Membrane vesicle
Persisting Immune Responses Indicating Long-Term Protection after Booster Dose with Meningococcal Group B Outer Membrane Vesicle Vaccine
... outer membrane vesicle (OMV) vaccine, Men- ...outer membrane proteins in the form of vesicles and is prepared from a clinical isolate repre- sentative of that epidemic ...
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Membrane Distribution of the Pseudomonas Quinolone Signal Modulates Outer Membrane Vesicle Production in Pseudomonas aeruginosa
... outer membrane vesicle (OMV) ...outer membrane, causing expansion of the outer leaflet and consequently inducing ...outer membrane before it can initiate OMV ...inner membrane, which ...
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Cellular Immune Responses in Humans Induced by Two Serogroup B Meningococcal Outer Membrane Vesicle Vaccines Given Separately and in Combination
... MenBvac and MeNZB are safe and efficacious outer membrane vesicle (OMV) vaccines against serogroup B meningococcal dis- ease. Antibody responses have previously been investigated in a clinical trial with ...
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Combined Administration of Meningococcal Serogroup B Outer Membrane Vesicle Vaccine and Conjugated Serogroup C Vaccine Indicated for Prevention of Meningococcal Disease Is Safe and Immunogenic
... MenBvac and Menjugate are safe and efficacious vaccines. The purpose of this study was to evaluate safety and immunogenicity of the combination (MenB/C) of the lyophilized active components of the conjugated group C ...
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Immunogenicity and Safety of Three Doses of a Bivalent (B:4:P1.19,15 and B:4:P1.7-2,4) Meningococcal Outer Membrane Vesicle Vaccine in Healthy Adolescents
... An experimental bivalent meningococcal outer membrane vesicle (OMV) vaccine (B:4:P1.19,15 and B:4: P1.7-2,4) has been developed to provide wide vaccine coverage particularly of the circulating strains in ...
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A Burkholderia pseudomallei Outer Membrane Vesicle Vaccine Provides Protection against Lethal Sepsis
... outer membrane vesicles (OMVs) derived from ...cell membrane (15). The process of extracellular membrane vesicle secretion is conserved among Gram-negative and Gram- positive bacteria, ...
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Seroprevalence of Bactericidal and Anti-Outer Membrane Vesicle Antibodies to Neisseria meningitidis Group B in England
... Outer membrane vesicle (OMV) and recombinant protein-based vaccines targeted against multiple strains of group B meningococci are under development. The serum bactericidal antibody (SBA) assay has been ...
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A Critical Threshold of Meningococcal Factor H Binding Protein Expression Is Required for Increased Breadth of Protective Antibodies Elicited by Native Outer Membrane Vesicle Vaccines
... outer membrane vesicle (dOMV) vaccines are proven to be effective for prevention of group B disease, and these vaccines were used to control meningococcal group B epi- demics in Cuba (35), Norway (5, 6), ...
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Sodium taurocholate stimulates Campylobacter jejuni outer membrane vesicle production via down-regulation of the maintenance of lipid asymmetry pathway
... outer membrane vesicles (OMVs) contain numerous virulence- associated proteins including the cytolethal distending toxin and three serine ...outer membrane component of the MLA pathway significantly ...
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Mesenchymal stromal cell-derived nanovesicles ameliorate bacterial outer membrane vesicle-induced sepsis via IL-10
... outer membrane vesicles (OMVs) [22, 23], which distribute many virulent factors systemically, including lipopolysaccharides (LPS), lipoproteins, and genetic ...
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Engineered outer membrane vesicle is potent to elicit HPV16E7-specific cellular immunity in a mouse model of TC-1 graft tumor
... OMVs increased, the fluorescence intensity of the cells and the ratio of positive cells augmented. Similarly, Dio-labeled OMVs exhibited fluorescence in cells, revealing that the OMVs themselves were internalized ...
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Development of a thermostable spray dried outer membrane vesicle pertussis vaccine for pulmonary immunization
... To determine whether the (spray dried) omvPV induced mucosal immune responses after pulmonary immunization, anti-OMV IgA-se- creting cells, IgA-producing memory B-cells and IgA antibody responses were assessed before ...
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Mycobacterium tuberculosis Pst/SenX3 RegX3 Regulates Membrane Vesicle Production Independently of ESX 5 Activity
... of membrane vesicles by the ⌬ pstA1 mutant requires ...the vesicle fraction from the ΔpstA1 ΔregX3 mutant but at reduced levels compared to those in the ΔpstA1 strain ...
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Effectiveness of a Group B outer Membrane Vesicle Meningococcal Vaccine in Preventing Hospitalization from Gonorrhea in New Zealand: a Retrospective Cohort Study
... outer membrane vesicles (OMV) vaccines in Cuba,[8] New Zealand (NZ), 10 and to a limited extent, Norway [9,10], suggested that meningococcal B OMV vaccines may reduce the risk of ...
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Outer Membrane Vesicle Production Facilitates LPS Remodeling and Outer Membrane Maintenance in Salmonella during Environmental Transitions
... As vesicle production is a complex process involving numer- ous cell envelope components, additional mechanistic factors may be involved in establishing the lipid A content of released ...
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A Bilayer Couple Model of Bacterial Outer Membrane Vesicle Biogenesis
... a membrane stress response in Escherichia coli (24), most Gram-negative bacteria naturally produce OMVs while growing under perceived optimal, stress-free conditions ...the membrane (18, 40); PQS possesses ...
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Immunogenicity and Safety of a Combination of Two Serogroup B Meningococcal Outer Membrane Vesicle Vaccines
... After the booster dose the proportions of subjects with SBA titers of ⱖ 4 against strain 44/76 ranged from 67% in the group receiving three doses of MeNZB plus one dose of MenBvac to 85%[r] ...
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High dissolved oxygen tension triggers outer membrane vesicle formation by Neisseria meningitidis
... outer membrane of the bacteria, it is generally thought that the release of vesicles is not a random process ...outer membrane to the pep- tidoglycan layer, or O-antigen charge ...
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Liposomes encapsulating polymeric chitosan based vesicles - a vesicle in vesicle system for drug delivery
... Freeze fracture electron microscopy was used to visualise both the gold-labelled polymeric vesicles, the gold-labelled vesicle in vesicle system and egg PC liposomes. Specimens were fast-frozen by plunging ...
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Phosphatidylinositol-4,5-Bisphosphate and Phospholipase D-Generated Phosphatidic Acid Specify SNARE-Mediated Vesicle Fusion for Prospore Membrane Formation
... either vesicle SNAREs (v-SNAREs) or target membrane SNAREs (t-SNAREs), ...incoming vesicle approaches its target membrane, the v-SNAREs and t-SNAREs assemble via their SNARE domains into a ...
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