mir-140
<p>CircRNA SMARCC1 Sponges MiR-140-3p to Regulate Cell Progression in Colorectal Cancer</p>
... Many studies showed that circRNA is closely related to CRC progression. The circRNA/miRNA/mRNA axis plays a critical role in CRC carcinogenesis, providing novel insights into the pathogenesis of CRC. In this study, we ...
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Original Article Identification of miR-140-3p as a marker associated with poor prognosis in spinal chordoma
... on miR-140-3p because there is evidence sug- gesting that miR-140-3p was significantly up- regulated in skull base chorodma compared with normal tissues ...Moreover, miR-140- 3p ...
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<p>Long Noncoding RNA H19 Facilitates Small Cell Lung Cancer Tumorigenesis Through miR-140-5p/FGF9 Axis</p>
... of miR-140-5p. MiR-140- 5p has previously been documented as a tumor suppressor gene in many ...of miR-140-5p in SCLC, which has been reported as a notable oncogene in several ...
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Original Article Diesel exhaust particles induce toxicity to beta cells by suppressing miR-140-5p
... of miR-140-5p in beta cells was gradual- ly decreased following DPE ...of miR-140-5p reduced the oxida- tive stress levels, promoted cell survival, and protected the insulin secretion function ...
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<p>lncRNA <em>MALAT1</em> potentiates the progression of tongue squamous cell carcinoma through regulating <em>miR-140-5p</em>-PAK1 pathway</p>
... increased miR-140-5p expression (Figure 6E), and decreased PAK1 expression (Figure 6F) were observed in MALAT1-silenced xenograft tumors of ...via miR-140-5p/PAK1 regulatory axis in ...
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MicroRNA miR 320a and miR 140 inhibit mink enteritis virus infection by repression of its receptor, feline transferrin receptor
... Since miR-320a and miR-140 have been shown to in- hibit MEV entry into host cells and might also affect virus replication, it may find application as an antiviral therapeutic for MEV-induced mink ...
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Regulation of the IGFBP 5 and MMP 13 genes by the microRNAs miR 140 and miR 27a in human osteoarthritic chondrocytes
... miRNA was extracted with the mirVana kit (Ambion, Aus- tin, TX, USA). This kit is designed especially for the isola- tion of small RNAs by enriching the population of RNAs that are 200 bases and smaller. The extracted ...
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NFAT3 and TGF β/SMAD3 regulate the expression of miR 140 in osteoarthritis
... of miR-140 ...and miR-140 were reported to be co-expressed and activated by Sox9 [33] and Sox9 is up- regulated by osmotic stress in human chondrocytes ...down-regulate miR-140 ...
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Original Article MiR-140-5p suppresses the adipogenic differentiation of mesenchymal stem cells in rats with steroid-induced osteonecrosis of the femoral head
... ATRA, miR-NC, or siRNA-miR-140-5p were simultaneously ...group, miR-NC, siRNA-miR-140-5p, ATRA alone, ATRA + miR- NC, and ATRA + ...
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E2 regulates MMP 13 via targeting miR 140 in IL 1β induced extracellular matrix degradation in human chondrocytes
... of miR-140 promoter activity, SW1353 human chondrosar- coma cells were transiently transfected using Lipofecta- mine 2000 (Invitrogen) according to the manufacturer’s ...
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Original Article miR-140-5p inhibits proliferation, invasion, and promote apoptosis of non-small cell lung cancer cells through targeted inhibition of Wnt signaling pathway
... family, miR-140- 5p regulates a variety of life ...that miR-140-5p inhibited the prolif- eration and invasion of tumor cells as well as the occurrence of NSCLC [27, ...with ...
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Long noncoding RNA SNHG16 induces sorafenib resistance in hepatocellular carcinoma cells through sponging miR-140-5p
... The miR-140-5p mimics, mimics control, miR-140-5p inhibitor, and inhibitor control were obtained from Guangzhou RiboBio (RiboBio, PR ...
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<p>miR-140-3p Suppresses Cell Growth And Induces Apoptosis In Colorectal Cancer By Targeting PD-L1</p>
... of miR-140-3p is associated with activation of the AKT/mTOR signalling ...for miR-140-3p involves suppression in CRC ...that miR-140-3p plays a pivotal role in the development ...
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Up-regulated lncRNA XIST contributes to progression of cervical cancer via regulating miR-140-5p and ORC1
... of miR-6852 could lead to arrest the cell cycle in G2/M phase and induce necrosis in cervical cancer cell ...of miR-140-5p was closely related to cervical tumor growth and metas- tasis ...that ...
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Inhibition of colorectal cancer stem cell survival and invasive potential by hsa-miR-140-5p mediated suppression of Smad2 and autophagy
... of miR-34a decreased the proliferative and migratory potential of these cells through Akt and Wnt signaling pathways ...hsa-miR- 140-5p in ...
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miR 140 3p Knockdown Suppresses Cell Proliferation and Fibrogenesis in Hepatic Stellate Cells via PTEN Mediated AKT/mTOR Signaling
... of miR- NAs in liver fibrosis and miRNAs, and not surprisingly, both play an anti-fibrogenic and a pro-fibrogenic role, depending on the genes targeted and the nature of the ...that miR-140-3p is ...
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<p>miR-140-5p alleviates the aggressive progression of Wilms’ tumor through directly targeting <em>TGFBR1</em> gene</p>
... which, miR-140-5p was identified to be obviously down-regulated in WT tissues, and the AUC of it was ...with miR-140-5p low expression always had a shorter overall survival and more aggressive ...
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Exosomes derived from miR-140-5p-overexpressing human synovial mesenchymal stem cells enhance cartilage tissue regeneration and prevent osteoarthritis of the knee in a rat model
... 5. miR-140-5p maintains the function of articular chondrocytes (A) Normalized gene expression levels in SMSC-Exos detected by miRNA ...of miR-140-5p and ...with miR-140-5p, RalA ...
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Original Article Downregulation of serum miR-140-5p predicts poor prognosis of patients with colorectal cancer
... of miR- 140-5p in the serum samples was detected using an ABI PRISM 7500 Sequence Detection System (Applied ...in miR-140-5p expression were determined using the 2 -ΔΔCT method with the U6 ...
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Serum microRNA array analysis identifies miR-140-3p, miR-33b-3p and miR-671-3p as potential osteoarthritis biomarkers involved in metabolic processes
... receptor 1 (T GFβR1) , cAMP responsive element binding protein 5 ( CREB5), nuclear factor kB (NFkB), and tumor necrosis factor a (TNFa), genes enriched in inflammatory and metabolic processes as revealed by pathway ...
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