MicroRNA-26a
<p>MicroRNA-26a-5p inhibits proliferation, invasion and metastasis by repressing the expression of Wnt5a in papillary thyroid carcinoma</p>
... 21 MicroRNA-26a-5p (miR- 26a-5p), a tumor-associated miR, has been found to be implicated in the development of various cancers by reg- ulating tumor cell proliferation, invasion, migration and ...
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MicroRNA-26a promotes anoikis in human hepatocellular carcinoma cells by targeting alpha5 integrin
... that microRNA-26a (miR-26a) is an important tumor suppressor that inhibits the proliferation and invasion of HCC cells by targeting multiple oncogenic ...
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Original Article MicroRNA-26a promotes epithelial mesenchymal transition in pleural mesothelial cells
... that microRNA-26a (miR-26a) play a key role in the process of ...miR- 26a in PMC Epithelial Mesenchymal Transition ...miR- 26a and smad-2 ...
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<p>microRNA-26a Directly Targeting MMP14 and MMP16 Inhibits the Cancer Cell Proliferation, Migration and Invasion in Cutaneous Squamous Cell Carcinoma</p>
... that microRNA- 26a-5p (miR-26a) can promote autophagy of myocardial cells to combat the injury of myocardial infarction and has an important role in myocardial ...
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MicroRNA-26a suppresses epithelial-mesenchymal transition in human hepatocellular carcinoma by repressing enhancer of zeste homolog 2
... Liver cancer (mostly hepatocellular carcinoma [HCC]) is the sixth most prevalent cancer worldwide [1], and it is the second most frequent cause of cancer-related death in men and the sixth most frequent in women [2]. ...
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Original Article Regulation of diabetes-induced inflammation in macrophages by microRNA-26a-5p
... Abstract: Background: Diabetes is one of the most common metabolic disorders and most important health threats. Recently, the risk of inflammation related to diabetes has been recognized. microRNAs (miRNAs) are ...
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microRNA-26a suppresses recruitment of macrophages by down-regulating macrophage colony-stimulating factor expression through the PI3K/Akt pathway in hepatocellular carcinoma
... Results: Ectopic expression of miR-26a reduced expression of M-CSF. The conditioned medium (CM) from HepG2 cells that overexpressed miR-26a reduced the migration ability of THP-1 cells stimulated by phorbol ...
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microRNA-26a induces a mitochondrial apoptosis mediated by p53 through targeting to inhibit Mcl1 in human hepatocellular carcinoma
... the luciferase activity of miR-26a-1 containing a wild- type promoter sequence but did not increase the activity of miR-26a-1 with a mutant promoter region (P,0.01, Figure 5A). Moreover, overexpression of ...
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<p>microRNA-26a-5p Promotes Proliferation and Migration of Osteosarcoma Cells by Targeting <em>HOXA5</em> in vitro and in vivo</p>
... To investigate the molecular function of miR-26a-5p in U2OS, we transfected U2OS with miRNA mimic and inhi- bitor, respectively. Twenty-four hours after transfection, the mRNA levels of miR-26a-5p and ...
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MicroRNA 26a negatively regulates toll like receptor 3 expression of rat macrophages and ameliorates pristane induced arthritis in rats
... To observe whether miR-26a overexpression in vivo can influenze arthritis severity, PIA rats were treated with miR-26a mimic, NC mimics and saline four times until rats were sacrificed (Figure 6A). The ...
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Original Article MicroRNA-26a inhibits proliferation by targeting high mobility group AT-hook 1 in breast cancer
... miR-26a in the 3’-UTR of HMGA1 mRNA. To confirm that miR-26a can bind to the predicted site, we performed a luciferase reporter assay in the 293T cell line. Figure 4A shows that the luciferase activity ...
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RETRACTED ARTICLE: Down-regulation of microRNA-26a and up-regulation of microRNA-27a contributes to aggressive progression of human osteosarcoma
... The expression level of miRNAsin the osteosarcoma and corresponding non-cancer tissues was evaluated by qRT- PCR assay. The total RNA was purified from samples noncancerous bone tissue using TRI zolaccording to the ...
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MicroRNA 26a regulates insulin sensitivity and metabolism of glucose and lipids
... miR-26a increases insulin-stimulated AKT activation. As shown above, both Hprt- and Alb-Mir26a Tg mice are resistant to obesity-induced insulin resistance. To further explore this, we directly assessed the effect ...
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Extracellular microRNA-21 and microRNA-26a increase in body fluids from rats with antigen induced pulmonary inflammation and children with recurrent wheezing
... Results: The increase of plasma miR-21 and miR-26a was screened out from 11 candidate miRNAs and validated in wheezing children. The level of expression for both miRNAs were comparable in different age and gender. ...
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MicroRNA-26a-mediated regulation of interleukin-2 expression in transformed avian lymphocyte lines
... Background: Micro(mi)RNAs are a class of small non-coding RNAs that play critical roles in the induction of various cancers, including lymphomas induced by oncogenic viruses. While some of the miRNAs are oncogenic, ...
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Glioma stem cells-derived exosomal miR-26a promotes angiogenesis of microvessel endothelial cells in glioma
... miR-26a, microRNA-26a; NC, negative control; PTEN, phosphatase and tensin homolog deleted on chromosome ten; Akt, protein kinase B; VEGF, vascular endothelial growth factor; GSCs, glioma stem cells; ...
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MiR-26a and miR-144 inhibit proliferation and metastasis of esophageal squamous cell cancer by inhibiting cyclooxygenase-2
... We searched the databases TargetScan, PicTar, miRwalk, DIANAmT, microRNA, Microcosm Targets and MicroRanda for miRNAs that might bind to the 3’ -UTR of COX-2. Four candidates including miR- 101, miR143, ...
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Proposal for a Council Directive amending Directive 85/811/EEC on the coordination of laws, regulations and administrative provisions relating to undertakings for collective investment in transferable securities (UCITS). COM (93) 37 final, 9 February 1993
... After Article 26 the following new Article 26a shall be added: "Article 26a Notwithstanding Article 242, Article 243 first subparagraph and Art.lcle 252 third Indent a UCITS hereinafter [r] ...
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Original Article Down-regulation of microRNA-126 and microRNA-133b acts as novel predictor biomarkers in progression and metastasis of non small cell lung cancer
... [8] Zhang LY, Ho-Fun Lee V, Wong AM, Kwong DL, Zhu YH, Dong SS, Kong KL, Chen J, Tsao SW, Guan XY, Fu L. MicroRNA-144 promotes cell proliferation, migration and invasion in naso- pharyngeal carcinoma through ...
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Differences in microRNA expression between melanoma and healthy adjacent skin
... To confirm the microarray results, total RNA previously isolated from melanoma and healthy adjacent skin samples wasused to estimate the expression levels of miR-363-3p and miR-3591. These microRNAs were ...
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