miR-106b
Original Article miR-106b promoted growth and inhibited apoptosis of nasopharyngeal carcinoma cells by suppressing the tumor suppressor PTEN
... cancer. miR-106b regulates p21/CDKN1A and promote cell cycle progression ...of miR-106b in conventional renal cell carcinoma is a potential marker for prediction of early metastasis after ...
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miR-93/miR-106b/miR-375-CIC-CRABP1: a novel regulatory axis in prostate cancer progression
... that miR-93, miR-106b, and miR-375, which are known to be frequently overexpressed in prostate cancer patients, cooperatively down-regulate CIC levels to promote cancer ...suggest ...
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Original Article In situ hybridization analysis of the expression of miR-106b in colonic cancer
... Switzerland) in which the following steps were performed: proteinase-K treatment 15 µg/ml at 37°C for 15 min, pre-hybridization in Exiqon hybridization buffer (Exiqon, Vedbæk, Denmark) at 50°C for 60 min,hybridization ...
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Original Article Expression levels and diagnostic values of miR-106b and miR-122 in different stages of laryngeal carcinoma
... that miR-122 could inhibit the metastasis of cells and epithelial-mesenchy- mal transition in non-small cell lung carcinoma ...that miR-106b and miR-122 were abnormally expressed in some ...
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Role of circulating miR 194-5p, miR 106b, and miR 146a as potential biomarkers for epilepsy: a case-control study
... by miR 146a and miR ...(miR 106b) which fights against another parallel antiepileptogenic mechanism represented by the antiepileptogenic miRNAs (miR 146a and miR ...
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Original Article The TNFα-miR-106b-5p-Caspase 9 axis functions as a key regulator in cerebral infarction via modulating endothelial cell apoptosis
... of miR-106b-5p was significantly downreg- ulated in serum samples derived from patients with cerebral infarction and MCAO model ...of miR-106b-5p in HUVECs. Importantly, ectopic expression of ...
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Hsa-miR-106b-5p Negatively Regulates LEF1
... Targetminer and miRDB were used to identify the putative targets of miR-106b. These bioinformatic approaches use several common criteria to judge whether certain transcript is a target for certain miRNA. ...
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Up-Regulation of miR-21, miR-25, miR-93, and miR-106b in Gastric Cancer
... for miR-21 were detected to be ...that miR-25 alone could achieve a suitable diagnosis accuracy to distinguish GC tissue from non-cancerous tissue, with sensitivity of ...of miR-21, miR-25, ...
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miR-106b-5p inhibits the invasion and metastasis of colorectal cancer by targeting CTSA
... of mir-106b-5p target genes in hcT116 and loVo cells using bioinformatics predictions and literature ...an mir-106b-5p-expressing lentivirus or a control lentivirus and in hcT8 cells ...
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MiR 106b induces cell radioresistance via the PTEN/PI3K/AKT pathways and p21 in colorectal cancer
... that miR-106b could enhance the cell self-renew capacity and upregulate the expres- sion of stem cell markers under both normal and radia- tion ...of miR-106b could induce cell ...When ...
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<p>miR-106b promotes proliferation and invasion by targeting Capicua through MAPK signaling in renal carcinoma cancer</p>
... includes miR-488, 10 miR-30a-5p, 11 miR-199b-5p 7 and so on, which contribute to RCC at different stages through regulating targeted oncogenes or tumor suppres- sor ...that miR-106b is ...
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Original Article Down-regualtion of miR-106b induces epithelial-mesenchymal transition but suppresses metastatic colonization by targeting Prrx1 in colorectal cancer
... during miR-106b-mediated EMT and conferred migratory and invasive properties as well as GTPases (Rac1 and ...during miR-106b-mediated cytoskeletal reorga- nization, migratory and ...
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MiR-106b promotes cell proliferation via targeting RB in laryngeal carcinoma
... The human RB 3’UTR (bases 813-959) were amplified and cloned into the XbaI site of the pGL3-control vec- tor (Promega, USA), downstream of the luciferase gene, to generate the plasmids pGL3-WT-RB-3 ’ UTR. pGL3- MUT-RB-3 ...
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Deletion of the Mir-106b~ 25 MicroRNA cluster attenuates atherosclerosis in Apolipoprotein E knockout mice
... the miR-106b~ 25 cluster in ApoE KO mice would have a functional effect on the progression of ...and miR-106b~ 25 KO (Double KO) mice and ApoE KO littermates, which served as controls, were ...
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Original Article C-myc-regulated miR-106b promotes proliferation of human bladder cancer cells by targeting DAPK2
... Methods. MiR-106b mimics or inhibitors were then transfected into the cells (Figure ...of miR-106b and DAKP2. A. Base sequence of miR-106b and ...the miR-106b group ...
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MiR-106b exhibits an anti-angiogenic function by inhibiting STAT3 expression in endothelial cells
... showed miR-17 family contributes to maintain the structure sta- bility of alveolar epithelial cells in growth and develop- ment process by targeting MAPK14 and STAT3 [17], meanwhile other evidence demonstrated ...
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Original Article Serum miR-106b upregulation predicts poor prognosis in patients with colorectal cancer
... that miR-106b exerted oncogenic prop- erties in various human ...that miR-106b was highly ex- pressed in tissues and cell lines of cervical can- ...Overexpressed MiR-106b, ...
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miR-106b regulates the proliferation and differentiation of neural stem/progenitor cells through Tp53inp1-Tp53-Cdkn1a axis
... of miR-106 in NPCs’ regulation, we carried out terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) assay, detecting DNA fragmentation by label- ing the terminal end of nucleic ...in ...
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MicroRNA-106b promotes colorectal cancer cell migration and invasion by directly targeting DLC1
... Moreover, miR- 106b-high/DLC1-low status was significantly associated with a shorter OS and a shorter ...that miR-106b represented an inde- pendent prognostic factor for both OS and ...of ...
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<p>MicroRNA-106b-5p promotes hepatocellular carcinoma development via modulating FOG2</p>
... a miR-106b-5p-binding ...and miR-106b-5p mimics were both signi fi cantly lower than those in control groups (both ...and miR-106b-5p mimics were cotransfected (Figure ...
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