miR-141
miR-141-3p is a key negative regulator of the EGFR pathway in osteosarcoma
... of miR-141-3p in osteosarcoma was detected by RT-PCR assay, which showed that the expression of miR-141-3p in osteosarcoma was low (Figure ...higher miR-141-3p expression had ...
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Original Article miR-200a/miR-141 and miR-205 upregulation might be associated with hormone receptor status and prognosis in endometrial carcinomas
... of miR-200a/miR-141 and miR- 205 expression in endometrioid carcinomas (ECs) versus nonendometrioid carcinomas (NECs) and to assess their correlation with hormone receptor ...status. ...
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Evaluation of miR-141, miR-200c, miR-30b Expression and Clinicopathological Features of Bladder Cancer
... Studies have reported that miRNA play important roles in the pathophysiology of BC. MiRNA may contribute to tumorigenesis and help in molecular diagnosis, prognosis and targeted therapy (33-35). However, limited studies ...
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Clinical Correlation of miR-200c/141 Cluster DNA Methylation and miR-141 Expression with the Clinicopathological Features of Colorectal Primary Lesions/Tumors
... The miR-200 family members are grouped into potent tumor-suppressive miRNAs ...(12). MiR-141, an miR-200 family member, is located with miR- 200c on chromosome 12 ...(13). ...
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WIPF1 antagonizes the tumor suppressive effect of miR-141/200c and is associated with poor survival in patients with PDAC
... the miR-200 family members miR-200a/200b/429 and miR-200c/141 using the MassARRAY compact system with MALDI-TOF mass spectrometry which permits high-throughput identification of methylation ...
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Epigenetic modification of miR-141 regulates SKA2 by an endogenous ‘sponge’ HOTAIR in glioma
... of miR-141 has recently implicated in the occurrence and development of various types of malignant ...of miR-141 in the pathogenesis of glioma remains ...that miR-141 was ...
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The miR-141/neuropilin-1 axis is associated with the clinicopathology and contributes to the growth and metastasis of pancreatic cancer
... ANOVA: analysis of variance; EdU: 5-ethynyl-2′-deoxyuridine; CDK: cyclin- dependent kinase; EGF: epithelial growth factor; EGFR: epithelial growth factor receptor; ERK: extracellular-signal-regulated kinase; FAK: focal ...
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Original Article MiR-141 inhibits colorectal cancer cell proliferation and invasion by targeting PRKAR1A
... the miR-141 seed sequence in the 3’UTR of PRKAR1A (Mut) was performed using the QuikChange™ Site-Directed Mutagenesis Kit (Stratagene, La Jolla, CA, ...nM miR-141 mimics or scrambled ...
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Original Article Inhibition of RIPK1 expression and facilitation of TRAIL-induced hepatocellular carcinoma cell apoptosis by miR-141
... lowered miR-141 expression in HCC tumor tis- sues [16, 17], thus indicating possible tumor- suppressor role of miR-141 in HCC pathogene- ...ween miR-141 and 3’-untranslated ...
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Activation of the LINC00242/miR-141/FOXC1 axis underpins the development of gastric cancer
... overlap miR-141 in the poorly expressed miRNAs from the GSE26595 data- set and the RAID ...of miR-141 were predicted by the mirDIP, TargetScan and DIANA data- ...through miR-141, ...
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Tumor-suppressing miR-141 gene complex-loaded tissue-adhesive glue for the locoregional treatment of hepatocellular carcinoma
... introduced miR-141 in the form of NPX-glue and examined the efficiency of gene delivery and the tumor suppressive effects of miR-141 in HCC cells implanted in ...delivered ...
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Original Article miR-141 promotes differentiation of adipocyte and contributes to the obesity by targeting to FOXA2
... 3T3-L1 fibroblasts cells (ATCC, Manassas, VA) were maintained in Dulbecco’s modified Eagle’s medium (DMEM, Gibco) supplemented with 10% FBS (Gibco), 100 U/ml penicillin and 100 mg/ml streptomycin at 10% CO 2 and 37°C. ...
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Exosomal transfer of obesity adipose tissue for decreased miR-141-3p mediate insulin resistance of hepatocytes
... of miR-141-3p in Ob- and HFD-exosomes were significantly lower than ...WT-exosomes. MiR-141-3p can be effectively delivered into AML12 cells accompanied by the absorption of exosomes, but the ...
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LncRNA SNHG15 contributes to proliferation, invasion and autophagy in osteosarcoma cells by sponging miR-141
... and miR-141 on biological functions of OS ...while miR-141 suppressing dramatically re- cuperated this decrease of cell ...that miR-141 conspicuously inhibited the promotion of ...
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Role of DNA methylation in miR 200c/141 cluster silencing in invasive breast cancer cells
... both miR- NAs as it was detected using both primers and it is located in a region that is highly conserved among ...containing miR-200c, but not ...out miR-141 and conserves the ...
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Original Article Functional synergy between microRNAs in nasopharyngeal carcinoma
... and miR-203 and miR-526b shared the most common target genes ...and miR-139-5p and miR-141 shared the most common GO terms ...conclusions, MiR-141 and miRNA-138 may have ...
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Deep sequencing reveals microRNAs predictive of antiangiogenic drug response
... tumor miR- NAs that, through quantitative PCR (qPCR), analyzed metastatic ccRCC cases treated with ...that miR-221/222 was associated with the patients’ progression-free survival (PFS) (17), another on 20 ...
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A miR-200c/141-BMI1 autoregulatory loop regulates oncogenic activity of BMI1 in cancer cells
... IH, miR-200c IH and miR-141 IH breast cancer cells ...of miR-200c and ...of miR-200c and miR-141 in control IH but not in miR-200c IH and miR-141 IH ...
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The miR-200 family: multiple effects on gliomas
... the miR-200 family, as epigenetic regulatory molecules, can regulate physiological and pathological processes through targeting multiple downstream genes, consequently affecting prolif- eration and invasion of ...
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Original Article Expression of microRNA-141 in the urine, serum, and kidneys of patients with IgA nephropathy
... the miR-200 family (for example, miR-141) can repress epithelial-mesenchymal transition (EMT) via downregulation of ZEB1 and ZEB2, two major transcriptional repres- sors of ...of ...
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