Maximal electroshock seizure test
ANTI CONVULSANT POTENTIAL OF LEAVES OF PSIDIUM GUAJAVA LINN IN MES AND PTZ INDUCED CONVULSION IN EXPERIMENTAL ANIMALS
... The maximal electroshock seizure test induced by bilateral corneal or transauricular electrical stimulation, is thought to be predictive of anticonvulsant drugs effective against generalized ...
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Synthesis and anticonvulsantactivity of somechalconesincorporated hydrazide derivatives
... Maximal Electroshock Seizure Model (MES): Maximal electroshock seizure model was used in the present study to evaluate the anticonvulsant activity of the compounds on male wistar ...
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“Lamotrigine and Memory Impairment Associated with Generalized Seizures: A Study on Maximal Electroshock Seizure Model of Mice” by Asher John Mohan, Krishna Kamsagara Linganna, India.
... by maximal electroshock on every 7 th day and memory impairment activity by Morris water maze (MWM) task on every 8 th day for a 64 days treatment schedule was ...MWM test and decreased AChE and ...
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Comparison of the anticonvulsant potency of various diuretic drugs in the maximal electroshock-induced seizure threshold test in mice
... Amiloride administered systemically (i.p.) at doses of 5, 10, 50, 75, and 100 mg/kg elevated the threshold for MEST- induced seizures over the controls by 11.2%, 12.7%, 24.2%, 37.2%, and 51.2%, respectively (Table 1). ...
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EVALUATION OF ANTI-SEIZURE ACTIVITY OF THE THOTTEA SILIQUOSA EXTRACT ON MAXIMAL ELECTROSHOCK AND PENTYLENETETRAZOLE INDUCED SEIZURES IN ALBINO WISTAR RATS
... A shrub found in evergreen forests of Western Ghats from Konkan to Kerala. An erect medicinal plant with smooth yellowish grey bark, Alternate, aromatic leaves, purple or greenish flowers in clusters. The roots are used ...
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Anticonvulsant Activity of Glaucium vitellinum Boiss and Buhse
... The anticonvulsant activities of Glauciumvitellinum extract and alkaloid sub-fraction were assessed in pentylenetetrazole (PTZ)-induced convulsion and maximal electroshock test (MEST) in mice, with ...
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Anthelmintic and Anticonvulsant Studies of Ethanolic Extract of Benincasa Hispida Seeds.
... The maximal electroshock test is the most widely used animal model in antiepileptic drug discovery, because seizure induction is simple and the predictive value for detecting clinically ...
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IN VITRO STUDY OF ANTICONVULSANT ACTIVITY ON THE FRUITS EXTRACTS OF COCCINIA INDICA (WIGHT &ARN ) INDUCED MAXIMAL ELECTROSHOCK SEIZURE (MES) MODEL IN RATS
... Materials & methods: For the assessment of anticonvulsant activity, the animals were divided into five groups of five animals each albino rats. Group I received Normal saline, Group II received Phenytoin, Group III ...
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Anti-Seizure Activity of Tabernaemontana Divaricata against Maximal Electroshock and Pentylene Tetrazole Induced Convulsions in Animals
... induced seizure models are the most commonly used preliminary screening tests to evaluate anti- convulsant potential of ...in seizure threshold (24). PTZ test represents a valid model for human ...
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ANTICONVULSANT ACTIVITY OF ETHANOLIC EXTRACT OF VITEX NEGUNDO FLOWERS IN EXPERIMENTAL ANIMALS
... Maximum Electroshock induced Seizure (MES) model in experimental ...giving maximal electric shock of 150 mA for ...In Maximal electric shock induced seizure (MES) Model, EEVNF in doses ...
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ANTICONVULSANT ACTIVITY OF SUBSTITUTED BENZALDEHYDE SALICYLOYL HYDRAZONES AGAINST PTZ AND MES INDUCED SEIZURES
... MES test at short and long time period (2 h and 24 h, ...enhanced seizure protection ‒ compound 3 showed high potency against generalized clonic-tonic and absence ...
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Anticonvulsant Activity of Aqueous Extract of Aquilaria Agallocha.
... Female Swiss albino mice (18-22 g) were individually identified and allowed to acclimate to the laboratory conditions for 7 days before the start of the study. Only one mouse received a dose at a particular time. First ...
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Journal of Applied Pharmaceutical Science
... Light - dark test measures was summarized in Table 2. Diazepam (1mg/kg) and EECM (200 and 400mg/kg) significantly increased time spent in light arena 166.17±3.45 and 174.67±2.66, in dark 133.83±3.48 and ...
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Beneficial Role of Selenium Supplementation Against Experimental Seizures in Rats
... This study was designed to evaluate the antiseizure effect of Sodium selenite in the animal models of maximal electroshock seizures (MES) and pentylenetetrazole (PTZ) induced seizures. Healthy, male albino ...
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ANTICONVULSANT ACTIVITY OF ETHANOLIC EXTRACT OF SOLANUM MELONGENA LINN ROOTS
... by maximal electroshock, Pentylenetetrazole and ...against maximal electroshock induced seizure and pentylenetetrazole induced ...induced seizure, the extract at a dose of 200 ...
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Anticonvulsant and CNS Depressant Activity of Methanolic Extracts of Whole Plant of Sida acuta and Sida rhombifolia in Mice
... on maximal electroshock (MES) induced seizures and Pentylenetetrazole (PTZ) induced seizures and CNS depressant activity at the same dose level using traction test, rota rod and locomoter activity in ...
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Multi Stage 20 m Shuttle Run Fitness Test, Maximal Oxygen Uptake and Velocity at Maximal Oxygen Uptake
... Billat VL, Slawinski J, Bocquet V, Demarle A, Lafitte L, Chassaing P, Koralsztein JP. Intermittent runs at the velocity associated with maximal oxygen uptake enables subjects to remain at maximal oxygen ...
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Stationary roller versus velodrome for maximal cycling test: A comparison
... In agreement with Padilla et al. (1996), we also suggest that physiological values measured in a laboratory should be expressed in relation to body surface area or body mass, to better predict the actual performance of ...
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Fourth Amendment Protection against Unreasonable Seizure of the Person: The New Common Law Arrest Test for Seizure
... Yet, even in those days the common law provided the citizen with protec29 tion against an attempt to make an unlawful arrest."' Justice Stevens condemned the majority's decision to remov[r] ...
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THE PHYSIOLOGICAL MEANING OF THE MAXIMAL OXYGEN INTAKE TEST
... Mean values for 0, content, 0, tension, per cent saturation, pH and hematocrit from one arterial and two venous sites at rest and during exercise at maximal oxygen intake level Site.. Br[r] ...
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