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metabolism and excretion.

Leptocephalus energetics: metabolism and excretion

Leptocephalus energetics: metabolism and excretion

... in excretion can be divided into two subcomponents: feces, the portion of ingested energy that is indigestible, and nonfecal nitrogen, which in fishes is usually in the form of ammonia or ...

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Excretion and metabolism of catecholamines by the isolated perfused rat kidney

Excretion and metabolism of catecholamines by the isolated perfused rat kidney

... by metabolism as well as excretion in the ...Preferential excretion and metabolism of epinephrine were confirmed in double-label experiments in which [14C]epinephrine and [3H]norepinephrine ...

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Metabolism and Excretion of Intravenous, Radio-Labeled Amisulpride in Healthy, Adult Volunteers

<p>Metabolism and Excretion of Intravenous, Radio-Labeled Amisulpride in Healthy, Adult Volunteers</p>

... fecal excretion seen with oral amisulpride, a 10 mg IV dose of amisulpride in a patient with severe renal impairment may be expected to deliver a total exposure well below the 8800 ...

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Metabolism and Excretion of Exogenous Thyrotropin Releasing Hormone in Humans

Metabolism and Excretion of Exogenous Thyrotropin Releasing Hormone in Humans

... To study the metabolism of thyrotropin-releasing hormone (TRH) in vivo, 400 µg TRH was administered intravenously to eight normal male subjects. Multiple plasma and urine samples were obtained before and after TRH ...

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High-throughput virtual screening with e-pharmacophore and molecular simulations study in the designing of pancreatic lipase inhibitors

High-throughput virtual screening with e-pharmacophore and molecular simulations study in the designing of pancreatic lipase inhibitors

... Materials and methods: High-throughput virtual screening combined with e-pharmacophore screening and ADME (absorption, distribution, metabolism, and excretion) and PAINS (pan- assay int[r] ...

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STUDIES IN STEROID METABOLISM  XIX  THE a KETOSTEROID EXCRETION PATTERN IN NORMAL MALES

STUDIES IN STEROID METABOLISM XIX THE a KETOSTEROID EXCRETION PATTERN IN NORMAL MALES

... The aqueous residue after ether extraction from Stage 2 was treated as in Method A, Stages 1, 2, 3, and 4, and a final "crude neutral fraction" was obtained.. This hydrolytic method yiel[r] ...

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In silico  investigations revealed four potential colon cancer drugs from phytochemicals in  Zingiber officinale

In silico investigations revealed four potential colon cancer drugs from phytochemicals in Zingiber officinale

... Distribution Metabolism and Excretion (ADME) compliance using an in-house database created with Traditional Chinese Medicine Systems Pharmacology database and Analysis Platform [15], Molinspiration web ...

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Tissue Distribution Study of Apocynin By RP-HPLC With UV Detector

Tissue Distribution Study of Apocynin By RP-HPLC With UV Detector

... 54 In addition to high deposition in liver and kidney, the major organs for metabolism and excretion, apocynin showed a somewhat high peak concentration and distribution in lung tissue within 15min after ...

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2. Investigating the Anti-Venom Potential of Dolichos Trilobus Root Extract: A Computational and Cheminformatics Approach 

2. Investigating the Anti-Venom Potential of Dolichos Trilobus Root Extract: A Computational and Cheminformatics Approach 

... Three compounds detected by the GC-MS analysis were analized with SwissADME to predict their absorption, distribution, metabolism and excretion (ADME) parameters, ph[r] ...

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A REVIEW ON FORMULATION APPROACHES IN IMMEDIATE RELEASE TABLET

A REVIEW ON FORMULATION APPROACHES IN IMMEDIATE RELEASE TABLET

... It is the study of absorption, distribution, metabolism and excretion. After absorption, drug attains therapeutic level and therefore elicits pharmacological effect, so both rate and extend of absorption is ...

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In vivo absorption, metabolism, and urinary excretion of alpha,beta unsaturated aldehydes in experimental animals  Relevance to the development of cardiovascular diseases by the dietary ingestion of thermally stressed polyunsaturate rich culinary oils

In vivo absorption, metabolism, and urinary excretion of alpha,beta unsaturated aldehydes in experimental animals Relevance to the development of cardiovascular diseases by the dietary ingestion of thermally stressed polyunsaturate rich culinary oils

... With the exception of direct damage to the gastrointestinal epithelium, the toxicological hazards putatively posed by alde- hydes generated from the autoxidation of PUFA-rich culinary oils are, of course, critically ...

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Find novel dual-agonist drugs for treating type 2 diabetes by means of cheminformatics

Find novel dual-agonist drugs for treating type 2 diabetes by means of cheminformatics

... distribution, metabolism, and excretion, that these novel dual agonists not only pos- sessed the same function as ragaglitazar (an investigational drug developed by Novo Nordisk for treating type 2 ...

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THE MECHANISM OF GLYCOSURIC DIURESIS IN DIABETIC MAN

THE MECHANISM OF GLYCOSURIC DIURESIS IN DIABETIC MAN

... solutions on the metabolism and excretion of water and electrolytes are not determined by the osmotic pressure of the tubular urine, but depend instead upon the metabolic and osmotic pro[r] ...

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TRACER STUDIES OF THE ABSORPTION AND FATE OF STEROID HORMONES IN MAN

TRACER STUDIES OF THE ABSORPTION AND FATE OF STEROID HORMONES IN MAN

... Comparison of oral and intravenous administration of hydrocortisone, cortisone acetate and testosterone The rapidity of absorption, metabolism and excretion of the end products of hydroc[r] ...

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IN SILICO STUDIES OF FOUR ANTHRAQUINONES OF SENNA ALATA L. AS POTENTIAL ANTIFUNGAL COMPOUNDS

IN SILICO STUDIES OF FOUR ANTHRAQUINONES OF SENNA ALATA L. AS POTENTIAL ANTIFUNGAL COMPOUNDS

... distribution, metabolism, excretion, and toxicity (ADME/T) showed us the selected anthraquinones are non-carcinogens with a positive score for blood- brain barrier and intestinal absorption (Table ...

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ETM DB: integrated Ethiopian traditional herbal medicine and phytochemicals database

ETM DB: integrated Ethiopian traditional herbal medicine and phytochemicals database

... distribution, metabolism, excretion, and toxicity; admetSAR: ADMET structure-activity relationship; AfroDB: a Select Highly Potent and Diverse Natural Product Library from African Medicinal Plants; BBB: ...

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Dogmas and controversies in the handling of nitrogenous wastes: The effect of feeding and fasting on the excretion of ammonia, urea and other nitrogenous waste products in rainbow trout

Dogmas and controversies in the handling of nitrogenous wastes: The effect of feeding and fasting on the excretion of ammonia, urea and other nitrogenous waste products in rainbow trout

... urea-N excretion, the value increases from ...aerobic metabolism increases from ~50% to ...total-N excretion is used in the calculation, there is little change in fasted fish, but the discrepancy ...

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Tryptophan metabolism in vitamin B6-deficient mice

Tryptophan metabolism in vitamin B6-deficient mice

... Tryptophan metabolism was assessed by determining the urinary excretion of tryptophan metabolites, the metabolism of It4Cjtryptophan in vivo and the formation of tryptophan and niacin m[r] ...

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THE URINARY EXCRETION OF AMINOIMIDAZOLECARBOXAMIDE IN THE LESCH-NYHAN SYNDROME

THE URINARY EXCRETION OF AMINOIMIDAZOLECARBOXAMIDE IN THE LESCH-NYHAN SYNDROME

... The increased urinary AIC excretion probably represents a reflection of the deranged purine metabolism in this syndrome and its mea- surement can be used as a screen for the Lesch- Nyhan[r] ...

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EXCRETION OF KYNURENIC ACID AND XANTHURENIC ACID DURING INFECTION

EXCRETION OF KYNURENIC ACID AND XANTHURENIC ACID DURING INFECTION

... Excretion of tryptophan metabolites in patients with a variety of disorders has been the subject of a recent review.14 Quan- titative studies of tryptophan metabolism in infected subject[r] ...

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