Mesenchymal Multipotent Stromal Cells (MMSC)
Hierarchy of mesenchymal stem cells: Comparison of multipotentmesenchymal stromal cells with fibroblast colony forming units
... stem cells is still obscure. Two types of human stromal precursor cells are ...system: mesenchymal multipotent stromal cells (MMSC) and fibroblast colony forming ...
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The therapeutic potential of three-dimensional multipotent mesenchymal stromal cell spheroids
... Previously, it was demonstrated that intravenously in- fused MSCs are trapped in the lungs as micro emboli, with subsequent activation of anti-inflammatory TNFα- stimulated gene/protein 6 (TSG-6) secretion after 12–24 ...
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Multipotent stromal cells/mesenchymal stem cells and fibroblasts combine to minimize skin hypertrophic scarring
... transplanted cells experience is the low nutrient and hypoglycemic environment that can in- duce apoptosis ...transplanted cells in these conditions, and the protective effect of TNC combined with HA-gel, ...
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Cytoplasmic-targeted parvalbumin blocks the proliferation of multipotent mesenchymal stromal cells in prophase
... Introduction: Multipotent mesenchymal stromal cells (MSCs) have gained considerable interest because of their potential use in the treatment of a variety of diseases and ...of cells ...
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Mesenchymal stem cells/multipotent stromal cells (MSCs) are glycolytic and thus glucose is a limiting factor of in vitro models of MSC starvation
... the cells in culture while metabolic analyses of the MSCs showed a relatively high glycolytic ...of mesenchymal stem cells, with a high dependence on glycolysis and glucose metabolism [11, ...the ...
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Human mesenchymal stem cells/multipotent stromal cells consume accumulated autophagosomes early in differentiation
... the cells produce a more robust adipogenic dif- ferentiation over the course of 30 ...the cells from immediately cycling autopha- gosomes as they normally do may in fact allow the ...
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The mesenchymal stem cells in multiple sclerosis (MSCIMS) trial protocol and baseline cohort characteristics: an open label pre test: post test study with blinded outcome assessments
... MSC: Mesenchymal Stem Cell / Multipotent mesenchymal stromal cell; MSCIMS: The mesenchymal stem cells in multiple sclerosis trial; MSFC: Multiple sclerosis functional composite ...
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Intravitreal administration of multipotent mesenchymal stromal cells triggers a cytoprotective microenvironment in the retina of diabetic mice
... glial cells, and that visual deficits in the early stage of DR are correlated with retinal neurosensory dysfunction that is mainly related to the early loss of RGCs [8, ...beta cells, allowing the ...
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Placenta-derived multipotent mesenchymal stromal cells: a promising potential cell-based therapy for canine inflammatory brain disease
... When cells were approximately 70% confluent, they were trypsinized and resuspended in standard medium supplemented with L- tryptophan (Sigma-Aldrich) to a final concentration of 600 ...
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HLA-DR expression in clinical-grade bone marrow-derived multipotent mesenchymal stromal cells: a two-site study
... + cells gradually decreased over ...on cells during expansion cultures is variable over time; how- ever, in-process and final product quality controls are per- formed only at specific time points during the ...
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Human adult stem cells derived from adipose tissue and bone marrow attenuate enteric neuropathy in the guinea-pig model of acute colitis
... stem cells (MSCs) otherwise known as multipotent stromal cells have been proposed as a potential treatment option for chronic inflammation and neurological damage ...These cells are ...
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Allogeneic Guinea pig mesenchymal stem cells ameliorate neurological changes in experimental colitis
... decade, mesenchymal stem cells (MSCs), also known as multipotent stromal cells, have emerged as a clinically viable therapy for many diseases, includ- ing IBD ...
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Regenerative medicine in the treatment of idiopathic pulmonary fibrosis: current position
... specifically mesenchymal stem cells (MSCs), a multipotent stromal cell population, which have demonstrated promising data in multiple animal models of pulmonary fibrosis ...the cells ...
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Cryopreservation of canine cardiosphere-derived cells: Implications for clinical application
... differentiation, cells were fixed in 4% PFA for 10 min then blocked and permeabilized in protein block solution (DAKO) containing 1% saponin (Sigma- Aldrich) for ...h. Cells were incubated at 4°C with a ...
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Decellularized silk fibroin scaffold primed with adipose mesenchymal stromal cells improves wound healing in diabetic mice
... the mesenchymal markers CD146 (Figure 1E) and CD44 (Figure 1F) and for the integrin CD49d (Figure ...1G). Cells seeded on patches confirmed their negativity for the hematopoietic marker CD45 (Figure ...
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Comparative analysis of curative effect of bone marrow mesenchymal stem cell and bone marrow mononuclear cell transplantation for spastic cerebral palsy
... This study concludes, in terms of gross motor function, 3 months after transplantation, the BMMSC group and the BMMNC group begin to gain significant improve- ments (A, B, and C dimensions and GMFM total scores). These ...
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First-in-man intravenous implantation of stromal vascular fraction in psoriasis: a case study
... The stromal vascular fraction (SVF) is a mixture of cells including the MSCs with the adipocyte or fat cell population depleted or ...of cells that express the protein CD34, which is known to be ...
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Search | Preprints
... Bone marrow-derived mesenchymal stem cells (BM-MSCs) are the most frequently investigated cell type in atherosclerosis and related diseases. Dr. Fang et al. found that allogeneic BM-MSCs transplantation can ...
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Are mesenchymal stromal cells immune cells?
... immune cells? If one looks in detail at the immunological effects that are induced by the infusion of MSCs, it can be observed that MSCs induce small inflammatory responses shortly after infusion [69], whereas it ...
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Chondrogenic induction of mesenchymal stromal/stem cells from Wharton’s jelly embedded in alginate hydrogel and without added growth factor: an alternative stem cell source for cartilage tissue engineering
... and cell commitment to a differentiation pathway. In our study, after 14 days of 3D culture, WJ-MSC and BM-MSC showed different phenotype profiles. WJ-MSC positivity for mesenchymal markers seemed to decrease ...
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