miR-16-1-3p
miR-15a-3p and miR-16-1-3p Negatively Regulate Twist1 to Repress Gastric Cancer Cell Invasion and Metastasis
... of miR-15a-3p and miR-16-1-3p in the regulation of Twist1 expression and EMT ...for miR-15a-3p and miR-16-1-3p ...of ...
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p62 acts as an oncogene and is targeted by miR-124-3p in glioma
... To investigate the relationship between glioma malig- nancy and the expression of p62, we analysed the expres- sion of p62 with IHC, western blot and qRT-PCR. First, we used qRT-PCR to qualify the expression of p62 mRNA ...
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High expression of miR-222-3p in children with Mycoplasma pneumoniae pneumonia
... example, miR-125a-3p pro- motes THP-1 macrophages differentiation and apoptosis by down-regulating NF1 and Bcl-2 ...[17]. MiR-125b and let7b can regulate macrophage cytokine production in- ...
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Fatty acid synthase is a primary target of MiR-15a and MiR-16-1 in breast cancer
... them, miR-15a and miR-16-1 have the same seed sequence and exert their tumor suppressive activities through inhibiting multiple proliferative or oncogenic genes, such as Bcl-2, cyclin D1 and ...
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Loss of miR 542 3p enhances IGFBP 1 expression in decidualizing human endometrial stromal cells
... miRNA expression array. The analysis of the miRNA microarray was performed using a commercial human miRNA microarray (G4872A Human Rel. 16.0, Agilent Technologies, Santa Clara, CA, USA), which included probes for 1,205 ...
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The inverted pattern of circulating miR-221-3p and miR-222-3p associated with isolated low HDL-C phenotype
... file 1: Table S1) were screened from ap- proximately more than 400 participants from Healthy Check-up Department during August, 2014 to Novem- ber, ...file 1: Table S1, three of 15 non-HDL pa- rameters ...
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MiR-497-5p, miR-195-5p and miR-455-3p function as tumor suppressors by targeting hTERT in melanoma A375 cells
... Figure 1, the expression level of miR-497-5p, miR-195-5p and miR-455-3p were statistically significantly downregulated, whereas miR-424-5p and miR-212-5p were ...
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miR-328-3p mediates the anti-tumor effect in osteosarcoma via directly targeting MMP-16
... To determine the expression of protein in cells, west- ern blot was performed. First, ice-cold PBS was applied to wash the cells and total proteins were extracted from MG-63 cells with a radioimmunoprecipitation assay ...
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NFATc3-dependent expression of miR-153-3p promotes mitochondrial fragmentation in cardiac hypertrophy by impairing mitofusin-1 expression
... example, miR-378 inhibits cardiac hypertrophy by suppressing myocardial fibrosis through a paracrine mechanism ...[16]. miR-99a blocks physiological cardiac hypertrophy by downregulating the mTOR ...
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MiR-142-3p Regulates Cardiovascular System during Zebrafish Development
... of miR-155, miR-451, and miR-320 has been shown to result in blood diseases ...fish miR-142-3p is specifically expressed in the hematopoietic tissue, co-transcribed with miR-451, ...
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<p>miR-1-3p suppresses the epithelial-mesenchymal transition property in renal cell cancer by downregulating Fibronectin 1</p>
... that miR-1, a homologous analog of mir-1-3p, may re fl ect RCC ...heterogeneity. 16 Kawakami et al, 17 speculated through preliminary in vitro experiments that mirR-1 might ...
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miR-29b-3p regulated osteoblast differentiation via regulating IGF-1 secretion of mechanically stimulated osteocytes
... mouse miRNAs of Sanger miRBase 19. Data were acquired using Agilent Feature Extraction software version 10.7 (Agilent, Palo Alto, CA, USA) [16, 17]. Further data analyses were per- formed using GeneSpring GX 10.0 ...
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Circulating MiR-16-5p and MiR-19b-3p as Two Novel Potential Biomarkers to Indicate Progression of Gastric Cancer
... Gastric cancer (GC) is currently the fourth most common cancer and the second leading cause for cancer-related deaths worldwide [1]. According to the annual report on status of cancer in China in 2010 [2], GC was ...
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Hsa_circ_0011385 accelerates the progression of thyroid cancer by targeting miR-361-3p
... by miR-361-3p. BCPAP cells were transfected with miR-361-3p mimics and/or hsa_circ_0011385 plasmid, ...a miR-361-3p expression was determined by qRT-PCR assay in each group (**P ...
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MiR-369-3p participates in endometrioid adenocarcinoma via the regulation of autophagy
... of miR- 369-3p increases in the skin tissues of psoriasis patients [19] and that the aberrant expression of miR-369-3p cor- relates with disease severity in hepatocellular carcinoma ...that ...
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The putative tumour suppressor miR-1-3p modulates prostate cancer cell aggressiveness by repressing E2F5 and PFTK1
... of miR-1-3p upregulation by the miR- 1-3p mimic, and knockdown by the miR-1-3p inhibitor was confirmed by quantifying the transcription levels of ...
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<p>MiR-124-3p.1 Sensitizes Ovarian Cancer Cells to Mitochondrial Apoptosis Induced by Carboplatin</p>
... express miR-124-3p.1, and 5×10 6 lentivirus-transfected SKOV3 cells were inocu- lated subcutaneously into BALB/c nude mice (Shanghai Super-B&K Laboratory Animal ...
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Downregulation of miR-137 and miR-6500-3p promotes cell proliferation in pediatric high-grade gliomas
... of miR-137 and ...and miR-137 expression (-0.4051), KIF14 and miR-6500- 3p expression ...and miR-6500-3p Table 1: Overview of the pediatric patients with LGG and ...
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Methylation-mediated silencing of miR-133a-3p promotes breast cancer cell migration and stemness via miR-133a-3p/MAML1/DNMT3A positive feedback loop
... Female BALB/c nude mice (5–6 weeks old, 18–20 g) were purchased from the Model Animal Research Center at Nanjing University (Nanjing, China) and kept under specific pathogen-free (SPF) conditions at China Pharmaceutical ...
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MiR-27a-3p functions as an oncogene in gastric cancer by targeting BTG2
... between miR-27a and BTG2 in gastric cancer has not been ...mature miR-27a, miR-27a-5p and miR-27-3p, were both frequently overexpressed in gastric cancer tissues and cell lines, whereas ...
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