metastasis free survival
Novel 18 gene signature for predicting relapse in ER positive, HER2 negative breast cancer
... Abbreviations AI: Aromatase inhibitor; ATAC: Arimidex, Tamoxifen, Alone or in Combination; BCI: Breast Cancer Index; CTS: Clinical Treatment Score; DMFS: Distant metastasis-free survival[r] ...
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Involvement of hedgehog pathway in early onset, aggressive molecular subtypes and metastatic potential of breast cancer
... SMO. Following St. Gallen International Expert Consen- sus System, Pakistani cohort retains highest proportion of luminal-B (53%), followed by triple negative (18%), luminal-A(15%) and HER2 (14%) individuals. Both ...
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Molecular subtyping of nasopharyngeal carcinoma (NPC) and a microRNA-based prognostic model for distant metastasis
... The recently widely used of miRNA arrays has enabled the large scale profiling of miRNAs in NPC [23]. Here, we analyzed two independent datasets (GSE32960 and GSE70970) which consist of a total number of 558 NPC patients ...
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Sentinel lymph node excision with or without preoperative hybrid single photon emission computed tomography/computed tomography (SPECT/CT) in melanoma: study protocol for a multicentric randomized controlled trial
... Because melanoma, depending on tumor depth, me- tastasizes early into regional lymph nodes [4, 5], sentinel lymph node excision (SLNE) is probably the most im- portant diagnostic and potentially therapeutic procedure for ...
9
Cigarette smoking complements the prognostic value of baseline plasma Epstein-Barr virus deoxyribonucleic acid in patients with nasopharyngeal carcinoma undergoing intensity-modulated radiation therapy: a large-scale retrospective cohort study
... overall survival (OS); progression-free survival (PFS), distant metastasis- free survival (DMFS) and locoregional relapse-free survival (LRFS) were secondary ...
12
A new staging system for nasopharyngeal carcinoma based on intensity-modulated radiation therapy: results of a prospective multicentric clinical study
... overall survival (OS) curves of stages I, II, III and IVa were not significantly ...relapse-free survival (LRFS), distant metastasis-free survival (DMFS), and OS were all ...
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Original Article Prognostic significance of CD4/CD8 ratio in patients with breast cancer
... and survival rates were analyzed by the Kaplan-Meier method, log-rank test and multivariate Cox proportional hazards ...distant metastasis-free survival (DMFS, ...progression-free ...
7
Clinicopathologic characteristics and clinical outcomes of pure type and mixed type of tubular carcinoma of the breast: a single-institution cohort study
... cancer-specific survival (BCSS) was calculated from the date of operation, with death from breast cancer or death with active breast cancer being scored as an event; patients who died from any other causes or were ...
7
Robust genomic copy number predictor of pan cancer metastasis
... pan-cancer metastasis potential score (panMPS) based on observed ...predicts metastasis and metastasis-free survival in cohorts of patients with prostate cancer, triple negative breast ...
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<p>The Double-Edge Role of the Addition of Adjuvant Chemotherapy to Concurrent Chemoradiotherapy in the Treatment of Nasopharyngeal Carcinoma</p>
... achieved survival bene fi ts from ...node metastasis, or persis- tently detectable pEBV DNA after curative radiation therapy plus induction/concurrent ...of metastasis in low-risk ...overall ...
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FN14 and GRP94 expression are prognostic/predictive biomarkers of brain metastasis outcome that open up new therapeutic strategies
... the metastasis of basal breast tumors to the brain, whereas the absence of WNT/beta-catenin signaling allows luminal B-type tumors to metastasize to bone ...
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Overexpression of G6PD is associated with high risks of recurrent metastasis and poor progression free survival in primary breast carcinoma
... node metastasis, molecular subtypes, tumor staging and size, as well as pathological classification (all P > ...node metastasis (P = ...Multivariate survival analysis indicated that only G6PD ...
7
High infiltration of tumor-associated macrophages in triple-negative breast cancer is associated with a higher risk of distant metastasis
... In the current study, we evaluated the prognostic significance of TAMs in patients with TNBC. We found that patients with high TAM infiltration accounted for 35.9% of 287 TNBC cases. High TAM infiltration was associated ...
6
Infiltrating stromal immune cells in inflammatory breast cancer are associated with an improved outcome and increased PD L1 expression
... To examine this, we stained 5-μm FFPE slides with a validated PD-L1 (Clone SP142, Ventana) assay. While this assay is sensitive for immune cell staining, less tumour cell staining is seen when compared to others [21, ...
12
Proton beam therapy for cancer in the era of precision medicine
... relapse-free survival (RFS), DMFS, and LRF survival were ...intergroup survival were observed for patients with stage ...a survival benefit, especially in locally advanced ...
16
Original Article Overexpression of GRB2 is correlated with lymph node metastasis and poor prognosis in esophageal squamous cell carcinoma
... immunohistochemistry. Survival analysis demonstrated overexpression of GRB2 protein was significantly related to poor prognosis of ESCC patients (P = ...node metastasis revealed a shorter ...
9
Kinome and mRNA expression profiling of high-grade osteosarcoma cell lines implies Akt signaling as possible target for therapy
... correlated with survival, as was previously reported on the same dataset [9] by using the CIN25 signature [29]. IPA transcription factor analysis showed that MYC was the most significantly activated (z-score of ...
12
HMGA1 promotes breast cancer angiogenesis supporting the stability, nuclear localization and transcriptional activity of FOXM1
... conforming to the ITA guidelines (Dgl 26/2014) in ac- cordance with EU legislation (2010/63/UE); this protocol was approved by a committee of the Italian Health Minis- try (cod. 04086.N.15Y). In this study, the Tg ...
23
Efficacy and safety of primary surgery with postoperative radiotherapy in head and neck mucosal melanoma: a single-arm Phase II study
... limited survival. Since risk of distant metastasis is high for this disease, it is important for future clinical trials to use targeted agents or immune modulators to test potentially novel systemic ...
12
A case of long-term survival after surgical resection for solitary adrenal recurrence of esophageal squamous carcinoma
... Adrenal metastasis is generally identified on CT, PET, or MRI, during postoperative follow-up [10, ...adrenal metastasis is decided on an individual basis depending on the primary ...adrenal ...
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