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Microglial Cells

Hyperglycaemia and apoptosis of microglial cells in human septic shock

Hyperglycaemia and apoptosis of microglial cells in human septic shock

... induce microglial apoptosis by enhancing for- mation of oxidative free radicals ...and microglial apoptosis suggest that they are interdependent phenom- ...and microglial cells ...induces ...

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Inhibition of CD200R1 expression by C/EBP beta in reactive microglial cells

Inhibition of CD200R1 expression by C/EBP beta in reactive microglial cells

... of microglial activity by ...glial cells in a quiescent/surveying phenotype in which the pro-inflammatory response is inhibited, and that microglial cells show increased reactivity when the ...

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Interleukin-1β-induced inflammatory signaling in C20 human microglial cells

Interleukin-1β-induced inflammatory signaling in C20 human microglial cells

... Figure 3. Interleukin-1β (IL-1β)-induced inhibitory kappa B alpha (IκBα) activation in C20 human microglial cells. C20 cells were exposed to media alone (unstimulated; US) or media containing IL-1β ...

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GLP-1 secretion by microglial cells and decreased CNS expression in obesity

GLP-1 secretion by microglial cells and decreased CNS expression in obesity

... immune cells of the CNS (microglia) as a possible source of the proglucagon mRNA expression observed in these areas of the ...glial cells and detected GLP-1- positive microglia cells (Figure ...

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Oxytocin inhibits lipopolysaccharide-induced inflammation in microglial cells and attenuates microglial activation in lipopolysaccharide-treated mice

Oxytocin inhibits lipopolysaccharide-induced inflammation in microglial cells and attenuates microglial activation in lipopolysaccharide-treated mice

... Microglia are able to undergo a variety of morpho- logical and functional changes in response to various im- munological stimuli. Quiescent microglia exhibit a ramified cell morphology with relatively small size and ...

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Magnolia polyphenols attenuate oxidative and inflammatory responses in neurons and microglial cells

Magnolia polyphenols attenuate oxidative and inflammatory responses in neurons and microglial cells

... in microglial cells, the mechanisms for ROS production have not been clearly elucidated ...with microglial cells, ROS production induced by LPS and IFNγ was not observed before 4 h (Figure ...

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Remodeling of lipid bodies by docosahexaenoic acid in activated microglial cells

Remodeling of lipid bodies by docosahexaenoic acid in activated microglial cells

... hepatic cells [65] and resol- vin D1 and E1 to decrease LPS-induced TNFα, IL-6, and IL-1β gene expressions in cultured microglial ...N9 microglial cells could exacerbate mitochondrial ...

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Effects of chronic low dose rotenone treatment on human microglial cells

Effects of chronic low dose rotenone treatment on human microglial cells

... producing cells themselves, these do not appear to cause substantial damage to microglial cells [33], suggesting that microglial cells are well equipped with a strong antioxidative ...

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α 1-antitrypsin modulates microglial-mediated neuroinflammation and protects microglial cells from amyloid-β-induced toxicity

α 1-antitrypsin modulates microglial-mediated neuroinflammation and protects microglial cells from amyloid-β-induced toxicity

... activates microglial cells via differ- ent receptors expressed on the cell surface, such as toll-like receptors (TLR) ...activation, microglial cells express and secrete pro-inflammatory ...

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Neuropeptide Y inhibits interleukin-1β-induced phagocytosis by microglial cells

Neuropeptide Y inhibits interleukin-1β-induced phagocytosis by microglial cells

... of microglial phagocytic activity induced by lipopolysac- charide (LPS) to evaluate the role of NPY on Fc receptor- mediated ...phagocytosis. Microglial cells are constantly prowling the brain ...

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Anti-inflammatory effects of spermidine in lipopolysaccharide-stimulated BV2 microglial cells

Anti-inflammatory effects of spermidine in lipopolysaccharide-stimulated BV2 microglial cells

... of microglial cells leads to an increased production of pro- inflammatory mediators and ...BV2 microglial cells resulted in signifi- cant inhibition of the production of the LPS-induced ...

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LPS-induced TLR4 neuroinflammatory signaling in CHME-5 microglial cells

LPS-induced TLR4 neuroinflammatory signaling in CHME-5 microglial cells

... of microglial cell lines is limited, thus, it is important to maximize our understanding of those tools that are ...CHME-5 cells by characterizing TLR4 neuroinflammatory signaling, which aligned with ...

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Microglial cells in astroglial cultures: a cautionary note

Microglial cells in astroglial cultures: a cautionary note

... for microglial cells in vitro later became ...why microglial cells in astro- glial cultures have sometimes been ignored is related to the image obtained after glial fibrillary acidic protein ...

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In Vitro Activation of Feline Immunodeficiency Virus in Ramified Microglial Cells from Asymptomatically Infected Cats

In Vitro Activation of Feline Immunodeficiency Virus in Ramified Microglial Cells from Asymptomatically Infected Cats

... resident cells, which certainly include microglia (3, ...in microglial cells and probably also in latently infected astro- cytes, as has been suggested by Messam and Major ...antibody-secreting ...

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Cudratricusxanthone L Suppresses Lipopolysaccharide-induced Activation of BV2 and Primary Rat Microglial Cells by Inhibiting JNK, p38 MAPK, and NF-κB Signaling

Cudratricusxanthone L Suppresses Lipopolysaccharide-induced Activation of BV2 and Primary Rat Microglial Cells by Inhibiting JNK, p38 MAPK, and NF-κB Signaling

... microglial cells. NF-κB translocation was blocked in BV2 microglial cells exposed to cudratricusxanthone L (1) (Figure 5B and ...BV2 microglial cells challenged with ...

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Toll-like receptor stimulation increases phagocytosis of Cryptococcus neoformans by microglial cells

Toll-like receptor stimulation increases phagocytosis of Cryptococcus neoformans by microglial cells

... unstimulated microglial cells was included in all ...from microglial cells stimulated for 24 h were collected and kept frozen at −20°C until ...

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Possible role of microparticles in neuroimmune signaling of microglial cells

Possible role of microparticles in neuroimmune signaling of microglial cells

... THP-1 cells to MPs (10 μg protein/mL) isolated from THP-1 cells that had been stimulated with IFN- γ alone or in combination with LPS for 48 ...THP-1 cells possess the ability to induce monocytic ...

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Pathogenesis and Immune Response in Tuberculous Meningitis

Pathogenesis and Immune Response in Tuberculous Meningitis

... macrophages, microglial cells, astrocytes, and endothelial ...endothelial cells in vitro after the administration of these proinflammatory cytokines ...and microglial cells can also ...

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Neuromelanin activates proinflammatory microglia through a caspase-8-dependent mechanism

Neuromelanin activates proinflammatory microglia through a caspase-8-dependent mechanism

... microglial cells. Analysis of IETDase and DEVDase activities in BV2 cells demonstrated a modest yet signifi- cant increases of caspase-8 and caspase-3 activities in response to neuromelanin ...of ...

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Original Article Huperzine A protects neural stem cells against Aβ-induced apoptosis in a neural stem cells and microglia co-culture system

Original Article Huperzine A protects neural stem cells against Aβ-induced apoptosis in a neural stem cells and microglia co-culture system

... cause microglial cells to accumulate around Aβ plaques in AD ...patients. Microglial cells, stimulated by Aβ, release inflammatory factors including MIP-ld, forming a vicious circle (ieroglia ...

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