MAPK Signaling Pathway
Cordyceps bassiana inhibits smooth muscle cell proliferation via the ERK1/2 MAPK signaling pathway
... In conclusion, CBEE exhibited anti-proliferative properties that affected VSMC through the ERK1/2 MAPK signaling pathway. Our data may elucidate the inhibitory mechanism of this natural product, ...
8
Adipose tissue-derived stem cells suppress hypertrophic scar fibrosis via the p38/MAPK signaling pathway
... in the anti-fibrotic properties of ADSC-CM. The in vitro experiment showed that ADSC-CM decreased collagen deposition and α-SMA expression in HSFs. Simultan- eously, the ex vivo study revealed that ADSC-CM treat- ment ...
16
Underexpressed CNDP2 Participates in Gastric Cancer Growth Inhibition through Activating the MAPK Signaling Pathway
... the MAPK signaling ...the MAPK pathway and the several key components and phospho- rylation events that play a role in regu- lating the cell cycle, apoptosis and even tumorigenesis ...the ...
12
<p>Moxibustion Eases Chronic Inflammatory Visceral Pain In Rats Via MAPK Signaling Pathway In The Spinal Cord</p>
... spinal MAPK signal- ing pathway using the 91-proteins microarray technique, to screen the pathways of MAPK that were possibly involved in moxibustion ...in MAPK (MAPK/ERK, ...
14
A Positive Feedback Loop of SLP2 Activates MAPK Signaling Pathway to Promote Gastric Cancer Progression
... progression through interacting with p53 and retinoblastoma tumor suppressor protein (RB) in the nucleus [29, 30]. Further evidences showed the anti-tumorigenic effect of PHB in prostate cancer [31] and liver cancer ...
14
NMDA receptor activation stimulates transcription-independent rapid wnt5a protein synthesis via the MAPK signaling pathway
... Wnt proteins are emerging key regulators of the plasticity and functions of adult brains. However, the mechanisms by which the expression of Wnt proteins is regulated in neurons are unclear. Using cortical primary ...
9
<p>FGF5 promotes osteosarcoma cells proliferation via activating MAPK signaling pathway</p>
... of MAPK signaling pathways. MAPK is an insulin-mitogen activated protein kinase, which is related with cell survival, growth, and migration by regulating the signals from cell surface to nucleus ...
10
Original Article CELF1 promotes colorectal cancer proliferation and chemoresistance via activating the MAPK signaling pathway
... Abstract: Colorectal cancer is the third most commonly diagnosed type of cancer worldwide with a high incidence and mortality rate. The long-term post-operational survival of colorectal cancer is limited by metastasis ...
8
Original Article Epinephrine increases malignancy of breast cancer through p38 MAPK signaling pathway in depressive disorders
... PI3K/AKT pathway in breast cancer cells, but can signifi- cantly regulate the p38 ...p38 MAPK signaling pathways depend on the type of ...p38 MAPK pathway significantly decreases liver ...
15
Original Article Propranolol induces apoptosis in endothelial cells by inhibiting Akt and ERK phosphorylation and MAPK signaling pathway
... (MAPK) signaling pathway were detected by Western-Blot and cAMP levels were measured by cAMP enzyme-linked immuno- sorbent assay (ELISA) ...and MAPK signaling ...
7
Original Article Emodin inhibits formation of hypertrophic scars through regulating the p38/MAPK signaling pathway
... cellular signaling pathways, includ- ing the p38/Mitogen-activated protein kinase (MAPK) signaling pathway, which functions through the mitochondrial death pathway [7] and cell ...
8
<p>Hypermethylation of the <em>IRAK3</em>-Activated MAPK Signaling Pathway to Promote the Development of Glioma</p>
... (MAPK) signaling pathway was ...the MAPK signaling pathway inhibitor PD325901 alone or the overexpression or demethylation of the IRAK3 had a similar effect as the overexpression ...
17
TRIB3 Promotes the Proliferation and Invasion of Renal Cell Carcinoma Cells via Activating MAPK Signaling Pathway
... Tribbles pseudokinase 3 (TRIB3) is a member of the mammalian pseudokinase tribbles family and is involved in multiple biological processes. However, the role of TRIB3 in renal cell carcinoma (RCC) remains unclear. In ...
11
miRNA-106a directly targeting RARB associates with the expression of Na+/I− symporter in thyroid cancer by regulating MAPK signaling pathway
... stem cell self-renewal, are highly induced during the early stages of cell reprogramming [24]. miR-106a is known to function in tumor-initiating cells and regulate tumor differentiation through the retinoblastoma (Rb) ...
12
miR-433 inhibits breast cancer cell growth via the MAPK signaling pathway by targeting Rap1a
... the MAPK pathway, and this function of miR-433 could act directly or indirectly through this ...ras/ERK signaling and the effect of Rap1 on cell proliferation has been closely ...the MAPK ...
11
Adenovirus infection stimulates the Raf/MAPK signaling pathway and induces interleukin-8 expression.
... Raf/ MAPK signaling pathway raises the possibility that activation of this pathway is necessary for efficient adenovirus ...Raf/MAPK signaling path- ...Raf/MAPK ...
7
<p>Sevoflurane Inhibits Proliferation and Invasion of Human Ovarian Cancer Cells by Regulating JNK and p38 MAPK Signaling Pathway</p>
... of MAPK signaling pathway-related factors, including p-p38, p38, p-JNK, JNK, p-ERK and ERK, were detected via Western ...of MAPK signaling ...
10
Original Article TRB3 regulates pulmonary interstitial fibrosis through the MAPK signaling pathway
... [9], MAPK [10], PI3K and other signaling ...of MAPK [9]. TRB3 can interact with MAPK kinase and regulate the relative activation of three types of MAPK ...of MAPK ...
11
Curcumin synergizes with resveratrol to stimulate the MAPK signaling pathway in human articular chondrocytes in vitro
... OA in humans as well as in animals [3, 21]. Resveratrol and curcumin are anti-inflammatory phytochemicals that have previously been shown to block some of the catabolic effects of TNF-a and IL-1b via inhibition of NF-kB ...
9
<p>TMEFF2 inhibits pancreatic cancer cells proliferation, migration, and invasion by suppressing phosphorylation of the MAPK signaling pathway</p>
... Methods: A total of 72 pancreatic cancer patients were enrolled. AsPC1 and Panc1 cells were transfected. SB203580 was used to treat AsPC1 cells. CCK8 assay, colony formation analysis, Transwell experiment and Tunel test ...
12