Miconazole Nitrate
![(+) 1 {(2S) 2 (2,4 Dichlorophenyl) 2 [(2,4 dichlorophenyl)methoxy]ethyl} 1H imidazole mononitrate [(+) (S) miconazole nitrate]](data:image/gif;base64,R0lGODlhAQABAIAAAP///wAAACH5BAEAAAAALAAAAAABAAEAAAICRAEAOw==)
(+) 1 {(2S) 2 (2,4 Dichlorophenyl) 2 [(2,4 dichlorophenyl)methoxy]ethyl} 1H imidazole mononitrate [(+) (S) miconazole nitrate]
... nitrate, is a component of racemic miconazole nitrate, a broad spectrum antimycotic agent with antibacterial activity. It crystallizes with two protonated molecules in the asymmetric unit, both with ...
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QUANTITATIVE ANALYSIS OF MICONAZOLE NITRATE IN BINARY MIXTURE WITH BETAMETHASONE VALERATE IN BULK POWDER AND CREAM FORMULATION BY VARIOUS SPECTROPHOTOMETRIC TECHNIQUES
... of miconazole nitrate and betamethasone ...of miconazole nitrate as shown in figure (4), which is equivalent to recorded concentration of miconazole nitrate in the mixture (C ...
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Simultaneous analysis of mometasone furoate, miconazole nitrate, and nadifloxacin in cream formulation by HPTLC
... 8(4-hydroxy-1-piperidyl)-5-methyl-1-oxo-1H,5H-benzo-(ij)- quinolizine-2-carboxylic acid (Fig. 1c) is a fluoroquinolone showing antibacterial activity which is a second-generation broad spectrum category, and is used to ...
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DEVELOPMENT AND VALIDATION OF SPECTROPHOTOMETRIC METHODS FOR THE SIMULTANEOUS ESTIMATION OF MICONAZOLE NITRATE AND METRONIDAZOLE IN BULK POWDER FORM
... 10.0 mg of drug was weighed accurately and dissolved in 1.0 ml of methanol (UV grade) and volume was made with phosphate buffer in 10.0 ml of volumetric flask. 1.0 ml of this solution was pipette and diluted to 10.0 ml ...
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Derivative, derivative of the ratio spectrophotometric and stability indicating RP HPLC methods for the determination of mometasone furoate and miconazole nitrate in cream
... and miconazole nitrate were determined using ∆λ= 4 at ...with miconazole nitrate on reversed phase C18 column, ...and miconazole nitrate was detected at 230 nm at ambient ...and ...
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“TO DEVELOP AND VALIDATE ASSAY METHODS FOR THE ESTIMATION OF HALOBETASOL PROPIONATE AND MICONAZOLE NITRATE IN MARKETED FORMULATION”
... The present study was attempted for development and validation of methods for the estimation of Halobetasol propionate and Miconazole nitrate in marketed formulation. This study is aimed to established a ...
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Formulation and Development of Antifungal Nail Lacquer Containing Miconazole Nitrate Use in Treatment of Onychomycosis
... Miconazole nitrate 100mg pure drug was right weighed and transfer into a 100ml volumetric flask of medium. And the volume was made up to 100ml with PBS of pH 7.4, to come into ownership standard stock ...
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Design and characterization of miconazole nitrate loaded nanosponges containing vaginal gels
... ratio. Miconazole nitrate was incorporated into nanosponges by solvent evaporation method by dissolving the drug in ...of Miconazole nitrate using polymers like HPMC, NaCMC, ...
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METHOD DEVELOPMENT AND VALIDATION FOR SIMULTANEOUS ESTIMATION OF CLOTRIMAZOLE, MICONAZOLE NITRATE, AND TINIDAZOLE BY REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY METHOD IN TABLETS:
... clotrimazole, miconazole nitrate, and tinidazole (25 mg of clotrimazole and miconazole nitrate and 50 mg of tinidazole) that were weighed accurately and separately transferred into 25 ml ...
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SIMULTANEOUS DETERMINATION OF MICONAZOLE NITRATE AND HYDROCORTISONE IN BULK POWDER AND INTOPICAL CREAM USING FOUR CHEMOMETRIC METHODS
... 7. Quantification, accuracy and precision The characteristic parameters and the linear regression equations together with correlation coefficients, slope, intercept, R.S.D. of slope and intercept, repeatability (within ...
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FORMULATION AND EVALUATION OF MICONAZOLE NITRATE LOADED NANOSPONGES FOR VAGINAL DRUG DELIVERYP.Suresh Kumar *, N.Hematheerthani J.Vijaya Ratna and V.SaikishorDOWNLOAD/VIEW
... The aim of this work is to enhance the solubility of Miconazole nitrate and to control the drug release for a prolonged period. β-Cyclodextrin based nanosponges were prepared by cross-linking β-Cyclodextrin ...
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FORMULATION AND EVALUATION OF MICONAZOLE NITRATE AS A CUBOSOMAL TOPICAL GEL
... of Miconazole nitrate as cubosomal topical gel to improve the efficacy & bioavailability of Miconazole ...phase. Miconazole nitrate is an antifungal drug with 20% oral ...the ...
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FORMULATION AND IN-VITRO EVALUATION OF ORAL HYDROGEL CONTAINING MICONAZOLE NITRATE
... The selected gel formulation that showed the best release was subjected to this study. The formulation was tested for its in-vitro release was miconazole nitrate to the agar and its antifungal activity ...
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SOLUBILITY ENHANCEMENT OF MICONAZOLE NITRATE FOR FORMULATION AND EVALUATION OF MUCOADHESIVE GEL
... CURRENT & FUTURE DEVELOPMENTS Currently only 8% of new drug candidates have both high solubility and permeability. Because of solubility problems of many drugs their bioavailability gets affected and hence solubility ...
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TRANSFEROSOMES: A NOVEL APPROACH TO DELIVER OF MICONAZOLE NITRATE FOR TOPICAL PREPRATION
... in miconazole nitrate + lipid , miconazole nitrate + cholesterol , miconazole nitrate + carbopol 940 and miconazole nitrate + methanol were similar as recorded in ...
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DESIGN, DEVELOPMENT AND EVALUATION OF MICONAZOLE NITRATE TOPICAL GEL FOR FUNGAL INFECTIONS
... idomycosis, Crypto coccosis, Para coccidio idomycosis, and infections due to Pseudeli escheria. The drug undergoes substantial first pass metabolism and only half the amount of it is bioavailable systemically. To avoid ...
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Fabrication and characterization of chitosan carbopol 71G polyelectrolyte complex based mucoadhesive pellets of miconazole nitrate for vaginal candidiasis
... Various approaches have been used in the past to overcome the problems associated with the delivery of antifungal drugs, for effective treatment of vaginal candidiasis. In the present investigation, mucoadhesive ...
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FORMULATION AND EVALUATION OF ETHOSOMAL GEL OF MICONAZOLE NITRATE FOR FUNGAL INFECTION BY COLD METHOD
... that miconazole was freely soluble in methanol, ethanol and ...pure miconazole were given in fig ...of miconazole were determined by running the spectrum of drug solution in double beam ultraviolet ...
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FORMULATION AND EVALUATION OF BIOADHESIVE MATRIX TABLET OF AN ANTIFUNGAL DRUG
... of Miconazole Nitrate were formulated by using polymers such as HPMC and ...of miconazole nitrate from bioadhesive matrix tablet and it was found that, they followed non-fickian diffusion ...
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Formulation and Evaluation of a Medicated Nail Lacquer for the Treatment of Onychomycosis
... Onychomycosis (tineaunguium) is a fungal infection of the nail bed or nail plate that accounts for approximately 50% of all nail diseases and is the most common disorder in adults. Onychomycosis though rarely life ...
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