Mammary tumorigenesis
Gut bacteria require neutrophils to promote mammary tumorigenesis
... develop mammary cancer ...and mammary cancer [28, ...and mammary intraepithelial neoplasia (MIN), which corresponds to the human ductal carcinoma in situ ...increases mammary tumor ...
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Biological properties of blueberries and their effects on breast cancer in DMBA induced mammary tumorigenesis rat model : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Nutritional Science at Massey University, Palmerston North, New Zealand
... of mammary gland proliferation which contributes to disease ...E2-induced mammary tumorigenesis which might result in lower carcinogenic metabolites of estrogen (Aiyer & Gupta, ...
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The DNA resection protein CtIP promotes mammary tumorigenesis
... promote tumorigenesis, we have examined its oncogenic potential in mouse models of human breast ...Moreover, mammary-specific biallelic CtIP ablation did not elicit breast tumors in a manner reminiscent of ...
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BALB/Mtv-Null Mice Responding to Strong Mouse Mammary Tumor Virus Superantigens Restrict Mammary Tumorigenesis
... of mammary carcinomas within ⬃ 8 months of infection (Table ...FM-MMTV-induced mammary tu- ...2C). Mammary glands (lane 1), spleens (lanes 7, 18, and 19), and salivary glands (lanes 22 and 23) from ...
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Kinase-independent role of cyclin D1 in chromosomal instability and mammary tumorigenesis
... mammary tumorigenesis, transgenicmousemodelsweredeployedusingeitherthe tetracycline-induciblecyclinD1transgenicmice(rtTA/ CCND1),thePonasteroneinduciblemammaryepithelial cell targeted ...
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p16 INK4a suppresses BRCA1-deficient mammary tumorigenesis
... the mammary gland and were highly composed of lymphoma cells, as evidenced by their lymphocyte-like morphology, positivity for CD45 and CD31 by FACS analysis and negativity for Cdh1, an epithelial cell marker, by ...
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Original Article Effects of Scribble on mammary tumorigenesis and metastasis in breast cancer
... on mammary tumori- genesis and ...of mammary glands were collected from our ...in mammary tumorigenesis and metastasis, indicating that Scrib can be a a potentially invaluable therapeutic ...
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Hormone induced protection of mammary tumorigenesis in genetically engineered mouse models
... Finally, it is apparent that the preventive activity can be induced by a modest dose of estrogen alone (100 μg) or a combined dose of estrogen and progesterone. Previously we had shown that short-term sustained exposure ...
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Hunk is required for HER2/neu induced mammary tumorigenesis
... Hunk is required for HER2/neu-induced mammary tumorigenesis. Our observations that HER2/neu activation rapidly upregulates Hunk in vivo and in vitro, and that Hunk is preferentially expressed in ...
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The glucose transporter GLUT1 is required for ErbB2 induced mammary tumorigenesis
... the mammary lymph node from the NIC-GLUT1 F/F mouse ...Neu-induced mammary tumorigenesis, and that loss of only a single copy of Slc2a1 is sufficient to prevent the majority of Neu-induced ...
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Roles of BCCIP deficiency in mammary tumorigenesis
... to mammary tumorigenesis, especially for a subset of breast cancers with 53BP1 abnormality, and to reveal the mechanistic implications of BCCIP in breast cancer ...the mammary glands, resembling the ...
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Mammary tumorigenesis in feral Mus cervicolor popaeus.
... Results of our study of mammary tumorigenesis in feral mice demonstrate that viral-induced rearrangement and activation of the int loci are not limited to the genetic background of inbre[r] ...
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Puberty specific promotion of mammary tumorigenesis by a high animal fat diet
... and mammary tis- sues were either snap-frozen for protein and RNA isola- tion or formalin-fixed and either processed as whole mounts [7] or paraffin-embedded for hematoxylin and eosin (H&E) staining and ...
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Mammary tumorigenesis in feral mice: identification of a new int locus in mouse mammary tumor virus (Czech II)-induced mammary tumors.
... Analysis of mammary tumors from the C3H and BR6 mouse strains led to the identification of two cellular genetic loci designated int-i and int-2 which are frequently occupied by an MMTV g[r] ...
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The effect of dietary zinc - and polyphenols intake on DMBA-induced mammary tumorigenesis in rats
... the mammary gland, probably because they receive a higher amount of ...induced mammary cancer in rats and estrogen-induced kidney cancer in hamsters ...
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Putting the brakes on mammary tumorigenesis: Loss of STAT1 predisposes to intraepithelial neoplasias
... cancers had partially lost or down-regulated STAT1 protein expression. Similar observations were reported in human patients, where low levels of STAT1 activation have been linked to a poor prognosis [5, 27]. The ...
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Hormonal regulation of murine mammary tumor virus RNA expression during mammary tumorigenesis in BALB/c mice.
... The effects of exposure to glucocorticoids and prolactin on MuMTV RNA expression in Viral RNA %c Hormone treatmentb MuMTV Type C 0.0018 0.0940 Control 0.0014 0.3894 Dexamethasone 0.0014 [r] ...
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Defining a role for the homeoprotein Six1 in EMT and mammary tumorigenesis
... in mammary epithelial cells show increases in stem/progenitor cell populations and subsequent tumor development, while in a separate study Micalizzi and colleagues show that overexpression of Six1 facilitates ...
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Murine Mammary Tumor Virus Expression During Mammary Tumorigenesis in BALB/c Mice
... In these studies, hormoneinduced BALB/c HAN lines, which were established from primary HAN induced in BALB/c mice by hormonal stimulation alone or in combination with DMBA, and mammary t[r] ...
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RARα1 control of mammary gland ductal morphogenesis and wnt1 tumorigenesis
... on mammary tumorigenesis. To test this, mammary glands of 40-MMTV-wnt1 and 42- MMTV-wnt1-RAR a 1/KO young female mice were pal- pated weekly for 40 weeks, and the appearance of palp- able tumors was ...
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