matrix metalloproteinase
Matrix metalloproteinase 9 modulates collagen matrices and wound repair
... Acute and chronic injuries are characterized by leukocyte infiltration into tissues. Although matrix metalloproteinase 9 (Mmp9) has been implicated in both conditions, its role in wound repair remains ...
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Original Article Correlation between matrix metalloproteinase-9 and endometriosis
... Abstract: Endometrial implantation is the major cause of endometriosis (EMS). Matrix metalloproteinase (MMPs) can degrade multiple extracellular matrix and has been postulated to be related with EMC ...
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The Distribution of Matrix Metalloproteinase-2, Tissue Inhibitor of Metalloproteinase-2 and Tissue Inhibitor of Metalloproteinase-4 in Psoriatic Skin
... The matrix metalloproteinase (MMP) family consists of a number of Zinc-dependent proteolytic ...1- matrix metalloproteinase (MT1-MMP) degrade extracellular matrix in arthritis, ...
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Update of human and mouse matrix metalloproteinase families
... the Matrix Metalloproteinase Conference (Destin, Florida 1989), MMPs were assigned sequential names and defined using biochemical characteristics, includ- ing: appearance in a latent form; inhibition by ...
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Serum Matrix Metalloproteinase 3 and Tissue Inhibitor Metalloproteinase 1 in Vascular Dementia: A Comparative Study
... of matrix metalloproteinase 3 (MMP3) and tissue inhibitor metallo- proteinase 1 (TIMP1) in vascular dementia patients and healthy control ...of matrix metalloproteinase 3 (MMP3) and tissue ...
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Expression of CD147 and matrix metalloproteinase 11 in colorectal cancer and their relationship to clinicopathological features
... lular matrix metalloproteinase inducer (EMMPRIN), is a member of the immunoglobulin superfamily of adhesion ...secrete matrix metalloproteinases ...
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Matrix metalloproteinase-2, tissue inhibitor of matrix metalloproteinase-2, and transforming growth factor beta 1 in the aqueous humor and serum of patients with pseudoexfoliation syndrome
... of matrix metalloproteinase-2 (MMP-2), its tissue inhibitor (TIMP-2) and transforming growth factor beta 1 (TGF-β1) in the aqueous humor and serum samples of patients with pseudoexfoliation (PEX) ...
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Original Article Immunohistochemical expression of matrix metalloproteinase-9 and inhibitor of matrix metalloproteinase-1 in prostate adenocarcinoma
... the matrix metalloproteinase-9 and the inhibitor of matrix metalloproteinase-1 was carried out at the benign prostatic hyperplasia (BPH) and the adenocarcinoma (AC) of different Gleason’s ...
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Increased matrix metalloproteinase-9 to tissue inhibitor of metalloproteinase-1 ratio in smokers with airway hyperresponsiveness and accelerated lung function decline
... Notes: aMs from ahr−ns (n=10), ahr−s (n=13) or ahr+s (n=8) were incubated for 24 hr. The level of MMP-9 (A) and TIMP-1 (B) in the culture supernatants was determined by enzyme-linked immunosorbent assays. The molar ratio ...
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Original Article Expression of matrix metalloproteinase-8 and matrix metalloproteinase-13 in mast cells of human periapical lesions
... of matrix metalloproteinase-8 (MMP-8) and MMP-13 in mast cells (MCs) of human periapical lesions and to discuss the pathogenic role of MCs in periapical ...
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What does matrix metalloproteinase-1 expression in patients with breast cancer really tell us?
... of matrix metalloproteinases in breast cancer tissue and cells offers promise in helping us understand the breast cancer microenvironment, and also in the future it is hoped this will improve its detection, ...
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Coordinated elevation of membrane type 1-matrix metalloproteinase and matrix metalloproteinase-2 expression in rat uterus during postpartum involution
... extracellular matrix, particularly collagen. Membrane type-I matrix metalloproteinase (MT1-MMP) is one of the major proteinases that degrades collagen and is the most abundant MMP form in the ...
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Characterization of a glomerular epithelial cell metalloproteinase as matrix metalloproteinase 9 with enhanced expression in a model of membranous nephropathy
... novel metalloproteinase within the crude membrane extracts of isolated whole glomer- uli, which demonstrated a molecular mass of 116–120 kD, and which was not inhibited by TIMP or activated by organomer- curial ...
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Original Article Serum levels of matrix metalloproteinase-2 and matrix metalloproteinase-9 have clinical significance for the evaluation of the prognosis of patients with ruptured intracranial aneurysms after interventional therapy
... of matrix metalloproteinase-2 (MMP-2) and matrix metalloproteinase-9 (MMP-9) before and after interventional therapy of ruptured intracranial aneurysm (IA), as well as their correlation with ...
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Matrix metalloproteinase expression and production by alveolar macrophages in emphysema
... of matrix-degrading proteinases in the emphysematous ...the matrix metallopro- teinases (MMPs) gelatinases A and B, macrophage metalloelastase (MME), and interstitial collage- ...of matrix-degrading ...
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The triterpenoid CDDO inhibits expression of matrix metalloproteinase 1, matrix metalloproteinase 13 and Bcl 3 in primary human chondrocytes
... A synthetic triterpenoid, 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid (CDDO), has been reported to have anti-inflammatory properties and to decrease the interleukin-1 (IL-1)-induced expression of matrix ...
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Is radiographic progression in radiographic axial spondyloarthritis related to matrix metalloproteinase degradation of extracellular matrix?
... Methods Patients from the Outcome in ankylosing Spondylitis international Study (OaSiS) were included if they had serum, clinical and spinal radiographic assessments available at baseline and 2 years later. two readers ...
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Elevated matrix metalloproteinase 9 in patients with systemic sclerosis
... The matrix metalloproteinases (MMPs) are a family of extra- cellular endopeptidases that selectively degrade the com- ponents of various extracellular ...of metalloproteinase-1 (TIMP-1), an inhibitor of ...
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Matrix metalloproteinase 14 is required for fibrous tissue expansion
... (d’Ortho et al., 1997; Ohuchi et al., 1997; Tam et al., 2004; Butler and Overall, 2007); therefore, the accumulation of FN in Mmp14-deficient tendon might be a direct result of the absence of MMP14. We observed a ...
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Matrix metalloproteinase 28, a novel matrix metalloproteinase, is constitutively expressed in human intervertebral disc tissue and is present in matrix of more degenerated discs
... Extracellular matrix localization of MMP28 in the disc The regulation of MMP activity is now recognized as an impor- tant factor in ECM regulation and degradation in the normal and degenerating intervertebral ...
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