miR-19a
PPARα, a predictor of patient survival in glioma, inhibits cell growth through the E2F1/miR-19a feedback loop
... PPARα. MiR-19a was an important mediator between E2F1 and PPARα through qRT-PCR, Western blot, and luciferase reporter ...Increased miR-19a expression largely blocked the effect of si-E2F1 on ...
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MiR 19a, miR 122 and miR 223 are differentially regulated by hepatitis B virus X protein and involve in cell proliferation in hepatoma cells
... suppressive. MiR-19a has been found to promote cell proliferation in various types of cancers such as bladder cancer, gastric cancer, prostate can- cer via targeting different transcriptional factors [16, ...
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Original Article Downregulation of miR-19a promotes the HBV replication via suppressing type I IFN responses in pregnant women
... GAPDH, miR-19a were listed as follows: GAPDH: Forward (F): 5’-CCA TGT TCG TCGTGG GTG TG-3’, Reverse (R): 5’-CCT GCC TTC CTC ACC TGA TG-3’; U6: F: 5’-GCTTCGGCAGCACATATACTAAAAT-3’, R: ...
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miR 19a: an effective regulator of SOCS3 and enhancer of JAK STAT signalling
... of miR-181a in the thymus and miR-223 in the bone marrow being implicated in the differentiation of pluripotent hematopoietic stem cells ...Additionally, miR-155 has been shown to be induced by viral ...
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miR-19a acts as an oncogenic microRNA and is up-regulated in bladder cancer
... Serum miR-19a expression has been reported to correlate with worse prognosis of patients with non- small cell lung cancer ...of miR- 19a in plasma of patients with bladder cancer and found ...
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Original Article Expression pattern and regulation of miR-19a and CCND1 in C3H10T1/2 chondrogenic differentiation
... between miR-19a and CCND1, a cell cycle gene, in chondrogenic differentiation and revealed the possible mechanism of miR-19a engaging in its ...of miR-19a by means of ...
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Original Article MiR-19a is correlated with prognosis and apoptosis of laryngeal squamous cell carcinoma by regulating TIMP-2 expression
... The miR-19a is overexpressed in various cancers and has been causally related to cellular proliferation and ...whether miR-19a plays a role in la- ryngeal squamous cell carcinoma (LSCC), we ...
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Sp1-driven up-regulation of miR-19a decreases RHOB and promotes pancreatic cancer
... of MiR-19a. We found that miR-19a stimulated cell proliferation, migration, invasion in vitro and tumor growth in ...of miR-19a correlated with poor prognosis in ...of ...
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<p>miR-19a Is Involved In Progression And Malignancy Of Anaplastic Thyroid Cancer Cells</p>
... family, miR-15a-16-1, and miR- 143-145 clusters) or as oncogenes (miR-155, miR-21, and miR-17-92 ...44 miR-17-92 cluster, also known as oncomir-1, yields a speci fi c ...
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Original Article MiR-19a targets suppressor of cytokine signaling 1 to modulate the progression of neuropathic pain
... of miR-17-92 cluster located on chromosome 13 [23]. miR-19a is reported to be induced by the interferon-alpha (IFN-α), anti- viral JAK-STAT signaling cytokine ...with miR-19a [25], ...
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<p>MiR-19a Promotes Migration And Invasion By Targeting RHOB In Osteosarcoma</p>
... including miR-223, miR-675, miR-127 and miR-22. 8 – 11 MiR-19a, a member of miR-17-92 cluster that is situated at chromosome ...that miR-19a promoted ...
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<p>Glycine Improves Ischemic Stroke Through miR-19a-3p/AMPK/GSK-3β/HO-1 Pathway</p>
... Trypsin digested the adherent cells and prepared them into cell suspension. Total RNA of cells was extracted by Trizol, and serum RNA was extracted on the basis of the instructions of miRNeasy Serum/Plasma Kit (QIAGEN, ...
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<p>Berberine induces apoptosis in non-small-cell lung cancer cells by upregulating miR-19a targeting tissue factor</p>
... MicroRNAs (miRNAs) are small noncoding RNAs of 18 – 25 nucleotides in length that are expressed in all cells. miRNAs negatively regulate target gene expression via direct binding to 3 ʹ untranslated regions (3 ʹ UTRs)and ...
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Inhibition of miR-19a protects neurons against ischemic stroke through modulating glucose metabolism and neuronal apoptosis
... conserved miR-19a-3p, a crucial component of the miR-17-92 cluster, has been shown to be in- volved in pathogenesis/disease progression in lung cancer [15], gastric cancer [16], breast cancer [17], ...
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Original Article MiR-19a promotes epithelial-mesenchymal transition through PI3K/AKT pathway in gastric cancer
... with miR-19a inhibitor was signifi- cantly lower than that of normal control group (P < ...that miR-19a plays a critical role in AKT activation in ...with miR-19a mimic were ...
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Original Article MicroRNA-19a inhibits nasopharyngeal carcinoma CNE1 cells viability and migration, but induces apoptosis by inhibition of Bcl-2
... of miR-19a on NPC remains ...of miR-19a on NPC cell viability, migration and ...with miR-19a mimic, miR-19a inhibitor, Bcl-2 targeted small interfering RNA (siRNA) ...
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MicroRNA-20b and ERK1/2 pathway independently regulate the expression of tissue factor in hematopoietic and trophoblastic differentiation of human embryonic stem cells
... by miR-19a, miR-20b, and miR-106a, we investigated the potential of these miRNAs to regulate TF expression in G-M cells and trophoblasts differentiated from hESCs and found that miR-20b ...
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Original Article Screening for aberrantly-expressed microRNAs in peripheral blood leukocytes from silicosis patients
... including miR-181, miR-19a, miR-20a, and ...these, miR-181a and miR-19a in peripheral blood white cells were identified as potential biomarkers of sili- cosis, combined ...
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MicroRNA-19a contributes to the epigenetic regulation of tissue factor in diabetes
... specific miR signatures in the healthy vasculature contribute to the control of blood- borne TF expression and alterations in this regulatory network may promote thromboembolic ...endothelial-derived ...
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Networks of MicroRNAs and Genes in Follicular Thyroid Carcinoma
... We should also pay attention to the differentially expressed miRNAs in this network. One miRNA may forms self-adaption relations with several TFs, such as hsa-miR-21 with PTEN and EGFR. Hsa-miR-1 targets ...
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