Membrane Fusion
Palmitoylation Contributes to Membrane Curvature in Influenza A Virus Assembly and Hemagglutinin-Mediated Membrane Fusion
... complete fusion products with lipo- ...virus-driven fusion interme- diates ...HA-mediated membrane fusion in a system that more closely mimics influenza virus fusion, we used ...cell-RBC ...
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Vaccinia Virus L1 Protein Is Required for Cell Entry and Membrane Fusion
... and fusion (6); and (iii) L1 has intramolecular disulfide bonds formed by the poxvirus cytoplasmic redox system (32), and the other known substrate proteins all have roles in entry and membrane ...
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An Epitope of the Semliki Forest Virus Fusion Protein Exposed during Virus-Membrane Fusion
... The decreased MAb E1a-1 binding observed with SFV 1-8 and SFV 4-2 could be a direct consequence of amino acid changes in the MAb binding site or an indirect effect of a lack of response of the spike protein to low pH or ...
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Proteolytic Cleavage of the Fusion Protein but Not Membrane Fusion Is Required for Measles Virus-Induced Immunosuppression In Vitro
... mediate membrane fusion during viral entry and spread (17, ...origin, fusion-mediated loss of RC is unlikely to contribute to MV-induced immuno- suppression in our system, since (i) adherent cells of ...
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Role of the Hemagglutinin-Neuraminidase Protein in the Mechanism of Paramyxovirus-Cell Membrane Fusion
... for fusion promotion ...brane fusion through a specific interaction with F ...investigated fusion promotion activity by characterizing NDV HN mutants and comparing their biological activities to ...
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Identification of a membrane fusion domain and an oligomerization domain in the baculovirus GP64 envelope fusion protein.
... envelope fusion protein (GP64 EFP) is the major envelope glycoprotein of the budded virion and has been shown to mediate acid-triggered membrane fusion both in virions and when expressed alone in ...
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Affinity Thresholds for Membrane Fusion Triggering by Viral Glycoproteins
... by membrane fusion. This is mediated by viral membrane glycoproteins whose af- finities for their receptors vary widely from the millimolar range ...to membrane fusion, thereby ...
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A Histidine Switch in Hemagglutinin-Neuraminidase Triggers Paramyxovirus-Cell Membrane Fusion
... is membrane fusion. The fusion requires a coordinated action of two envelope gly- coproteins: a receptor-binding protein, hemagglutinin-neur- aminidase (HN), and a fusion protein F ...cell ...
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Pseudorabies Virus Glycoprotein M Inhibits Membrane Fusion
... investigate membrane fusion mediated by pseudo- rabies virus (PrV) ...cell fusion was quantitated 27 to 42 h after ...HSV-1, fusion was also observed when the gD-encoding plasmid was omitted, ...
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Length Requirements for Membrane Fusion of Influenza Virus Hemagglutinin Peptide Linkers to Transmembrane or Fusion Peptide Domains
... for fusion activity, there are likely to be additional constraints on the lengths of these domains with regard to virus ...to membrane fusion activity, the observation that insertions and deletions ...
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Cell-based analysis of Chikungunya virus E1 protein in membrane fusion
... cell fusion assay found that those cells infected by CHIKV E1-H230A mutant baculovirus showed little fusion activity, and those bearing CHIKV E1-G91D mutant completely lost the ability to induce cell-cell ...
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The cytoplasmic domain of the gamete membrane fusion protein HAP2 targets the protein to the fusion site in Chlamydomonas and regulates the fusion reaction
... Cell-cell fusion between gametes is a defining step during development of eukaryotes, yet we know little about the cellular and molecular mechanisms of the gamete membrane fusion ...after ...
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The Heptad Repeat C Domain of the Respiratory Syncytial Virus Fusion Protein Plays a Key Role in Membrane Fusion
... where fusion-increasing mutations localized to the solvent-exposed face of the HRC helix and fusion-decreasing and ablating muta- tions located to residues on the side of the helix that is buried in the F ...
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Oligomerization-dependent folding of the membrane fusion protein of Semliki Forest virus.
... the membrane proteins, including the small 6K peptide, are sepa- rated from each other by the host signal peptidase (1, 4, 6, 8, 19, 27, 29, 31, 32, 39, 46, ...larger, membrane-bound part (E2) ...the ...
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Mechanisms of membrane fusion
... its fusion peptide (Daniels et ...adjacent fusion peptides (Stegmann et a l , 1987; Junankar & Cherry, ...between fusion peptides offers a feasible molecular explanation for this virus ...
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Membrane fusion triggers rapid degradation of two gamete specific, fusion essential proteins in a membrane block to polygamy in Chlamydomonas
... for fusion, yet, once fusion occurs, in many organisms the new zygote becomes incapable of further membrane fusion ...of fusion capacity (block to polygamy) remain ...gamete-specific ...
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Probing the Flavivirus Membrane Fusion Mechanism by Using Monoclonal Antibodies
... internal fusion peptide (FP) ...flavivirus membrane fusion, as depicted in ...during fusion concern the relocation of DIII and the stem: DIII moves from its original position at the end of the ...
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Effects of Photobleaching on Membrane Fusion and Infectivity of Dye Labeled Sindbis Virus
... in membrane fusion has been ...viral fusion was not altered by photobleaching, we suggest that the loss of infectivity can be attributed to damage of the viral ...
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The Unique Transmembrane Hairpin of Flavivirus Fusion Protein E Is Essential for Membrane Fusion
... double membrane anchor is a unique structural feature not found in other viral fusion proteins, it was the objective of our work to study the contributions of these sequence elements to the different stages ...
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Mutational Analysis of the Zippering Reaction during Flavivirus Membrane Fusion
... and fusion protein (reviewed in reference ...flavivirus membrane fusion has been developed ...viral membrane, as suggested by cryo-EM studies using West Nile virus and mono- clonal antibody ...
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