Merozoite surface proteins
Binding of Plasmodium falciparum merozoite surface proteins DBLMSP and DBLMSP2 to human immunoglobulin M is conserved amongst broadly diverged sequence variants.
... both proteins from the ...falciparum proteins (20). Both proteins were expressed ...DBL-containing merozoite surface proteins (EBA140, EBA175, EBA181) reacted, as expected, with ...
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Optimization and validation of multi coloured capillary electrophoresis for genotyping of Plasmodium falciparum merozoite surface proteins (msp1 and 2)
... the merozoite surface proteins 1 and 2 (msp1 and msp2) is well established in the field of malaria research to determine the number and types of concurrent clones in an ...
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Polymorphism in two merozoite surface proteins of Plasmodium falciparum isolates from Gabon
... A multi-immune response approach Washington, D.C.: ASM Press 1996, 77104 Smythe JA, Coppel RL, Brown GV, Ramasamy R, Kemp DJ and Anders RF Identification of two integral membrane protein[r] ...
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Heterogeneous genetic diversity pattern in Plasmodium vivax genes encoding merozoite surface proteins (MSP) 7E, −7F and 7L
... encoding proteins lar- ger than 300 amino ...(12 proteins) and Plasmodium knowlesi (5 proteins) MSP-7 se- quences using the MUSCLE algorithm ...
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Genetic polymorphism of merozoite surface proteins 1 and 2 of Plasmodium falciparum in the China–Myanmar border region
... Genetic diversity of the parasites provides useful infor- mation on the parasite populations and control efforts against malaria. Polymorphic genetic markers of P. fal- ciparum include the merozoite surface ...
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Extensive diversity in the allelic frequency of Plasmodium falciparum merozoite surface proteins and glutamate rich protein in rural and urban settings of southwestern Nigeria
... parasite proteins under consideration as potential vaccine candidates, either individually or in combination with other para- site proteins, because of their preponderance at various stages of the parasite ...
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A novel Pfs38 protein complex on the surface of Plasmodium falciparum blood stage merozoites
... six proteins of Pfs38 protein complex and co-localization studies, provided additional evidence for the existence of such a ...by surface plasmon resonance (SPR) analysis in the present ...ite ...
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Serological detection of Plasmodium vivax malaria using recombinant proteins corresponding to the 19 kDa C terminal region of the merozoite surface protein 1
... binant proteins representing the ...recombinant proteins containing the C-terminal region of ...recombinant proteins based on the sequence of other blood stage antigens of ...vivax Merozoite ...
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Identification and characterization of Pv50, a novel Plasmodium vivax merozoite surface protein
... and merozoite surface proteins in native ...with merozoite surface protein(s), fluorescence intensi- ties observed using the Cy5 channel from the simulta- neous activity and binding ...
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Genetic polymorphism of merozoite surface protein 1 and merozoite surface protein 2 in Plasmodium falciparum isolates from Brazzaville, Republic of Congo
... The present study was aimed at analysing genetic diversity of Plasmodium falciparum merozoite surface proteins 1 and 2 MSP-1 and MSP-2 and to determine the multiplicity of infection in c[r] ...
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Effect of treating Schistosoma haematobium infection on Plasmodium falciparum specific antibody responses
... the antigens and may be indicating the previously pub- lished shift from IgG1 to IgG3 responses directed against merozoite surface proteins [37]. Given the mesondemic transmission patterns of the ...
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Genetic diversity of the merozoite surface protein 3 gene in Plasmodium falciparum populations in Thailand
... antigenic proteins that are highly expressed on, or associated with, the surface of merozo- ites, such as the merozoite surface proteins ...
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Diversity and evolutionary genetics of the three major Plasmodium vivax merozoite genes participating in reticulocyte invasion in southern Mexico
... In SMX, the highest nucleotide diversity (π) was for msp1 42 , followed by ama1 I-II and finally dbp II (Table 1). Fig. 2 Haplotype networks of P. vivax genes encoding merozoite surface proteins in ...
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Malaria Parasite Survival Depends on Conserved Binding Peptides' Critical Biological Functions
... RBC surface deformation (originally weak, later becoming very strong) (Figures 1F and H), ...(DRM) proteins, Pf12 and Pf38 are GPI anchored, this being a very common characteristic of Mrz-derived ...
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Plasmodium falciparum merozoite surface protein 1: Antigenicity, immunogenicity and structure.
... mutant proteins is ...other surface proteins that are involved during erythrocyte invasion by the ...other proteins on the merozoite surface can not be ruled ...the ...
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Antibody responses to P falciparum blood stage antigens and incidence of clinical malaria in children living in endemic area in Burkina Faso
... MSP3 and GLURP have been tested in malaria vaccine antigens that have already undergone phase 1 trials. The efficacies of these malaria vaccines will be tested in phase II and III vaccine trials in Africa. For the ...
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Behaviour of fat globules and membrane proteins under different processing environments as related to milk powder manufacture : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Food Technology
... Fig. 4.5 shows the polypeptide patterns of heated washed cream, as determined by SDS p AGE under non-reducing conditions. It was observed that the material that remained on the top or had just migrated into the ...
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Antibody response against three Plasmodium falciparum merozoite antigens in Mamuju District, West Sulawesi Province, Indonesia
... various merozoite proteins have been implicated in the erythrocyte invasion, and some of these have been identified as targets for vac- cine development and markers for epidemiologic studies ...to ...
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Multiplicity and molecular epidemiology of Plasmodium vivax and Plasmodium falciparum infections in East Africa
... Background: Parasite genetic diversity and multiplicity of infection (MOI) affect clinical outcomes, response to drug treatment and naturally‑acquired or vaccine‑induced immunity. Traditional methods often underestimate ...
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Asexual expansion of Toxoplasma gondii merozoites is distinct from tachyzoites and entails expression of non-overlapping gene families to attach, invade, and replicate within feline enterocytes
... we identified 11 “tachyzoite-specific” and 7 “merozoite- specific” genes based on >8-fold difference in mRNA ex- pression within this subset (Additional file 2: Figure S2), there is little evidence in our data ...
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