Metabolic fluxes
Metabolic fluxes-oriented control of bioreactors: a novel approach to tune micro-aeration and substrate feeding in fermentations
... genome-scale metabolic models (GSMs) can also be employed for bioreactor ...extracellular fluxes of metabolites at steady-state for different environmental conditions, considering the inlet fluxes of ...
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Staphylococcus aureus Coordinates Leukocidin Expression and Pathogenesis by Sensing Metabolic Fluxes via RpiRc
... a metabolic sensor-regulator, RpiRc, is a potent and selective repressor of two leukocidins, LukED and ...altered metabolic fluxes in the tri- carboxylic acid cycle, glycolysis, and amino acid ...
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of metabolic fluxes in Saccharomyces cerevisiae during
... Keywords: Flux Balance Analysis, Saccharomyces cerevisiae, Tequila, fermentation, higher alcohols.. Introduction 30.[r] ...
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Modeling Neisseria meningitidis metabolism: from genome to metabolic fluxes
... specific metabolic rates and the corresponding measurement variances used in flux balance analysis (FBA) were calculated using Monte Carlo Simulation (MCS) with the measured experimental data and their standard ...
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Integrated analysis of gene expression and metabolic fluxes in PHA-producing Pseudomonas putida grown on glycerol
... is about sixteen times lower than that of other bacteria, such as Escherichia coli, which provides a great advantage to use this substrate commercially. The shift from carbon (glycerol) to nitrogen (ammonium) limitation ...
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Systems level mapping of metabolic complexity in Mycobacterium tuberculosis to identify high value drug targets
... of metabolic persister genes (MPGs) and identified a spectrum of such genes that can probably give rise to persister phe- notypes of Mtb and hence may be responsible for drug ...of metabolic fluxes ...
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Integrated human virus metabolic stoichiometric modelling predicts host based antiviral targets against Chikungunya, Dengue and Zika viruses
... compare fluxes from the host metabolic system optimized for either host maintenance or viral ...how metabolic fluxes in a host might shift with virus ...measured metabolic flux changes ...
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Insights into metabolic osmoadaptation of the ectoines-producer bacterium Chromohalobacter salexigens through a high-quality genome scale metabolic model
... The above data show that the iFP764 model is coherent and reproduces the major metabolic features of C. salexi- gens. However, FBA can only generate a single flux dis- tribution corresponding to maximal growth ...
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Metabolic pathway analysis for in silico design of efficient autotrophic production of advanced biofuels
... by metabolic pathway analysis tools, specifically elementary mode analysis (EMA) and flux balance analysis ...cell’s metabolic flux profiles and its phenotypic spaces for the autotrophic production of ...
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Identification of In Vivo Enzyme Activities in the Cometabolism of Glucose and Acetate by Saccharomyces cerevisiae by Using 13C-Labeled Substrates
... strain with the corresponding gene deleted was grown under the same conditions. The labeling patterns of protein- ogenic amino acids were analyzed and used to estimate metabolic fluxes and/or make ...
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Elucidation of the roles of adhE1 and adhE2 in the primary metabolism of Clostridium acetobutylicum by combining in-frame gene deletion and a quantitative system-scale approach
... and metabolic fluxes, and butanol production was completely ...thus metabolic fluxes were redirected toward butyrate ...acidogenesis, metabolic fluxes were not significantly ...
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In silico reconstruction and experimental validation of Saccharopolyspora erythraea genome-scale metabolic model iZZ1342 that accounts for 1685 ORFs
... genome-scale metabolic reconstructions (GSMRs) of ...the metabolic reactions of ...lacking metabolic pathways need to be filled; thirdly, the gene-protein- reactions (GPRs) relationship should be ...
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Metabolic flux responses to genetic modification for shikimic acid production by Bacillus subtilis strains
... several microorganisms, particular Escherichia coli, for SA accumulation [6-9]. One strategy was to increase the supply of PEP and/or E4P, thus more carbon substrate channeled into SA synthesis. For examples, the PEP- ...
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Dominance, Pleiotropy and Metabolic Structure
... T h e measurement of these rates-the metabolic fluxes- and of the metabolite pool concentrations is the proper subject of ‘quantitative metabolism.’ T h e methodolo[r] ...
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Metabolic flux and transcriptional analysis elucidate higher butanol/acetone ratio feature in ABE extractive fermentation by Clostridium acetobutylicum using cassava substrate
... The metabolic flux and (key enzymes) genes transcriptional analysis indicated that weakened metabolic fluxes in organic acids (especially butyrate) formation and re-assimilation pathways, which ...
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Biotic pump of atmospheric moisture as driver of the hydrological cycle on land
... transpiration fluxes via stomata opening/closure, regulation of the vertical temper- ature gradient below the canopy, facilitation of precipitation by biogenic aerosols, and other unknown processes, of which some ...
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Turbulent flux modelling with a simple 2 layer soil model and extrapolated surface temperature applied at Nam Co Lake basin on the Tibetan Plateau
... to fluxes from the modified and original Hybrid and COARE are fluxes from the lake derived by TOGA-COARE whereas SEWAB is a SVAT model and HM refers to a hydrodynamic multi-layer lake model after Foken ...
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Fluxes of Gaseous Elemental Mercury at a Mediterranean Coastal Grassland
... GEM fluxes for all the months during the day is represented in Figure 1, along with the rain events that happen in each ...GEM fluxes that are related to rain events and measured right before or during the ...
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Scattering kernel for polyatomic molecules
... various fluxes at the wall, namely: the fluxes of the three components of the momentum and the fluxes of the rotational and vibrational energies of ...
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Integrated Modeling of Whole Tokamak Plasma
... and density are also reduced by the reduction of fluxes and then gradually increase by the recovery of fluxes. The above evolution of profiles inside the separatrix, temper- ature and de[r] ...
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