miR-26b
MiR-26a/miR-26b represses tongue squamous cell carcinoma progression by targeting PAK1
... 8]. MiR-26a and miR-26b make up the miR-26 family ...[9]. MiR-26a and miR-26b are commonly dysregulated in various can- cers, as well as involve in multiple biological ...
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Original Article MiR-26b inhibits hepatocellular carcinoma cell proliferation, migration, and invasion by targeting EphA2
... of miR-26b and EphA2 in HCC cell ...of miR-26b in eight HCC cell lines (HepG2, SMMC7721, Huh7, bel-7402, PLC, LM3, 97L and 97H) and human hepatocyte line ...
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MiR-26b/KPNA2 axis inhibits epithelial ovarian carcinoma proliferation and metastasis through downregulating OCT4
... of miR-26b in diverse cancers. In glioma, miR-26b directly reduces EphA2 expression and may act as a tumor suppressor ...of miR-26b can suppress cell apoptosis by targeting ...
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Review Article Downregulation of miR-26b impact on lens epithelial cells in cataract rat
... tumor, miR-26b was confirmed to have negative regulatory function in LECs proliferation and metastasis [14, 22], suggesting that miR-26b may play a role in LECs ...lyzed miR-26b ...
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Original Article The impact of miR-26b on retinal pigment epithelium cells in rhegmatogenous retinal detachment model
... of miR-26b on RPE cell proliferation in RRD MTT assay was adopted to evaluate the impact of miR- 26b on RPE cell proliferation in ...0.05). MiR-26b inhibitor transfection marked- ...
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MiR-26b is down-regulated in carcinoma-associated fibroblasts from ER-positive breast cancers leading to enhanced cell migration and invasion
... include miR-10a [16], miR- 373 [17], and miR-21 [18], which act as regulators of growth, invasion, and ...that miR-21, which is up-regulated in breast cancers and was assumed to be functional ...
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Original Article Reduced expression of miR-26b is associated with poor prognosis of osteosarcoma
... cancer. MiR-26b acts as a tumor suppressor in many types of cancers including osteosarcoma ...of miR-26b is poorly ...serum miR-26b in patients with OS and their respective ...
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Original Article miR-26b suppresses tumor proliferation and metastasis by targeting matrix metalloproteinases 14 in neuroblastoma
... either miR-26b mimics or miRNA control, either pGL3- MMP14 3’-UTR (Wt) or pGL3-MMP14 3’-UTR (Mut), and 2 ng of pRL-TK (Promega) by using Lipofectamine ...
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Original Article miR-26b inhibits total neurite outgrowth, promotes cells apoptosis and downregulates neprilysin in Alzheimer’s disease
... between miR-26b and NEP has not been studied so ...that miR-26b inversely regulated expression of NEP but not EIF2S1 or αTTP in cellular AD ...that miR-26b might be involved in ...
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Twist1-related miR-26b-5p suppresses epithelial-mesenchymal transition, migration and invasion by targeting SMAD1 in hepatocellular carcinoma
... of miR-26b-5p expression occurred, Twist1 expression was obviously upregulated (Figure ...of MIR-26B (Figure 1B) to downregulate miR-26b-5p expression, and SMAD1 has been ...
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<p>miR-26b-5p Inhibits the Proliferation, Migration and Invasion of Human Papillary Thyroid Cancer in a β-Catenin-Dependent Manner</p>
... β -catenin. The RNA level and protein level of β -catenin decreased in the TPC-1-OV and K1-OV cell lines (Figure 5A and B, P<0.01). We next characterized the inter- action between β -catenin and ...
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<p>Restoration of miR-26b expression partially reverses the cisplatin resistance of NSCLC by targeting tafazzin</p>
... with miR-26b was ampli fi ed and subcloned into the pGL3 Luciferase Reporter Vector (Promega, Madison, WI, ...with miR-26b mimic or anti-miR-26b or NCO plus pGL3-wt TAZ or pGL3-mt ...
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Original Article Downregulation of microRNA-26b functions as a potential prognostic marker for osteosarcoma
... of miR-26b expression with clinicopathologic features of patients with osteosarcoma were statistically ...low miR-26b expression level was observed to be closely correlated with dis- tant ...
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MicroRNA-26b inhibits tumor metastasis by targeting the KPNA2/c-jun pathway in human gastric cancer
... by miR-26b (Figure S3B and ...of miR-26b, the 3′UTR and its corresponding mutant counterparts were fused to the pMIR-REPORT Luciferase ...that miR-26b downregulates KPNA2 ...
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-induced injury on cardiac myocytes via its target gene HGF
... expected, miR-26b expression changed ...of miR-26b in ROS-mediated H9c2 cells apopto- sis, miR-26b expression was modulated via transfection of miR-26b inhibitor ...
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Changes in microRNA expression profile in hippocampus during the acquisition and extinction of cocaine-induced conditioned place preference in rats
... and miR-26b is reported to negatively regulate brain-derived neurotrophic factor (BDNF) expression at post-transcriptional level ...as miR-181a, miR-124 and let-7b [7,8]. MiR-212 in the ...
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MicroRNA-26b attenuates monocrotaline-induced pulmonary vascular remodeling via targeting connective tissue growth factor (CTGF) and cyclin D1 (CCND1)
... and miR-26b (No difference was identified regarding the observed parameters such as cell proliferation, vascular thickness, the expression of CTGF, CCND1,α-SM actin, or cell cycle progression between the ...
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Original Article Overexpression of microRNA-26b attenuates angiotensin II-induced cardiac hypertrophy through inhibition of autophagic responses
... The miR-26b stem-loop RT primer used was: 5’-GTCGTATCCAGTGCAGGGTCCGAGGTATT- CGCACTGGATACGACACCTAT-3’; miR-26b 5’-TTC- AAGTAATTCAGG-3’ (sense), and 5’-GTGCAG- GGTCCGAGGT-3’ (antisense); while ...
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MicroRNA-26b inhibits cell proliferation and cytokine secretion in human RASF cells via the Wnt/GSK-3β/β-catenin pathway
... that miR-26a, which has the same core sequence with miR-26b, is indeed a functional gene product and is capable of binding to GSK-3 β and directly regulating its expression ...of ...
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Myc Enforces Overexpression of EZH2 in Early Prostatic Neoplasia via Transcriptional and Post-transcriptional Mechanisms
... in miR-26a and miR-26b, known regulators of EZH2 in some non-prostate cell types, albeit not in ...regulates miR-26a and miR-26b via direct binding to their parental Pol II gene ...
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