mantle cell lymphoma
Original Article Discordant lymphoma consisting of mantle cell lymphoma and angioimmunoblastic T cell lymphoma: homology or heterogeneity?
... Composite lymphoma (CL) is defined as two or more kinds of lymphoma detected in the same sample while discordant lymphoma (DL) is rec- ognized as different kinds of lymphoma occur- ing in ...
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An unusual initial presentation of mantle cell lymphoma arising from the lymphoid stroma of warthin tumor
... A thorough clinical staging is warranted in patients with mantle cell lymphoma, since most patients present with stage III or IV disease [18]. The patient was referred to his local medical ...
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Mantle cell lymphoma and its management: where are we now?
... Mantle cell lymphoma is a relatively new recognized hematological malignant disease, comprising of ...disease. Mantle cell international prognostic index (MIPI), ki-67 proliferation ...
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Coexisting Mantle Cell Lymphoma and Prostate Adenocarcinoma
... The blood work showed white blood cell count of 4.2˜× 10 9 /L (normal: 3.5–10.5 10 9 /L), consisting of 3.0 × 10 9 /L (normal: 2.0–7.5 × 10 9 /L) neutrophils, 0.6 × 10 9 /L (normal: 0.8–3.5 × 10 9 /L) lymphocytes, ...
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Novel targeted therapies for mantle cell lymphoma
... Mantle cell lymphoma (MCL) is an aggressive B-cell malignancy characterized by short median survival despite intensive ...in cell cycle dysregulation and give rise to profound genetic ...
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Targeting Wnt pathway in mantle cell lymphoma-initiating cells
... Wnt pathway genes are overexpressed in MCL-ICs Analysis from previous studies using unfractionated MCL cells have implicated the Wnt pathway in the pathogenesis of mantle cell lymphoma [12–14]. ...
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Emerging role of SOX11 in mantle cell lymphoma
... for mantle cell ...in mantle cell lymphoma and discuss the potential impact in relation to tumorigenesis, diagnostics, prognostics, and ...
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Original Article Double-hit mantle cell lymphoma with MYC gene rearrangement or amplification: a report of four cases and review of the literature
... blastoid mantle cell lymphoma with high circulating lymphoma cells and sple- nomegaly to determine MYC gene amplifica- tion, if conventional cytogenetics does not detect 8q24 translocation or ...
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Management of mantle cell lymphoma in the elderly patient
... Abstract: Mantle cell lymphoma is a relatively rare B-cell lymphoma with a specific genetic lesion and a typical immunophenotypic ...stem cell transplantation for a selected ...
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Synchronous Adenocarcinoma and Mantle Cell Lymphoma of the Stomach
... of mantle cell lymphoma (MCL) and gastric cancer in the same patient has not yet been reported in the English ...non-Hodgkin's lymphoma, and the current treatment approach is still ...
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Mantle cell lymphoma presenting as a pelvi ureteric junction obstruction: a case report
... Case presentation: A 78-year-old Caucasian woman was referred to our department with right flank pain, pyrexia and features of a urinary tract infection. A nephrostogram revealed a grossly distended right pelvicalyceal ...
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Gene mutations and actionable genetic lesions in mantle cell lymphoma
... We reviewed literature published in the last 10 years that describe recurrent gene mutations in mantle cell lymphoma and their role in the treatment bottleneck of drug resistance. We identified from ...
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Temsirolimus in the treatment of relapsed and/or refractory mantle cell lymphoma
... with mantle cell lymphoma (MCL) have a poor prognosis; consequently, new therapeutic approaches, such as rapamycin and its derivates, mammalian target of rapamycin (mTOR) inhibitors, are ...MCL ...
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Bortezomib in mantle cell lymphoma: comparative therapeutic outcomes
... Abstract: Mantle cell lymphoma (MCL) is an incurable, typically aggressive subtype of non-Hodgkin lymphoma, accounting for 4%–7% of newly diagnosed non-Hodgkin lymphoma ...
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Temsirolimus in the treatment of relapsed or refractory mantle cell lymphoma
... Abstract: Mantle cell lymphoma (MCL) is a rare and aggressive subtype of lymphoma associated with a poor ...integrating cell signals from growth factors, hormones, and nutrients and ...
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The role of B cell antigen receptors in mantle cell lymphoma
... the lymphoma entities has greatly ...the Mantle Cell Lymphoma International Prognostic Index [114, 115] or certain molecular fea- tures help to guide intensity of front line treatment, there ...
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<p>CD5-negative chronic lymphocytic leukemia/small lymphocytic lymphoma in a patient with gastrointestinal mantle cell lymphoma: an unusual case report</p>
... lymphocytic lymphoma (CLL/SLL) is common leukemia in adults and accounts for approximately 30% and 7% of lymphoid and nodal lymphomas, ...B cell lymphoma, Hodgkin ’ s lymphoma, and multiple ...
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Current trials for frontline therapy of mantle cell lymphoma
... Mantle cell lymphoma is a rare disease with limited re- sources and its treatment targeting pathways are a compos- ition of the treatment of other hematological malignancies such as follicular ...
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NF-κB signaling and its relevance to the treatment of mantle cell lymphoma
... B cell-like diffuse large B cell lymphoma; BAFF/ TNFSF13B: B cell-activating factor; BAFFR: B cell-activating factor receptor; BCAP: B cell adaptor for phosphoinositide 3-kinase; ...
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Synchronous presentation of mantle cell lymphoma and plasma cell dyscrasia: A case report
... of mantle cell lymphoma and plasma cell dyscrasia involving the bone marrow is a very rare ...nodal mantle cell lymphoma involving nasopharynx without the plasma ...
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