miR-140-5p
Original Article Diesel exhaust particles induce toxicity to beta cells by suppressing miR-140-5p
... of miR-140 was significantly reduced in T2D rats, indicating that downregulation of miR-140 might promote the progression of T2D ...of miR-140-5p in beta ...increase ...
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Original Article MiR-140-5p suppresses the adipogenic differentiation of mesenchymal stem cells in rats with steroid-induced osteonecrosis of the femoral head
... of miR- 140-5p expression inhibition and/or ATRA treatment on the adipogenic differentiation of MSCs were then ...that miR-140-5p expression inhibition or ATRA treatment resulted ...
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<p>lncRNA <em>MALAT1</em> potentiates the progression of tongue squamous cell carcinoma through regulating <em>miR-140-5p</em>-PAK1 pathway</p>
... a miR-140-5p sponge to exert its oncogenic effects was further explored in ...and miR-140-5p (Figure ...of miR-140-5p markedly attenuated luciferase activity ...
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<p>Long Non-Coding RNA TMPO-AS1 Promotes Cell Migration and Invasion by Sponging miR-140-5p and Inducing SOX4-Mediated EMT in Gastric Cancer</p>
... to miR-140-5p by bioinformatics analysis through Starbase database ...with miR-140-5p mimics in HEK293T cells (Figure ...that miR-140-5p was signi fi cantly ...
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<p>Long Non-Coding RNA HCP5 Facilitates Cell Invasion And Epithelial-Mesenchymal Transition In Oral Squamous Cell Carcinoma By miR-140-5p/SOX4 Axis</p>
... for miR-140-5p in ...between miR-140-5p and ...and miR-140-5p mimics or NC. (C) RT-qPCR analysis of miR-140-5p expression levels in ...
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<p>Long Noncoding RNA H19 Facilitates Small Cell Lung Cancer Tumorigenesis Through miR-140-5p/FGF9 Axis</p>
... through miR-140-5p/FGF9 ...group, miR-140-5p inhibitor group, siH19 and miR-140-5p inhibitor group, GAPDH acted as reference ...that ...
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LncRNA H19 promotes odontoblastic differentiation of human dental pulp stem cells by regulating miR-140-5p and BMP-2/FGF9
... Background: Increasing evidence has revealed that long non-coding RNAs (lncRNAs) exert critical roles in biological mineralization. As a critical process for dentin formation, odontoblastic differentiation is regulated ...
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Inhibition of colorectal cancer stem cell survival and invasive potential by hsa-miR-140-5p mediated suppression of Smad2 and autophagy
... hsa-miR- 140-5p in CSCs abolished tumor formation and metastasis in ...hsa- miR-140 expression is significantly correlated with better survival in stage III and IV colorectal cancer ...
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Exosomes derived from miR-140-5p-overexpressing human synovial mesenchymal stem cells enhance cartilage tissue regeneration and prevent osteoarthritis of the knee in a rat model
... 5. miR-140-5p maintains the function of articular chondrocytes (A) Normalized gene expression levels in SMSC-Exos detected by miRNA ...of miR-140-5p and ...with ...
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Original Article miR-140-5p inhibits proliferation, invasion, and promote apoptosis of non-small cell lung cancer cells through targeted inhibition of Wnt signaling pathway
... of miR-140-5p on proliferation, invasion and apoptosis of non-small cell lung cancer (NSCLC) cells through Wnt signaling ...group, miR-140-5p mimic group, pcDNA3.1-Wnt1 group and ...
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<p>miR-140-5p alleviates the aggressive progression of Wilms’ tumor through directly targeting <em>TGFBR1</em> gene</p>
... Background and objective: Although many miRNAs are identified to be deregulated and play vital roles in the progression of Wilms’ tumor (WT), there are still a large number of miRNAs are waiting for us to explore. The ...
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Original Article Downregulation of serum miR-140-5p predicts poor prognosis of patients with colorectal cancer
... findings, miR-140-5p ex- pression was reduced in CRC tissue samples and it expression level was associated with poor prognosis of ...of miR-140-5p suppressed the prolifera- tion, ...
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Up-regulated lncRNA XIST contributes to progression of cervical cancer via regulating miR-140-5p and ORC1
... In present study, we firstly analyzed the differentially expressed lncRNA, miRNA and mRNA between matched normal adjacent samples and tumor (CESC) samples. Then, the similarities between tumor samples and nor- mal ...
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Long noncoding RNA SNHG16 induces sorafenib resistance in hepatocellular carcinoma cells through sponging miR-140-5p
... and miR-140-5p expression levels in tissue samples and cells were detected by RT-qPCR ...and miR-140-5p was validated by dual luciferase reporter assay and biotinylated RNA ...
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miR-140-5p regulates the odontoblastic differentiation of dental pulp stem cells via the Wnt1/β-catenin signaling pathway
... researchers. miR-140-5p is a member of the micro- RNAs ...that miR- 140-5p is involved in the proliferation and differenti- ation of cells ...
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MicroRNA 140 5p and SMURF1 regulate pulmonary arterial hypertension
... of miR-140-5p is reduced in patients with ...of miR in patients with disease prior to the initiation of drug therapy, we performed real-time quantita- tive PCR (qPCR) array studies (TaqMan ...
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MicroRNA-140-5p inhibits salivary adenoid cystic carcinoma progression and metastasis via targeting survivin
... of miR-155 in SACC tissues and found that miR-155 facilitated cell cycle progression and enhanced invasion of ...SACC. MiR-181a was found to be down-regulated in SACC cells with higher metastatic ...
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Role of circulating miR 194-5p, miR 106b, and miR 146a as potential biomarkers for epilepsy: a case-control study
... kinases; miR: MicroRNA; miRNA: MicroRNA; mRNA: Messenger RNA; mTOR: Mammalian target of rabamycin; NF- B: Nuclear factor kappa-B; OR: Odds ratio; qRT-PCR: Real-time quantitative polymerase chain reaction; RNA: ...
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Tumor-suppressor role of miR-139-5p in endometrial cancer
... example, miR-10b inhibits apop- tosis and promotes proliferation and invasion of EC cells via targeting HOXB3 ...[7]. MiR-135b can target FOXO1 to promote cell proliferation in EC cells ...
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Regulation of the IGFBP 5 and MMP 13 genes by the microRNAs miR 140 and miR 27a in human osteoarthritic chondrocytes
... both miRNAs are expressed in human OA chondrocytes at about the same level as the RNU24 control gene, which was given an arbitrary value of 1. Values of 0.88 and 0.94 fold change were recorded for miR-140 ...
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