Mediated Endocytosis
Influenza Virus Can Enter and Infect Cells in the Absence of Clathrin-Mediated Endocytosis
... clathrin-mediated endocytosis, we demonstrate that while transferrin uptake and Semliki Forest virus infection were prevented, influenza virus could enter and infect cells expressing Eps15 ⌬ ...block ...
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Human Rhinovirus Type 2 Is Internalized by Clathrin-Mediated Endocytosis
... clathrin-mediated endocytosis should be interpreted ...virus endocytosis by direct examina- tion with a confocal microscope; this method is particularly appropriate in the case of HRV2 ...
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Entry of Feline Calicivirus Is Dependent on Clathrin-Mediated Endocytosis and Acidification in Endosomes
... when increasing amounts of FCV were added, the levels of host cell translation were reduced compared to uninfected cells and untreated cells, indicating that the toxin was able to gain entry during FCV infection. Effects ...
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Transcriptomic analyses reveal clathrin-mediated endocytosis involved in symbiotic seed germination of Gastrodia elata
... plant endocytosis is in communication with the environment, including nutrient uptake, toxin avoidance, and pathogen ...moment, endocytosis is generally divided into clathrin-mediated ...
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Hepatitis C Virus Entry Depends on Clathrin-Mediated Endocytosis
... HCVpp entry is clathrin dependent. The pH dependency of HCVpp entry implies that HCVpp fusion does not occur at the plasma membrane but from within an intracellular acidic com- partment, most probably an endosome. To ...
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Dissecting Bacterial Cell Wall Entry and Signaling in Eukaryotic Cells: an Actin Dependent Pathway Parallels Platelet Activating Factor Receptor Mediated Endocytosis
... clathrin- mediated endocytosis which is dynamin dependent) by A549 and HBMEC treated with dynasore was reduced by 20 and 40%, re- spectively (see ...
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JC Polyomavirus Entry by Clathrin-Mediated Endocytosis Is Driven by β-Arrestin
... IMPORTANCE Viruses usurp cellular factors to invade host cells. Activation and utili- zation of these proteins upon initiation of viral infection are therefore required for productive infection and resultant viral ...
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Involvement of Clathrin-Mediated Endocytosis in Human Immunodeficiency Virus Type 1 Entry
... of endocytosis for productive entry of HIV-1 was investigated by using trans dominant-negative pro- teins that interfere with specific endocytic ...clathrin-mediated endocytosis by a dominant-nega- ...
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Cell Entry of Borna Disease Virus Follows a Clathrin-Mediated Endocytosis Pathway That Requires Rab5 and Microtubules
... receptor-mediated endocytosis, previous studies documented the requirement of a pH-dependent fusion event between cellular and viral mem- branes for the release of BDV RNPs into the cell cytoplasm (19) and ...
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End3p-Mediated Endocytosis Is Required for Spore Wall Formation in Saccharomyces cerevisiae
... The endocytosis-deficient mutant, end3⌬, sporulated poorly and the spores produced lost resistance to ether vapor, suggesting that END3-mediated endocytosis is important for ...END3- mediated ...
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Equine Infectious Anemia Virus Entry Occurs through Clathrin-Mediated Endocytosis
... have been identified. In the case of influenza virus, the con- formation of the intact viral glycoprotein is altered under low-pH conditions (65). In contrast, the viral surface glyco- protein of such viruses as Ebola ...
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Weak molecular interactions in clathrin mediated endocytosis
... individual sites on the TD, respectively, giving a total of 3 binding sites. However, data published since then has suggested that such a situation is likely to be an oversimplification. For example, yeast epsin (Ent2p) ...
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Inhibitor analysis revealed that clathrin mediated endocytosis is involed in cellular entry of type III grass carp reovirus
... Compared to GCRV-JX01, GCRV104 replication was slower and its CPE was detectable five days post infection (Fig. 1). Figure 2 suggest that a productive GCRV104 entry is pH-dependent. We used dynasore to determine whether ...
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Non specificity of Pitstop 2 in clathrin mediated endocytosis
... clathrin-mediated endocytosis are highly desired for the dissection of membrane trafficking pathways in the lab and for potential use as anti-infectives in the ...clathrin-mediated endocytosis ...
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ENTH and ANTH domain proteins participate in AP2 independent clathrin mediated endocytosis
... Clathrin-mediated endocytosis (CME) is a major route of entry into eukaryotic cells. A core of evolutionarily ancient genes encodes many components of this system but much of our mechanistic understanding ...
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An unmet actin requirement explains the mitotic inhibition of clathrin mediated endocytosis
... temperature. The cells were permeabilised and then blocked for 20 min at room temperature. Cover slips were incubated with 0.3 µM DNaseI-Alexa488 and 1:2000 Phalloidin-TRITC, for 20 min Figure 7. Model to show ‘two ...
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Entry of sapelovirus into IPEC J2 cells is dependent on caveolae mediated endocytosis
... traditional CME. Among them, caveolae/raft dependent endocytosis is another well-characterized pathway. Cave- olae, flask-shaped invaginations characterized by enrich- ment of caveolin-1 protein, could be used by ...
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Receptor mediated endocytosis
... In general, macromolecular ligands bind to specific cell surface receptors which move to and cluster within specialized regions of the plasma membrane termed "coated pits" 4.. l-,gm diam[r] ...
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The Spike Protein VP4 Defines the Endocytic Pathway Used by Rotavirus To Enter MA104 Cells
... of endocytosis pathway employed for virus cell ...clathrin- mediated endocytosis to enter cells, regardless of the P genotype of the virus, the cell attachment receptor used, and whether virus ...
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Macropinocytotic Uptake and Infection of Human Epithelial Cells with Species B2 Adenovirus Type 35
... clathrin-mediated endocytosis, as concluded from insensitivity against dynamin inhibition by dynasore, domi- nant-negative constructs, or siRNA in HeLa-ATCC cells, Wi-38 human lung fibroblasts, A549 cells, ...
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