miR-31
Original Article Overexpression of miR-31-5p inhibits human chordoma cells proliferation and invasion by targeting the oncogene c-Met through suppression of AKT/PI3K signaling pathway
... that miR- 31-5p could regulate c-Met by targeting directly as detected by dual-luciferase ...of miR-31-5p mimics and found c-Met reverse the effect of miR-31-5p on cell ...
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Original Article LncRNA linc01116 prometes glioma cell migration and invasion by modulation of radixin targeted by miR-31
... and miR-31 expression was measured in 135 cases of human glioma tissues and normal brain tissues using Real-time quantitative PCR ...and miR-31, or miR-31 and ...of ...
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Colonic epithelial miR-31 associates with the development of Crohn’s phenotypes
... colonic miR-31 expression as central to clinically relevant molecular subtypes found in inde- pendent cohorts of adult and treatment-naive pediatric ...of miR-31 in medically refractory adult ...
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The Function of miR 31 Expression in Differentiation of Neural Stem Cells
... of miR-31 related to cancer. Compared with normal tissues, miR-31 up-regulated at head and neck cancer (Wong et al, 2008) [7], colorectal cancer (motoyama et al, 2009; wang CJ et al, 2009) [8] ...
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miR 31 controls osteoclast formation and bone resorption by targeting RhoA
... of miR-21, and its silencing suppresses osteoclastogenesis [6]. miR-155 deficiency suppressed osteoclastogenesis and bone destruction in a murine arthritis model ...[8]. miR-223 suppressed expression ...
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Original Article miR-31 inhibits cell proliferation and invasion through targeting ROCK1 in prostate cancer
... of miR-31 have been confirmed in previous studies, including LATS2, PPP2R2A, and tyro- sine kinase MET [11, ...in miR-31-overexpressed PCa ...with miR-31 mimics, as indicated by ...
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Downregulated miR-31 level associates with poor prognosis of gastric cancer and its restoration suppresses tumor cell malignant phenotypes by inhibiting E2F2
... to miR-31 and named as mt ...with miR-31 mimic or miR-ctrl) were transiently transfected into gastric cancer SGC-7901 and MGC-803 cells using Lipofectamine 2000 reagent ...
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Original Article Clinical significance of serum miR-31 as a predictive biomarker for lung adenocarcinoma
... serum miR-31 in LUAD was largely ...serum miR-31 levels and prognosis of LUAD. We first analyzed miR-31 as a predictor of overall survival in the LUAD patients from The Can- cer ...
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MicroRNA expression profiling identifies miR-31-5p/3p as associated with time to progression in wild-type RAS metastatic colorectal cancer treated with cetuximab
... Because miR-31-5p is the leading strand of miR-31, we hypothesize, that miR-31- 5p is responsible for major effects caused by miR-31 and miR-31-3p ...
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Polymorphism in miR-31 and miR-584 binding site in the angiotensinogen gene differentially influences body fat distribution in both sexes
... recently, miR-31 and miR-584 were found to influence the expression of angiotensinogen, with an important effect of ?11525 C/A (rs7079) genotype: the downregulation of AGT gene expression by these ...
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miR-31 is distinctively overexpressed in primary male extra mammary Paget’s disease
... miRNAs, miR-375, miR-10b, miR-31( miR-31-5p) and miR-31* (the complementary miRNA of miR-31, miR-31-3p) were differentially expressed ...
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miR-31 affects colorectal cancer cells by inhibiting autophagy in cancer-associated fibroblasts
... genes. miR-31 plays an important role in the development of colorectal ...of miR-31 promotes the incidence of colorectal cancer [9– 11], while down-regulation of miR-31, ...
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P18/Stathmin1 is regulated by miR-31 in ovarian cancer in response to taxane.
... To generate 3’-UTR luciferase reporter, partial sequence of the 3’-UTR from stmn1 were cloned into the downstream of the firefly luciferase gene in pGL4.11 control vector (Promega, Madison, WI, USA). The 3’- UTR of stmn1 ...
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Original Article MiR-31 is a potential biomarker for diagnosis of head and neck squamous cell carcinoma
... tissue miR-31 expression group had lon- ger overall survival (OS) ...serum miR- 31 expression group had shorter OS ...um miR-31 expression and clinicopathological ...sue ...
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MiR-31 regulates the cisplatin resistance by targeting Src in gallbladder cancer
... that miR-31 may directly target the 3'-UTR of the Src mRNA based on a perfect match of binding sites detected by the Target Scan and miRBase ...the miR-31 mimics. Moreover, an inverse ...
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<p>Long Non-Coding RNA TUG1 Promotes Cell Proliferation and Inhibits Cell Apoptosis, Autophagy in Clear Cell Renal Cell Carcinoma via MiR-31-5p/FLOT1 Axis</p>
... Moreover, miR-31-5p was validated as a direct target of TUG1, and microRNA miR-31-5p inhibitor mitigated the effects of TUG1 knockdown on ccRCC ...with miR-31-5p. FLOT1 ...
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MicroRNA profiling in sera of patients with type 2 diabetes mellitus reveals an upregulation of miR 31 expression in subjects with microvascular complications
... MicroRNA miR-31 (Figure 2 indicated by the arrow) was located far from the ideal correlation fitting line both in T2D without complica- tions vs T2D with macrovascular (Figure 2(a)) or with microvascular ...
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BAP1 suppresses lung cancer progression and is inhibited by miR-31
... validated miR-31 as a direct regulator of BAP1. Moreover, we showed that miR-31 promoted proliferation and suppressed apoptosis in lung cancer cells and accelerated the development of tumor ...
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Original Article LincRNA-SLC20A1 (SLC20A1) promotes extracellular matrix degradation in nucleus pulposus cells in human intervertebral disc degeneration by targeting the miR-31-5p/MMP3 axis
... SLC20A1/ miR-31-5p/MMP pathway in ECM degradation in NP cells from patients with ...the miR-31-5p/MMP ...between miR-31-5p and either SLC20A1 or ...
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Tumor suppression by miR-31 in esophageal carcinoma is p21-dependent
... RNAs, miR-31, but its role is complicated because it can act as either a tumor suppressor or an oncogene: while it inhibits cell proliferation of serious ovarian carcinomas [11] and cell metastasis in ...
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