Melanoma cell lines
A synthetic peptide inhibitor for alpha chemokines inhibits the growth of melanoma cell lines
... serum-independent melanoma cell growth in vitro ...I, melanoma cell lines produced IL-8 in z 10 times higher concentration than ...to melanoma cells may be ex- plained by there ...
8
Functional features of cancer stem cells in melanoma cell lines
... specific cell subsets from clinical specimens, which have been identified in different types of tumors, including melanoma ...established cell lines to identify cell subsets endowed ...
14
Chemopreventive Potential of Centella Asiatica on B6F10 Melanoma Cell Lines In Experimental Mice
... Aqueous extract of Centella asiatica was investigated at different dose rates 500 and 1000mg/kg body weight against B6F10 melanoma cell lines in C57BL hybrid mice. The inhibition of growth of the ...
11
CYTOKINE AND GROWTH FACTOR MODULATION OF CELL CYCLE EVENTS IN HUMAN MELANOMA CELL LINES
... of cell cycle events using the Multicycle software ...the cell cycle ...unrelated melanoma cell lines where positive values above the zero line indicate an accumulation of cells in GO/G ...
10
Cryptotanshinone has diverse effects on cell cycle events in melanoma cell lines with different metastatic capacity
... the cell cycle effect of CTs in vivo also requires further ...on cell cycle events in melanoma cell lines with different metastatic capacity, offers a useful tool to investigate the ...
19
Effects of CT-Xp Gene Knock down in Melanoma Cell Lines
... the melanoma cell line ...malignant melanoma, breast carcinoma, bladder carcinoma, lung carcinoma, liver carcinoma, thyroid carcinoma, mesothelioma and germinal cell cancers ...in ...
11
Differential sensitivity of melanoma cell lines with BRAFV600Emutation to the specific Raf inhibitor PLX4032
... sensitive cell lines, four were highly sensitive with IC 50 values below 1 μM, and three were moderately sensitive with IC 50 values between 1 and 10 ...and cell cycle arrest in both sensitive and ...
11
Pathway landscapes and epigenetic regulation in breast cancer and melanoma cell lines
... The analysis of the list of the significantly deregulated genes is based on the F-Census database [17] (http://210.46.85.180:8080/fcensus/) in order to extract information from highly inconsistent cancer gene data ...
16
Mitochondrial oxidative phosphorylation controls cancer cell’s life and death decisions upon exposure to MAPK inhibitors
... apoptotic cell death induced by vemurafenib or ...increased cell death in A375 and SKMEL28 cells treated with vemurafenib or thapsigargin (Figures 4E–4F and ...vemurafenib-induced cell death in ...
13
Bioenergetic modulation with dichloroacetate reduces the growth of melanoma cells and potentiates their response to BRAFV600E inhibition
... and cell death in melanoma cell lines, primary human melanocytes, and BRAF V600E -mutant melanoma cells with acquired resist- ance to ...
12
Inhibition of Pannexin 1 reduces tumorigenic properties of human melanoma
... in cell migration of human melanoma cell lines may occur from direct modulation of actin by ...BL6 melanoma cells, and have been shown to be characteristic of a more melanocytic-like ...
103
Activation of Notch1 signaling is required for β catenin–mediated human primary melanoma progression
... primary melanoma cells when compared with GFP-trans- fected (Figure 5A) and nontransfected cell ...metastatic melanoma cell lines, suggesting a stage-specific effect of Notch signaling ...
12
Lunasin is a novel therapeutic agent for targeting melanoma cancer stem cells
... that melanoma is initiated and maintained by a small population of malignant cells called cancer-initiating cells (CICs) that exhibit stem-cell-like ...in melanoma tumor cell ...human ...
14
Analysis of gene expressions in both melanoma and melanocyte cell lines by chip-seq technology
... and melanoma in human cell lines, ChIP-seq data were retrieved from two public domain databases such as Array Express and ...and melanoma cell lines ...and melanoma cells ...
8
Metformin and trametinib have synergistic effects on cell viability and tumor growth in NRAS mutant cancer
... mutant melanoma cell lines DO4, MM415, MM485, SK-MEL-2, MaMel30I and MaMel27II were a generous gift from Boris Bastian at the University of California, San Francisco (UCSF); cell lines ...
10
RASSF8 regulates progression of cutaneous melanoma through nuclear factor-κb
... cutaneous melanoma; however the functional role of RASSF8 in melanoma is not ...in melanoma cell lines and tumors of different AJCC ...metastatic melanoma lines and ...
13
Antisense oligonucleotide–mediated MDM4 exon 6 skipping impairs tumor growth
... human melanoma cell lines and in melanoma patient– derived xenograft (PDX) mouse models, antisense oligonucleotide–mediated (ASO-mediated) skipping of exon 6 decreased MDM4 abundance, ...
18
Orally administered endoxifen inhibits tumor growth in melanoma-bearing mice
... With the growth in understanding of the importance of cytochrome P450 2D6 (CYP2D6) polymorphism and its relationship with the therapeutic outcome of tamoxi- fen in patients with breast cancer [6], we can now partly ...
7
Activating PIK3CA mutations coexist with BRAF or NRAS mutations in a limited fraction of melanomas
... four melanoma cell lines carrying constitutive differences in mutational status of both BRAF and PIK3CA genes (including the only two cell lines with coexistence of BRAF and PIK3CA ...
7
Differential chemosensitivity to antifolate drugs between RAS and BRAF melanoma cells
... of melanoma cells to chemo- therapeutic agents, we tested three different classes of DNA damaging agents: carmustine, cisplatin and DTIC in 9 NRAS mutant and 9 BRAF mutant melanoma cell lines ...
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