Melanin biosynthesis
Screening of extracts of Japanese woods for melanin biosynthesis inhibition
... nin biosynthesis inhibitory activity at the concentration of 100 ...have melanin biosynthesis inhibitory activity at a concentration higher than ...inhibited melanin biosynthesis less ...
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Expression of T4HR1, a 1,3,6,8 Tetrahydroxynaphthalene Reductase Gene Involved in Melanin Biosynthesis, Is Enhanced by Near Ultraviolet Irradiation in Bipolaris oryzae
... the melanin biosynthesis from ...a melanin biosynthesis ...other melanin biosynthesis genes (polyketide synthase gene [PKS1], scytalone dehydratase gene [SCD1], and 1,3,8-THN ...
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Laccases Involved in 1,8-Dihydroxynaphthalene Melanin Biosynthesis in Aspergillus fumigatus Are Regulated by Developmental Factors and Copper Homeostasis
... conidial melanin is associated with fungal virulence and resistance to various environmental ...(DHN) melanin is synthesized by enzymes encoded in a gene cluster in ...control melanin ...
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Effects of Myrica esculenta Bark Extracts on Melanin Biosynthesis
... In this study, we investigated the effect of crude extracts, de- rived from stem bark of Myrica esculenta on melanin produc- tion in mouse B16 melanoma cells. In response to α-mela- nocyte-stimulating hormone ...
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Melanin Biosynthesis in the Maize Pathogen Cochliobolus heterostrophus Depends on Two Mitogen-Activated Protein Kinases, Chk1 and Mps1, and the Transcription Factor Cmr1
... stress. Melanin is a dark pigment tissue considered to protect the fungus from environ- mental stresses such as UV irradiation (8, ...in melanin biosynthesis, including the polyketide syn- thase ...
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The Melanin Biosynthesis Stimulating Compounds Isolated from the Fruiting Bodies of Pleurotus citrinopileatus
... from melanin synthesis by melanocytes and is caused by exposure to UV ...of melanin synthesis that ca- talyzes three different reactions: the hydroxylation of ty- rosine to 3,4-dihydroxyphenylalanine ...
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Unraveling Melanin Biosynthesis and Signaling Networks in Cryptococcus neoformans
... ABSTRACT Melanin is an antioxidant polyphenol pigment required for the patho- genicity of many fungal pathogens, but comprehensive regulatory mechanisms re- main ...analyzed melanin-regulating sig- naling ...
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Inhibitory effect of Fucofuroeckol-A from Eisenia bicyclis on tyrosinase activity and melanin biosynthesis in murine melanoma B16F10 cells
... To further verify the inhibitory property of Fucofuroeckol-A on melanogenesis, we examined the inhibitory effect of Fucofuroeckol-A on IBMX-induced melanin synthesis in murine melanoma (B16F10) cells. We first ...
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Evaluation of biological activities of extracts from the fruiting body of Pleurotus citrinopileatus for skin cosmetics
... This study also found that some extracts showed higher cytotoxicity of more than 75% versus the control at a concentration of 100 μg/ml (e.g., the n-hexane-soluble fraction), which prohibited us from evaluating their ...
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A novel gene from a secondary metabolism gene cluster is required for microsclerotia formation and virulence in Verticillium dahliae
... RNA-Seq is a useful method for revealing the tran- scriptional changes in eukaryotes (Cloonan et al. 2008; Metzker 2009; Davidson et al. 2012), and it is also an ef- ficient tool for improving the gene models, ...
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Interactions between Melanin Enzymes and Their Atypical Recruitment to the Secretory Pathway by Palmitoylation
... all melanin enzymes trafficking to/through endosomes provides a plausible explanation for the subcellular compartmentalization of melanin biosynthesis and trafficking in secretory endosomes in ...
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Adenylyl Cyclase-Associated Protein Aca1 Regulates Virulence and Differentiation of Cryptococcus neoformans via the Cyclic AMP-Protein Kinase A Cascade
... to melanin produc- tion via the Cac1-cAMP-PKA-dependent pathway. Melanin plays a role as an antioxidant during host infection and serves as a virulence factor regulated by the Gpa1-Cac1-cAMP-PKA signaling ...
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N (4 methoxyphenyl) caffeamide induced melanogenesis inhibition mechanisms
... Tyrosinase and its activity play a major role in control- ling melanogenesis [31–33]. Agents or products that inhibit tyrosinase activity have been used in skin whitening cosmetics and cosmeceuticals [1, 2, 34]. ...
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Journal of Applied Pharmaceutical Science
... in melanin biosynthesis assays using B16 melanoma ...In melanin formation inhibition assay, luteolin -7-O--glucoside showed the inhibitory activity in a dose-dependent manner and reach 44% of ...
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Evaluation of melanogenesis in A-375 melanoma cells treated with 5,7-dimethoxycoumarin and valproic acid
... of melanin biosynthesis taking place in specialized cells called ...of melanin: black and brown eumelanins, which are insoluble in alkaline solutions, and yellow or orange pheomelanin, which are ...
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Proteomic changes associated with deletion of the Magnaporthe oryzae conidial morphology-regulating gene COM1
... of melanin between cell wall and plasma membrane of appressoria produced by the Δcom1 mutant (Figure ...the melanin layer of mature appressoria, which had reduced accumulation of ...melanin. ...
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Phosphopantetheinyl transferase (Ppt)-mediated biosynthesis of lysine, but not siderophore or DHN melanin, is required for virulence of Zymoseptoria tritici on wheat
... lysine biosynthesis and the activities of non-ribosomal peptide synthases (NRPS) and polyketide synthases ...lysine biosynthesis, NRPS-based siderophore production and PKS-based DHN melanin ...
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Phosphopantetheinyl transferase (Ppt)-mediated biosynthesis of lysine, but not siderophore or DHN melanin, is required for virulence of Zymoseptoria tritici on wheat
... lysine biosynthesis and the activities of non-ribosomal peptide synthases (NRPS) and polyketide synthases ...lysine biosynthesis, NRPS-based siderophore production, and PKS-based DHN melanin ...
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Melanin-embedded materials effectively remove hexavalent chromium (CrVI) from aqueous solution
... by melanin beads was evaluated for the following set conditions: pH of 2, shaking rate of 200 rpm at 30 °C, solid/liquid ratio of 20 g/L, and sorp- tion time of 2 h for IMB or 4 h for ...
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STUDY ON EXTRACTION OF CEPHALOPOD’S INK FOR DYEING OF TEXTILE MATERIALS
... Finally, melanin is used in cosmetics to fade defects of the skin diseases called ...of melanin to plastics has enabled the production of sunglasses with a high ability to block UV ...
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