MHC class II
Designing of interferon-gamma inducing MHC class-II binders
... Comment: 2) inclusion/exclusion criteria. As an exer- cise, I went to the IEDB and searched for all MHC class II binders that do not elicit an interferon-gamma response. I then randomly chose ...
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Tolerance to solid organ transplants through transfer of MHC class II genes
... Animals and protocols used in this study. Massachusetts General Hospital Miniature Swine (3–5 months old) received either allogeneic or syngeneic MHC class II cDNA through transduction of autologous ...
8
Cloning, Expression, and Functional Analyses of MHC Class II A in Ayu, Plecoglossus altivelis
... Meseguer, 2006), large yellow croaker (Larimichthys crocea) (Yu, Ao, & Chen, 2010), Miiuy croaker (Miichthys miiuy) (Xu, Sun, Shi, Cheng, & Wang, 2011), Nile tilapia (Oreochromis niloticus) (Pang et al., 2013), ...
10
The interaction of HLA-DM with conventional MHC class II molecules
... f MHC class II m ...the class II m o lecu les in \i~l~ anim als are re ta in e d in the E R w here they associate with molecules o f the “ER quality control m achinery” like ...HC ...
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Association of CD99 short and long forms with MHC class I, MHC class II and tetraspanin CD81 and recruitment into immunological synapses
... including MHC and tetraspanin CD81, have been shown to translocate into the IS dur- ing T cell activation ...with MHC class II of APCs has been observed in which they function as cell surface ...
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Tumor-specific CD4 T cells eradicate myeloma cells genetically deficient in MHC class II display
... constitutive MHC II expression, MOPC315 cells may start to express MHC class II under certain in vivo conditions, as observed for the B16 melanoma [1, ...express MHC class ...
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The systems biology of MHC class II antigen presentation
... and MHC class II vesicles and the Golgi were detected as primary objects and then assigned to a cell containing this object (their ...for MHC class II, three for early endosome ...
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Sex-dependent treatment of chronic EAE with partial MHC class II constructs
... The design, production, and characterization of the partial MHC class II constructs have been described elsewhere [15, 18]. In the DR*1501-Tg mice experi- ments, RTL342M, which contains the human ...
11
Footprints of antigen processing boost MHC class II natural ligand predictions
... above, MHC-II motif characterization and rational identification of MHC-II ligands and epitopes is a highly challenging and costly ...Because MHC-II is a crucial player in the ...
15
A Novel Predictive Technique for the MHC Class II Peptide-Binding Interaction
... the MHC Class II peptide–binding ...the MHC Class II allele DR1-0101 bound to an endogenous peptide (PDB code:1AQD) (12) has been elucidated by X-ray diffraction at a resolution ...
6
Evolution of MHC Class II Eβ Diversity Within the Genus Peromyscus
... the MHC has been slowed by an inability to assess the relative roles of mutation ...of class II ...the MHC. We investigated the evolution of MHC class II E sequence ...
10
Susceptibility of amphibians to chytridiomycosis is associated with MHC class II conformation
... the MHC class II in amphibians illustrating peptide-binding ...the MHC peptide-binding ...all MHC-II b1 included in the study is available in the electronic supplementary ...
9
Presentation of intracellular antigen with MHC class II molecules
... investigated class II presentation of influenza haem agglutinin (HA) transport m utants in B ...ith class II in a chloroquine-sensitive m ...ith MHC class II, b u t in a ...
235
IFN-γ-induced increase in the mobility of MHC class II compartments in astrocytes depends on intermediate filaments
... of MHC II molecules in astrocytes is thought to be controlled by neurons, since IFN-γ induces MHC class II expression only in slice culture zones containing degenerated neu- rons, in ...
13
Molecular basis for the control of motor-based transport of MHC class II compartments
... for MHC II antigen presentation? Eliminating MHC II, cathepsin S or HLA-DM still shows LEs labeling for the conventional markers, indicating that MHC II-related proteins are not ...
144
MHC class II-restricted T cell responses to flaviviruses
... Further, when the class II antigens from resting and activated B cells were incorporated in artificial planar membranes they showed a similar capacit'y to present ovalbumin peptides to s[r] ...
243
Blocking MHC class II on human endothelium mitigates acute rejection
... of class II MHC molecules on allogeneic EC limit CTL-mediated rejection in vivo? This is the likeliest interpreta- tion of our finding that blockade of HLA-DR recognition by antibody limited ...
17
Inconsistent MHC class II association in Beagles experimentally infected with Leishmania infantum
... Parasite load in the bone marrow for representative dogs in study B. Leishmania DNA 653[r] ...
31
Co-culture of primary human tumor hepatocytes from patients with hepatocellular carcinoma with autologous peripheral blood mononuclear cells: study of their in vitro immunological interactions
... of MHC II on their surface compared to non-HCC hepatocytes, expression that is further enhanced upon co-culture with autologous PBMCs at all time ...Increased MHC-II expression was also ...
12
Norovirus immunobiology and vaccine design
... To determine the role of T cells in clearance of acute MNV infection, we inoculated wild type, MHC Class II-/-, and MHC Class I x β 2-m −/− mice orally with MNV1.CW3 and measured vir[r] ...
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