric cancer (HDGC) and E-cadherin–EGFR crosstalk
... HDGC cells which identified drug classes targeting PI3K (phosphoinositide 3-kinase), MEK (mitogen-activated protein kinase), FAK (focal adhesion kinase), PKC (protein kinase C), and TOPO2 (topoisomerase II) as ...
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Human mammary cancer progression model recapitulates methylation events associated with breast premalignancy
... breast cells or ...these cells, despite their normal histological ...of mammary epithelial cells in vitro, is biologically relevant in that it can also be detected in both breast cancer ...
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A novel approach for the generation of genetically modified mammary epithelial cell cultures yields new insights into TGFβ signaling in the mammary gland
... phenotypically epithelial under permissive or non- permissive conditions and have not transformed during the time we have maintained them in culture (up to 60 ...our mammary epithelial cells ...
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Linear and cooperative signaling: roles for Stat proteins in the regulation of cell survival and apoptosis in the mammary epithelium
... tumor cells, thus its inhibition will cause few undesirable side ...and mammary epithelial cells A prerequisite for such an approach is the detailed under- standing of the function of ...
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CD24 staining of mouse mammary gland cells defines luminal epithelial, myoepithelial/basal and non epithelial cells
... single mammary cell suspensions The fourth mammary fat pads were harvested from 20 virgin female 10 to 12 week old FVB mice following removal of the intra-mammary lymph ...of epithelial tissue ...
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Aptamer-labeled PLGA nanoparticles for targeting cancer cells
... cancer cells with controlled drug release for cancer ...human mammary epithelial cells (HMEC cells) and human glial cancer cells (GI-1 cells) by methylthiazolyldiphenyl- ...
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