MicroRNA-133b
Original Article Down-regulation of microRNA-126 and microRNA-133b acts as novel predictor biomarkers in progression and metastasis of non small cell lung cancer
... of microRNA-126 (miR-126) and microRNA-133b (miR-133b) and also their association with clinicopatho- logical features in patients with non small cell lung cancer ...
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Original Article MicroRNA-133b inhibits proliferation and invasion of ovarian cancer cells through Akt and Erk1/2 inactivation by targeting epidermal growth factor receptor
... Abstract: Aberrant expression of microRNA-133b (miR-133b) has been frequently reported in some cancers exclud- ing ovarian cancer (OC). The role and its molecular mechanism of miR-133b in OC ...
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Protein phosphatase 2A-B55δ enhances chemotherapy sensitivity of human hepatocellular carcinoma under the regulation of microRNA-133b
... miR-133b: microRNA-133b; miRNAs: microRNAs; MTT: 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide; OD: optical density; oncomiR: oncogenic miRNA; pBabe: plasmid pBabe-puro; p-CDK1: ...
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MicroRNA-133b targets glutathione S-transferase π expression to increase ovarian cancer cell sensitivity to chemotherapy drugs
... miR- 133b, 5 ′ -UUU GGU CCC CUU CAA CCA GCU A-3 ′ ; miR-C, 5 ′ -UUC UCC GAA CGU GUC ACG UTT-3 ′ ; anti- miR-133b, 5 ′ -UAG CUG GUU GAA GGG GAC CAA A-3 ′ ; and anti-C, 5 ′ -CAG UAC UUU UGU GUA GUA CAA-3 ′ ...
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Original Article Down-regulation of microRNA-133b protects human esophageal squamous cells Het-1A from hydrochloric acid-induced apoptosis
... An increasing number of literatures have reported that miR-133b serves as a pivotal reg- ulator in multiple biological progresses, espe- cially in cell proliferation and apoptosis. Chen et al. found that ...
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<p>Downregulation Of microRNA-133b And Its Clinical Value In Non-Small Cell Lung Cancer</p>
... with differentially expressed genes in NSCLC such as P53 signaling pathway and ECM-receptor interaction. In addi- tion, KEGG pathway analysis of the most frequently altered neighbor genes showed enrichment of the ...
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Mesenchymal stem cell-derived exosomal microRNA-133b suppresses glioma progression via Wnt/β-catenin signaling pathway by targeting EZH2
... In conclusion, our finding evidenced that MSC-derived exosomes transferring miR-133b into glioma cells could potentially inhibit EZH2 expression via blocking the Wnt/ β -catenin signaling pathway, thereby ...
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MicroRNA-133b/EGFR axis regulates esophageal squamous cell carcinoma metastases by suppressing anoikis resistance and anchorage-independent growth
... Cancer cells detachment from ECM and the subsequent proliferation under anchorage-independent growth con- dition are considered as an early step of cancer metasta- sis [34]. Under normal condition, the detached normal ...
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The role of microRNA-133b and its target gene FSCN1 in gastric cancer
... miR-133b can inhibit GC cell migration and invasion We further assessed the effects of miR-133b on cell migra- tion and invasion, which were the important determinants of malignant progression and ...
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Original Article MicroRNA-133b negatively regulates the proliferation and osteogenic differentiation of bone marrow mesenchymal stem cells
... miR- 133b downreguation/upregulation on proliferation and osteogenic differentiation were evaluated by MTT, expres- sion levels of osteogenic differentiation markers and Alizarin red S ...
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microRNA-1/133a and microRNA-206/133b clusters: Dysregulation and functional roles in human cancers
... that microRNA-1 (miR-1), microRNA-133a (miR-133a), microRNA- 133b (miR-133b) and microRNA-206 (miR-206) are frequently downregulated in various types of ...
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MicroRNA-374a, -4680, and -133b suppress cell proliferation through the regulation of genes associated with human cleft palate in cultured human palate cells
... Lastly, we assessed the predicted miR-133b down- stream target genes. We found that expression of FGFR1, GCH1, PAX7, SMC2, and SUMO1 was signifi- cantly downregulated in cultured cells treated with miR- ...
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Network vulnerability-based and knowledge-guided identification of microRNA biomarkers indicating platinum resistance in high-grade serous ovarian cancer
... Outlier MicroRNA Analysis (POMA) and MicroRNA Bio- marker Discovery (MicroRNA-BD), were developed to identify miRNA biomarkers for predicting cancer ini- tiation and metastasis with high performance ...
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The Intestinal Microbiota Interferes with the microRNA Response upon Oral Listeria Infection
... ABSTRACT The intestinal tract is the largest reservoir of microbes in the human body. The intestinal microbiota is thought to be able to modulate alterations of the gut induced by enteropathogens, thereby maintaining ...
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MicroRNA Deregulations in Head and Neck Squamous Cell Carcinomas
... existing microRNA profiling studies on HNSCC include cases from multiple anatomical ...specific microRNA signatures for various HNSCC subtypes should be identified, which will lead to substantial ...
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MicroRNA 889 Inhibits Autophagy To Maintain Mycobacterial Survival in Patients with Latent Tuberculosis Infection by Targeting TWEAK
... individual biologic (10 g/ml) was added. At 24 h posttreatment, miR-889 expression was measured using QRT-PCR. ADA, adali- mumab; ETA, etanercept; RTX, rituximab. (J to M) MicroRNA-889 inhibits ...
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Characterization and potential role of microRNA in the Chinese dominant malaria mosquito Anopheles sinensis (Diptera: Culicidae) throughout four different life stages
... Results: In total, 164 miRNAs were obtained out of 107.46 million raw sequencing reads. 99 of them identified as known miRNAs, and the remaining 65 miRNAs were considered as novel. By analyzing the read counts of miRNAs ...
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Retinoic acid induces HL-60 cell differentiation via the upregulation of miR-663
... granulocytic differentiation. Both miR-107 and miR-223 are postulated to downregulate their target gene NFI-A, and mediate a regulatory loop during cell differentiation [22]. This data suggests miRNAs can function as ...
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Targeting myomiRs by tocotrienol-rich fraction to promote myoblast differentiation
... MicroRNAs (miRNAs) have gained tremendous atten- tion and provide a new avenue for understanding the regulatory mechanism of skeletal muscle development. miRNAs are evolutionary conserved small RNAs that have been ...
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Prediction and Analysis of SARS-CoV-2-Targeting microRNA in Human Lung Epithelium
... that microRNA can mediate an intracellular defence mechanism against some RNA ...identify microRNA with predicted binding sites in the SARS-CoV- 2 genome, compare these to their microRNA expression ...
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