miR-17
Prognostic value of miR-17-5p in cancers: a meta-analysis
... high miR-17-5p expression was not the same across studies; thus, it was difficult to define miR-17-5p overexpres- sion in various ...high miR-17-5p ...
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Stress Response of Glioblastoma Cells Mediated by miR-17-5p Targeting PTEN and the Passenger Strand miR-17-3p Targeting MDM2
... cells. MiR-17 therefore can induce chemo-resistance on glioblastoma cells by slowing down their ...simultaneously, miR-17 could act through several modes to regulate stress ...and ...
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miR-17 promotes expansion and adhesion of human cord blood CD34+ cells in vitro
... with 17/OE or 17/KD CD34 + cells to those injected with CTRL ...the 17/OE or 17/KD group with the corresponding CTRL group ...the 17/OE group compared to that in the CTRL ...the ...
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Control of oligodendroglial cell number by the miR 17 92 cluster
... of miR-19 [TargetScanS ...The miR-17-92 cluster regulates oligodendrocyte cell ...against miR-17 and miR-19b (anti-17-19b) were expressed in the mouse oligodendroglial ...
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The RNA binding protein bicaudal C regulates polycystin 2 in the kidney by antagonizing miR 17 activity
... Wang et al., 2002; Cogswell et al., 2003; Suh et al., 2006; Tran et al., 2007; Maisonneuve et al., 2009). Here, we extend previous studies that showed that Bicc1 is required for the proper development of the mouse ...
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MiR-17-5p regulates cell proliferation and migration by targeting transforming growth factor-β receptor 2 in gastric cancer
... Total RNA was isolated from the cultured cells and tissues using TRIzol reagent (Invitrogen, USA) according to the manufacturer’s protocol. RNA concentrations were determined spectrophotometrically. RNA quality was ...
11
miR-17 regulates melanoma cell motility by inhibiting the translation of ETV1
... The current knowledge about the role of ETV1 and mechanism in melanoma is very limited. A recent study showed a small subset of melanomas (5.3%), which over-expresses ETV1 [43]. Another work has identified copy gains of ...
11
miR-17 as a diagnostic biomarker regulates cell proliferation in breast cancer
... The significance of differences between groups was esti- mated by the Wilcoxon test for two-group comparisons and the Kruskal–Wallis test for k-group comparisons (with k.2). Cases were divided into two groups, high or ...
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A functional polymorphism in the promoter of miR-17-92 cluster is associated with decreased risk of ischemic stroke
... of miR-17 and miR-20a were found to associated with inhibit Hif mRNA and protein expression, this finding indicated that these two miRNAs may play role in atherosclerosis progression ...of ...
11
The miR 30 miRNA family regulates Xenopus pronephros development and targets the transcription factor Xlim1/Lhx1
... of miR-30a-5p -mediated ...strong miR-30 binding sites in the Lhx1 3 ⬘ ...the miR-30 binding sites in human, mouse and Xenopus Xlim1/Lhx1. The miR-30 seed sequences are indicated in ...a ...
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Evolutionary Conservation of Primate Lymphocryptovirus MicroRNA Targets
... removes 17 of the 22 BART miRNAs, leaving only five BART miRNAs and the BHRF1 miRNAs ...regulated miR-17/20/106 family, in the LMP1 and BHRF1 3=UTRs ...the miR- 17/20/106 binding sites ...
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Temporal regulation of HIF-1 and NF-κB in hypoxic hepatocarcinoma cells
... overexpressed miR-18a, miR-17, miR-93, and miR-199a- 5p in HepG2 cells and determined the mRNA and protein levels of HIF-1α after cells were exposed to hypoxia for 4 ...Intriguingly, ...
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Quantifying the prognostic significance of microRNA-17/17-5P in cancers: a meta-analysis based on published studies
... different miR-17/17-5P expression, but the actual values may be discrepant due to different algorithms and result in some ...of miR-17/17-5P for Begg’s 28 test and ...
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The VHL-dependent regulation of microRNAs in renal cancer
... IDs: miR-210: 000512, miR-155: 000479, miR-21: 000397, miR-31: 001100, miR-20a: 000580, miR-18a: 002422, miR-17: 000393, let-7i: 002221, miR-193b: 001010; ...
17
Bmp signaling represses Vegfa to promote outflow tract cushion development
... 3. miR-17/20a are downstream effectors of Bmp ...conserved miR-17/20a binding site ...92, miR-17 and miR-20a in the OFT of Bmp4/7 dCKO mouse ...of miR-17-92 ...
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Original Article A three-miRNA signature as a potential biomarker for the diagnosis of glioma
... of miR-17, miR-130a, and miR-10b were markedly increased in the plasma of gliomas compared to in healthy individuals (all ...of miR-17, miR-130a, and miR-10b was ...
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Screening miRNAs for early diagnosis of colorectal cancer by small RNA deep sequencing and evaluation in a Chinese patient population
... miRNAs, miR-18a-5p and miR-21-3p were significantly upregulated in adenomas and cancer tissues, compared with the normal mucosa; miR-135b-5p, miR-17-5p, miR-182-5p, ...
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Functional similarities of microRNAs across different types of tissue stem cells in aging
... including miR-17 family, miR- 125b, and miR-181 family members, show similar expres- sion pattern, namely they are expressed at higher levels dur- ing proliferating phase and downregulated ...
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C-Myc-dependent repression of two oncogenic miRNA clusters contributes to triptolide-induced cell death in hepatocellular carcinoma cells
... that miR-17-92 and its paralog miR- 106b-25 played an important role in ...the miR-17-92 and miR-106b-25 expression in HepG2 cells was significantly higher than that in immor- ...
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MiR-424 and miR-155 deregulated expression in cytogenetically normal acute myeloid leukaemia: correlation with NPM1 and FLT3 mutation status
... (miR-424, miR-155, miR-223, miR-17-5p) in 48 patients with cytogenetically normal AML well characterized for NPM1 and/or FLT3 ...that miR-424 was down-modulated in AMLs with ...
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