miR-23a
Original Article Identification of IRF1, PPP2R5E and IL-6R, the target genes of miR-23a in gastric cancer cells
... that miR-23a was effectively silenced by ASO-23a, leading to the upregulation of mRNA of IRF1 and ...Since miR-23a was effectively expressed by pcDNA3/pri-23a, the mRNA ...
8
MiR-23a-depressed autophagy is a participant in PUVA- and UVB-induced premature senescence
... study, miR-23a is a photo-sensitive miRNA that widely participates in the regulation of UV-induced photo- ...of miR-23a could accelerate the senescence of fibroblasts, Ant-23a-treated ...
16
The NF-κB p65/miR-23a-27a-24 cluster is a target for leukemia treatment
... the miR-23a-27a-24 cluster promoter to up-regulate its ...the miR-23a-27a-24 cluster inhibited the expression of the erythroid proteome and contributed to erythroleukemia ...
14
Targeting miR 23a in CD8+ cytotoxic T lymphocytes prevents tumor dependent immunosuppression
... modulate miR-23a expression in effector ...controls miR-23a ...of miR-23a (pri-miR-23a) in cancer cell lines ...and miR-23a expres- sion, we activated ...
17
MiR-23a sensitizes nasopharyngeal carcinoma to irradiation by targeting IL-8/Stat3 pathway
... of miR-23a expression by using miR-23a agomir enhanced NPC radiosensitivity in NPC xenografts, suggesting its considerable potential in radiosensitizing ...of miR-23a agomir, ...
16
Down-regulated miR-23a Contributes to the Metastasis of Cutaneous Melanoma by Promoting Autophagy
... of miR-23a on the invasion and the migration of ...by miR-23a (Fig. 4E-H). To further confirm that miR-23a-ATG12 axis regulated the invasion and migration in an ...
19
Original Article Function and mechanism of miR-23a-3p in the brain gliomas
... one -step method of miRNA manual. TaqMan microRNA reverse transcription kit were used to reverse transcript the total miRNA into cDNA and added MiR-23a-3p or internal refer- ence U6 primer to amplificate. ...
9
NEAT1/miR-23a-3p/KLF3: a novel regulatory axis in melanoma cancer progression
... inhibited miR‑23a‑3p expression through 3′ ‑UTR Bioinformatics analysis based on the online database of starBase was employed for the prediction of NEAT1 ′ s potential target in miRNAs, ...relative ...
10
<p>LncRNA MALAT1 Promotes the Proliferation, Migration, and Invasion of Melanoma Cells by Downregulating miR-23a</p>
... method. miR-23a: forward 5 ʹ - CGC GAT CAC ATT GCC AGG G − 3 ʹ , reserve 5 ʹ - GTG CAG GGT CCG AGG T − 3 ʹ , MALAT1: forward 5 ʹ - GAC GGA GGT TGA GAT GAA GC − 3 ʹ , reserve 5 ʹ -ATT CGG GGC TCT GTA GTC ...
10
The Effects of High Intensity Interval Training on Mir-23a Expression and Related Factors Involved in Muscular Atrophy of Aged Rats
... through Mir-23a signaling pathway ...on Mir-23a expression and Rcan-1 mRNA in the Plantaris muscle of both aged and young ...increased Mir-23a expression as well as Rcan-1 mRNA; ...
7
Original Article MicroRNA-23a regulates cell migration and invasion by target PTEN in gastric cancer
... of miR-23a and low expression of ...of miR-23a on EMT process of GC cells, the inhibitor of miR-23a was transfected into AGS cells and the expression of miR-23a was ...
11
Genetic Variation in Intergenic and Exonic miRNA Sequence and Risk of Multiple Sclerosis in the Isfahan Patients
... of mir-23a rs3745453 have potential to play as a hazard factor for ...of mir 23a, more studies have been conducted on its expression and based on reports of the effect of this miRNA in ...
8
miRNAs Expression and Role of Dicer on Podocyte Injury in PAN Nephrosis Rats
... From our work, we can conclude that characteristic miRNAs of PAN nephrosis were screening. Up-regulated miRNAs (rno-miR-23a, rno-miR-300-3p) may trigger podocyte injury and proteinuria, while ...
8
MicroRNA-23a-3p Inhibits Mucosal Melanoma Growth and Progression through Targeting Adenylate Cyclase 1 and Attenuating cAMP and MAPK Pathways
... including miR-23a-3p was analyzed for stage II and III colon cancer, as a low 16-miRNA level was associated with better 5-year disease-free survival (DFS) in the study cohort ...
16
Role of microRNAs in premature ovarian insufficiency
... (miR-23a, miR-27a, miR-22-3p, miR-146a, miR-196a, miR-290-295, miR-423, and miR-608) related to POI are also examined in order to highlight the issues that ...
7
<p>The role of long non-coding RNA GAS5 in cancers</p>
... Long noncoding RNA GAS5 suppresses tumorigenesis by inhibiting mir-23a expression in non-small cell lung cancer. GAS5 suppresses malignancy of human glioma stem cells via a miR-196a-5p/F[r] ...
9
Bioinformatics-based identification of potential microRNA biomarkers in frequent and non-frequent exacerbators of COPD
... Results: MiR-23a, miR-25, miR-145 and miR-224 were identified to be significantly downregu- lated in COPD patients compared with healthy ...the miR-25 and miR-224 levels ...
12
Neutrophil induced genomic instability impedes resolution of inflammation and wound healing
... of miR-23a and miR-155 ASOs to reduce inflammation and prevent accumulation of DSBs, administration of ASOs to long-term PMN-MP and IEC cultures significantly reduced both cell death and aneuploidy ...
16
Estradiol induces apoptosis via activation of miRNA-23a and p53: implication for gender difference in liver cancer development
... fact, miR-23a mediated XIAP expression has been suggested to have a protective effect and contributes to the sex difference in brain injury in mice ...of miR-23a inhibited the activation of ...
12
MicroRNA-23a regulates epithelial-to-mesenchymal transition in endometrial endometrioid adenocarcinoma by targeting SMAD3
... Human SMAD3 or SMAD5 3 ′ -UTR, containing the putative target site for miR-23a, was amplified from genomic DNA by PCR amplification and inserted into the pmiR-REPORT ™ (RiboBio). The mutation from a site of ...
9