Metoprolol Tartrate
DESIGN, FORMULATION AND IN VITRO EVALUATION OF SUSTAINED RELEASE PULSATILE CAPSULE OF METOPROLOL TARTRATE
... ABSTRACT: Pulsatile system is gaining a lot of interest as it increases patient compliance by means of providing time and site specific drug delivery system. This work will aim at the design of a sustained release ...
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EFFECT OF POLYMER RATIO AND EXCIPIENTS ON METOPROLOL TARTRATE RELEASE FROM CHITOSAN – SODIUM ALGINATE POLYMERIC IMPLANTS
... Scanning Electron Microscope (SEM): Prepared implants were analyzed for their surface morphology by scanning electron microscope. The implants were initially spread on a carbon tape glued to an aluminium stub and coated ...
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Design and in Vitro Evaluation of Transdermal Drug Delivery System of Metoprolol Tartrate
... Metoprolol tartrate is a beta adrenoreceptor blocking agent used in the treatment of cardiovascular ...using metoprolol tartarate orally may result in poor patient compliance because of low ...
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A NEW RP-HPLC METHOD DEVELOPMENT AND VALIDATION FOR SIMULTANEOUS ESTIMATION OF METOPROLOL TARTRATE AND TELMISARTAN IN PHARMACEUTICAL TABLET DOSAGE FORM
... of metoprolol tartrate and 8mg of telmisartan working standard was accurately weighed and transferred into a 10ml clean dry volumetric flask and add about 7ml of diluent and sonicate to dissolve it ...
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DEVELOPMENT AND EVALUATION OF ORALLY DISINTEGRATING TABLETS OF METOPROLOL TARTRATE BY DIRECT COMPRESSION METHOD USING DIFFERENT DILUENTS
... The formula was optimized for metoprolol tartrate orally disintigrating tablets to give fast relief and to increase the patient compliance. The micromeritic properties of all diluents were determined and ...
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Formulation and In-Vitro Evaluation of Metoprolol Tartrate Microspheres by using Natural Semisynthetic and Synthetic Polymers as Controlled Release Dosage Form
... Phase separation emulsion polymerization method was employed for the preparation of microspheres. Polymeric drug solution was prepared by adding 1gm of drug (Metoprolol tartrate) to 10ml of 10% solution of ...
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DESIGN, DEVELOPMENT AND IN-VITRO EVALUATION OF METOPROLOL TARTRATE FAST DISSOLVING TABLETSK. Ramesh Reddy*, V. Jayasankar Reddy, G. Saisri Harsha, K.AnilDOWNLOAD/VIEW
... Fast dissolving tablets of Metoprolol tartrate were prepared by direct compression. The term “direct compression” is defined as the process by which tablets are compressed directly from powder mixture of ...
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COMPARISON OF DIFFERENT SUPERDISINTEGRANTS IN DESIGNING OF FAST DISSOLVING TABLETS OF METOPROLOL TARTRATE
... Hence one of the C=O has undergone hydrogen bonding with the drug to give rise to adduct which is not a chemical reaction product. This hydrogen bond can undergo cleavage during metabolic process. The same drug ...
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FORMULATION AND CHARACTERIZATION OF MATRIX AND TRIPLE-LAYER MATRIX TABLETS FOR CONTROLLED DELIVERY OF METOPROLOL TARTRATE
... parameter based on zero-order model equation were mainly due to the drug release mechanism (Table 1). It was observed that the triple-layer matrix tablets swelled indicating that absorption of dissolution media and ...
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Analytical Method for the Simultaneous Estimation of Hydrochlorothiazide and Metoprolol Tartrate using RP HPLC
... powder, and weighed quantity of powder equal to half of the average weight, in each of the three 100 ml volumetric flasks. Then 50 ml of methanol was added in each of the volumetric flasks. The contents of the flask were ...
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In situ gel of metoprolol tartrate: Physicochemical characterization, In vitro diffusion and histological studies
... Metoprolol tartrate (MT), Carbopol 934P (CP), HPMC K4M and K15M were obtained from Polydrug labs,Thane, India, Ruger chemical Co. Inc., Irvington, NJ and Colorcon Asia Pvt. Ltd., Singapore, respectively. ...
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DESIGN AND IN VITRO CHARACTERIZATION OF GASTRO-RETENTIVE BILAYER FLOATING TABLET OF METOPROLOL TARTRATE
... (blockade effect) having half life 3-4hrs, which necessitates the administration twice a day in 25/50 mg. The polymers used are HPMC K4M, K15M, Ethyl cellulose and Xanthan gum, Guar gum, as gel forming agents and sodium ...
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Sublingual fast dissolving niosomal films for enhanced bioavailability and prolonged effect of metoprolol tartrate
... Abstract: The aim of the present work was to prepare and evaluate sublingual fast dissolving films containing metoprolol tartrate-loaded niosomes. Niosomes were utilized to allow for pro- longed release of ...
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Chemical stability indicating HPLC study of fixed dosage combination containing metoprolol tartrate and hydrochlorothiazide
... To a accurately weighted sample from the fixed-dose combination containing 0.02 g metoprolol tartrate and 0.005 g hydrochlorothiazide was added 50.0 ml buffer solution with pH = 2, 7.4 or 9 pH units. The ...
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DEVELOPMENT AND VALIDATION OF BIOANALYTICAL RP HPLC METHOD FOR THE ESTIMATION OF METOPROLOL TARTRATE IN RABBIT PLASMA AFTER TRANSDERMAL AND ORAL ADMINISTRATION: APPLICATION IN PHARMACOKINETIC STUDIES
... The Drug loaded monolithic matrix type transdermal patches were prepared by film casting technique on mercury substrate using different ratios of ERLPO:Methocel K15M, ERSPO:Methocel K15M, Acrylcoat S100:Methocel K15M and ...
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Development and Validation of Analytical Methods for the Simultaneous Estimation of Atorvastatin Calcium, Aspirin, Ramipril and Metoprolol Tartrate in Bulk and in Pharmaceutical Dosage form by UV Spectroscopy and Hptlc.
... and Metoprolol Tartrate in bulk and in combined dosage ...Ramipril, Metoprolol Tartrate and Aspirin were given in figures 1, 2, 3 and 4, ...and Metoprolol Tartrate were given in ...
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Development and In vitro evaluation of buccoadhesive tablets of metoprolol tartrate
... is the fractional release of the drug, t denotes the release time, k- constant incorporating structural and geometrical characteristics of the device and n- diffusional exponent that characterized the type of release ...
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DESIGN AND EVALUATION OF FAST DISSOLVING TABLET OF METOPROLOL TARTRATE
... METHODS: Metoprolol tartrate and Crosscarmellose sodium were obtained from Micro labs (Hosur, India) and Crosspovidone, Pregelatinized starch, and Mannitol were obtained as gift samples from Aurobindo labs ...
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Permeation studies of atenolol and metoprolol tartrate from three different polymer matrices for transdermal delivery
... develop the transdermal delivery of certain β 1 -blockers i.e. atenolol and metoprolol tartrate (both the drugs are incompletely absorbed from GIT and have half–lives of about 6-7 h, respectively). Hence, ...
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Original Article Therapeutic effect and prognostic life quality of renal denervation therapy and nifedipine combined with metoprolol tartrate in the treatment of resistant hypertension
... with metoprolol tartrate could affect the therapeu- tic effect, safety and prognosis of ...with metoprolol tartrate was better than that of RDN and nife- dipine ...
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