miR-106b-25 cluster
Deletion of the Mir-106b~ 25 MicroRNA cluster attenuates atherosclerosis in Apolipoprotein E knockout mice
... the miR-106b~ 25 cluster could in- fluence plasma cholesterol levels by targeting genes pertaining to cholesterol biosynthesis and/or ...the miR-106b~ 25 cluster ...
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miR-106b regulates the proliferation and differentiation of neural stem/progenitor cells through Tp53inp1-Tp53-Cdkn1a axis
... Recently, miR-17 ~ 106 family was reported to regulate neurogenesis of mouse developing/adult NPCs or ESC-derived NPCs [8, 15, ...that miR-17 ~ 106 family serves as a cell cycle facilitator, mostly in ...
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MiR-106b exhibits an anti-angiogenic function by inhibiting STAT3 expression in endothelial cells
... turn, miR-106b and miR-93 regulated E2F1 ...Interestingly, miR-17 ~ 92 cluster synergistically participates in this ...stated, miR- 17 ~ 92 cluster has been proven pivotal ...
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MiR-106b promotes cell proliferation via targeting RB in laryngeal carcinoma
... of miR- 106b-25 ...of miR-106b, such as p21/CDKN1A and TGF- b type II receptor (T b R ...that miR-106b gain of function promotes cell cycle progression, whereas loss of ...
6
C-Myc-dependent repression of two oncogenic miRNA clusters contributes to triptolide-induced cell death in hepatocellular carcinoma cells
... The complementary DNA encoding ERCC3 and c-Myc was PCR-amplified by the Pfu Ultra II Fusion HS DNA Polymerase (Agilent Technologies, Palo Alto, CA), and was subcloned into the pcDNA3.1 vector (Invitrogen, Carlsbad, CA). ...
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MicroRNA-106b is involved in transforming growth factor β1–induced cell migration by targeting disabled homolog 2 in cervical carcinoma
... the miR-106b ~ 25 cluster, which is homologous to the miR-17 ~ 92 cluster known as an oncogenic miRNA ...that miR-106b is involved in the regulation of invasion and ...
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Upregulation of microRNA-106b is associated with poor prognosis in hepatocellular carcinoma
... the miR-106b ~ 25 cluster, which consists of miR-106b, miR-93 and miR-25, that is encoded within intron 13 of the minichromosome maintenance complex ...
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Intrinsic expression of host genes and intronic miRNAs in prostate carcinoma cells
... the miR 17–92 cluster, the expression profile of all the six member miRNAs in androgen-dependent MDA PCa 2b cells is significantly distinguishable from that in another androgen-dependent cell line, LNCaP ...
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Hsa-miR-106b-5p Negatively Regulates LEF1
... miRNA cluster, has been reported to be overexpressed in a wide variety of human ...cancers. miR-106b and miR-25, which belong to miR-17-92 paralog cluster, are ...
6
Multivariate analysis of clinicopathological and prognostic significance of miRNA 106b~25 cluster in gastric cancer
... and miR- NAs expression in this study, and in purpose of extract the important variable for the ...miRNA 106b~25 expression, T stage, N stage, TNM stage were in simi- lar location and correlated with ...
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Original Article The TNFα-miR-106b-5p-Caspase 9 axis functions as a key regulator in cerebral infarction via modulating endothelial cell apoptosis
... The miR-106 family contains two members, miR-106a and miR-106b, in which miR-106a has been reported to be deregulated in isch- emic ...ischemia, miR-106a is activated in the ...
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Role of circulating miR 194-5p, miR 106b, and miR 146a as potential biomarkers for epilepsy: a case-control study
... of miR 146a in epileptogenesis was studied and it was related to the regulation of inflammation [16, 35] and the immune system [36, ...of miR 146a through negative regulation of inflam- mation via ...
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Original Article Expression levels and diagnostic values of miR-106b and miR-122 in different stages of laryngeal carcinoma
... of miR-106b and miR-122 in different stages of laryngeal carcinoma ...of miR-106 and miR- 122 in carcinoma tissues and sera of all included subjects were detected using qRT-PCR ...of ...
7
Potential microRNA-related targets in clearance pathways of amyloid-β: novel therapeutic approach for the treatment of Alzheimer’s disease
... that miR-181c suppressed the activity of the luciferase reporter plas- mid containing TLR4 3 ′ -UTR by reducing TLR4 mRNA and protein expression in microglial ...Consequently, miR-181c inhibited the ...
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miR-93/miR-106b/miR-375-CIC-CRABP1: a novel regulatory axis in prostate cancer progression
... that miR-93, miR-106b, and miR-375, which are known to be frequently overexpressed in prostate cancer patients, cooperatively down-regulate CIC levels to promote cancer ...suggest ...
15
Functional similarities of microRNAs across different types of tissue stem cells in aging
... vivo. miR-17 and its paralogues miR-106a and 106b (miR-17/106) regulate not only dif- ferentiation potential but also expression of some secretory factors, including Gdf6, and are implicated ...
5
Original Article In situ hybridization analysis of the expression of miR-106b in colonic cancer
... of miR-106b lev- els between colonic tissues and para-cancer- ous tissues was statistically ...The miR-106b levels were not quite correlated with clinic-pathological characteristics and ...
7
MiR 106b induces cell radioresistance via the PTEN/PI3K/AKT pathways and p21 in colorectal cancer
... that miR-106b could enhance the cell self-renew capacity and upregulate the expres- sion of stem cell markers under both normal and radia- tion ...of miR-106b could induce cell ...When ...
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<p>miR-106b promotes proliferation and invasion by targeting Capicua through MAPK signaling in renal carcinoma cancer</p>
... that miR-142-5p pro- moted the proliferation and migration of RCC cells by targeting ...use miR-146a to reduce or abolish the endogenous NO production to escape macrophage-mediated cell ...proved ...
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Cytoplasmic p21 expression levels determine cisplatin resistance in human testicular cancer
... including miR-17~92 and miR-106a~363 cluster of the miR-106b seed family ...Oct4, miR-106b, and p21 expres- sion in ...of miR-106a, miR-17-5p, and ...
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