Migration and invasion
Original Article MiR-23b inhibits cell migration and invasion through targeting PDE7A in colon cancer cells
... the invasion and metas- tasis of colon cancer by regulating PDE7A ...cell invasion and migration was determined by Transwell ...and invasion abilities of SW620 cells or SW480 ...the ...
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The inhibition role of miR-22 in hepatocellular carcinoma cell migration and invasion via targeting CD147
... RT‑PCR. Invasion assay, MTT proliferation assay and wound‑healing assay were performed to test the invasion and proliferation of HCC cell after overexpression of ...proliferation, migration and ...
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Original Article NUAK1 knockdown suppresses prostate cancer cell epithelial-mesenchymal transition, migration, and invasion through microRNA-30b-5p
... cell migration and ...EMT, migration and ...EMT, migration, and invasion in prostate cancer cells and introduction of NUAK1 abated the inhibitory ...EMT, migration and invasion ...
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<p>HNF1A-AS1 Regulates Cell Migration, Invasion and Glycolysis via Modulating miR-124/MYO6 in Colorectal Cancer Cells</p>
... Materials and Methods: The expression of HNF1A-AS1, microRNA-124 (miR-124) and Myosins of class VI (MYO6) was detected using reverse transcription-quantitative polymer- ase chain reaction (RT-qPCR). The analysis of ...
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Roles of CXCL5 on migration and invasion of liver cancer cells
... proliferation, migration, and invasion [28] and to assist cancer cells in evading stress-induced apoptosis ...LCC migration and invasion when the concentration of CXCL5 in the environment ...
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The role of SH3GL3 in myeloma cell migration/invasion, stemness and chemo-resistance
... cell migration and invasion, we first overexpressed SH3GL3 in a myeloma cell ...cell migration (Figure ...enhanced migration and invasion of myeloma ...
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<p>lncRNA DSCAM-AS1 downregulates miR-216b to promote the migration and invasion of colorectal adenocarcinoma cells</p>
... cell migration and invasion. miR-216b inhibited cancer cell migration and invasion and signi fi cantly reduced the effects of DSCAM-AS1 ...
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RND3 promotes Snail 1 protein degradation and inhibits glioblastoma cell migration and invasion
... However, emerging evidence has suggested that other regulatory signaling pathways are also involved in RND3-mediated regulations. In esophageal squamous cells, forced expression of RND3 suppresses cell migration ...
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Migration and invasion enhancer 1 (MIEN1) is overexpressed in breast cancer and is a potential new therapeutic molecular target.
... and invasion enhancer 1 (MIEN1), previously known as C35 or C17orf37, is a transforming oncogene that is involved in various types of cancers, and is located within the smallest region of amplification of the HER2 ...
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ECM1 promotes migration and invasion of hepatocellular carcinoma by inducing epithelial mesenchymal transition
... cell migration and invasion, the exact mechanisms by which ECM1 promoted tumor progression remained ...and migration and invasion are the main factors of recurrence of ...the migration ...
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Inhibition of invasion and migration of prostate cancer cells by miRNA-509-5p via targeting MDM2.
... MicroRNA (miRNA), a type of non-coding single stranded RNA with 19~25 nucleotide acids, is widely distributed in eukaryotes and regulates the occurrence and progression of malignant tumors via negative regulation of gene ...
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<p>Long Non-Coding RNA PVT1 Regulates BAMBI To Promote Tumor Progression In Non-Small Cell Lung Cancer By Sponging miR-17-5p</p>
... related to that in matched negative control groups (Figure 4A and B). The MTT assay showed that the cell viability was notably decreased in si-PVT1 group, while BAMBI overex- pression reversed the inhibitory effect in ...
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Emerging role of LOXL2 in the promotion of pancreas cancer metastasis
... LOXL2, a member of the LOX family, is responsible for the stabilization of collagen and elastin fibers in ECM through covalent oxidative deamination. Tissue fibrosis is associated with cancer progression through direct ...
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Original Article CKIP-1 serves as a negative regulator and correlates with the degree of differentiation in gastric cancer
... and PI3K/Akt signaling, participate in the regu- lation of tumor stem cells [15, 16]. Recent stud- ies have demonstrated CKIP-1 as a tumor sup- pressor protein in various cancers, such as lung cancer [17]. However, the ...
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Cross-linked hyaluronic acid gel inhibits metastasis and growth of gastric and hepatic cancer cells: in vitro and in vivo studies
... cells. Migration and invasion assays, Western blotting, pull down assay, siRNA interference, and nude mice implantation tumor model were applied in this ...the migration and invasion ...
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<p>Circular RNA circHIPK3 promotes cell proliferation and invasion of prostate cancer by sponging miR-193a-3p and regulating MCL1 expression</p>
... the migration and Transwell assays results, we also demonstrated that MCL1 overexpression significantly increased the migration and invasion of PCa cells and that circHIPK3 knockdown significantly ...
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MiR-206 suppresses epithelial mesenchymal transition by targeting TGF-β signaling in estrogen receptor positive breast cancer cells
... Western blot analyses were done to further investigate the mechanism of how miR-206 regulates the migration and invasion of ER positive BC (Figure 2A). The expression of E-cadherin protein, an epithelial ...
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The Janus-faced roles of Krüppel-like factor 4 in oral squamous cell carcinoma cells
... Krüppel-like factor 4 (KLF4) is a zinc-finger transcription factor that regulates many essential processes, including development and cell differentiation, proliferation, and apoptosis. Along with these roles in normal ...
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SPANXA suppresses EMT by inhibiting c-JUN/SNAI2 signaling in lung adenocarcinoma
... vitro migration and matrigel invasion assay The migration and invasion abilities were determined using a Transwell apparatus without or with Matrigel-coated membranes (BD Biosciences, Franklin ...
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<p>UBE2T promotes proliferation via G2/M checkpoint in hepatocellular carcinoma</p>
... Results: In the present study, we reported that UBE2T mRNA and protein levels were signi fi cantly upregulated in HCC tissues compared to adjacent non-tumor tissues. Additionally, suppression of UBE2T expression inhibited ...
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