miR-93
<p>LncRNA PLAC 2 Is Downregulated in Osteosarcoma and Regulates Cancer Cell Proliferation Through miR-93</p>
... downregulated miR-93 in MG-63 and U2OS ...with miR-93 mimic or PLAC 2 expression vector to analyze the interactions between PLAC 2 and ...and miR-93 was con fi rmed at 24 h ...
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Repression of the miR-93-enhanced sensitivity of bladder carcinoma to chemotherapy involves the regulation of LASS2
... of miR-93 were observed in the cisplatin-resistant BC cell line RT4, compared to the cell line ...of miR-93 in chemo-sensitivity was demonstrated both in cell culture and mouse tumor xenograft ...
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Expression Profiles of miR-93 and miR-330 in Iranian Patients with Chronic Lymphocytic Leukemia
... that miR-93 and miR-330 as a miRNAs are related to major molecular genetic alterations in acute myeloid leukemia ...of miR-93 in CLL. Expression of miR-93 was ...
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miR-93/miR-106b/miR-375-CIC-CRABP1: a novel regulatory axis in prostate cancer progression
... that miR-93, miR- 106b, and miR-375 cooperatively regulate CIC ...that miR-93 and miR-106b may not function redundantly to regulate CIC levels, although they share the ...
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MiR-93 regulates vascular smooth muscle cell proliferation, and neointimal formation through targeting Mfn2
... of miR-93 in regulating VSMC proliferation, we screened the predicted target candidates of miR-93 in silico to identify genes related to cell cycle ...the miR-93 inhibitor was ...
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miR-93-5p enhance lacrimal gland adenoid cystic carcinoma cell tumorigenesis by targeting BRMS1L
... how miR-93-5p affects LACC cell EMT and tumorigenesis, bioinformatic online database (Tar- getScan) was used to predict putative target of miR- ...with miR-93-5p were predicted ...
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Original Article DNA methylation of miR-93 : an important event in acquiring drug resistance in breast cancer cells
... in miR-93 overexpressed sensitive breast cancer cells, proliferation was markedly increased, while apoptosis was markedly ...These miR-93-induced drug resistance trends can also be noticed in ...
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miR-93 Promotes Cell Proliferation in Gliomas through Activation of PI3K/Akt Signaling Pathway
... of miR-93 was markedly upregulated in glioma cell lines and clinical glioma ...that miR-93 levels significantly correlated with clinicopathologic grade and overall survival in ...
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Overexpressing lncRNA <em>SNHG16</em> inhibited HCC proliferation and chemoresistance by functionally sponging hsa-miR-93
... Patients and methods: SNHG16 expressions were tested by quantitative real-time PCR (qRT-PCR) in HCC cell lines, as well as 43 pairs of HCC tissues and pair-matched healthy hepatic tissues. It was overexpressed in Hep3B ...
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Original Article Downregulation of miR-93 elevates Nrf2 expression and alleviates reactive oxygen species and cell apoptosis in diabetic retinopathy
... between miR-93 and 3’-UTR of Nrf2 ...of miR-93 and Nrf2/ARE signal pathway proteins were examined to investigate the roles of miR-93 in ...of miR-93, Nrf2, heme ...
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Up-Regulation of miR-21, miR-25, miR-93, and miR-106b in Gastric Cancer
... microRNAs, also known as miRNAs, are small, endogenous non-coding RNA molecules consisting of approximately 22 nucleotides. miRNAs, found in plants, animals, and some viruses, control gene expression through RNA ...
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MicroRNA-93-5p may participate in the formation of morphine tolerance in bone cancer pain mouse model by targeting Smad5
... cancer, miR-93 may target LATS2 to enhance metastasis or downregulate NEDD4L to promote TGF-β-induced epithelial-to-mesenchymal transition, an important mechanism for cancer metastasis [14, ...
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Investigating the mechanism of hepatocellular carcinoma progression by constructing genetic and epigenetic networks using NGS data identification and big database mining method
... let-7a, mir-148a, and mir-93) that were differentially methylated or dysregulated, causing the perturbation of the MAPK and ErbB pathways, resulting in the aberrant regulation of MYC on DUSP1, EIF4E, ...
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microRNA-93 promotes cell proliferation via targeting of PTEN in Osteosarcoma cells
... Since the introduction of anti-miR-93 significantly inhib- ited cell proliferation of OS Saos cell lines, we hypo- thesized that anti-miR-93 might reduce the cell cycle progression and⁄or ...
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MicroRNA-93 activates c-Met/PI3K/Akt pathway activity in hepatocellular carcinoma by directly inhibiting PTEN and CDKN1A
... identified miR-93 as a novel target associated with ...verified miR-93 expression levels in advanced HCC tumors (n=47) by a direct PCR assay and found that elevated miR-93 ...
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Attenuation of TGFBR2 expression and tumour progression in prostate cancer involve diverse hypoxia-regulated pathways
... regulators, miR- NAs can negatively regulate gene expression by binding directly to the 3’-UTR of corresponding target mRNAs in a sequence-specific manner, forming RISC and inducing mRNA degradation or protein ...
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MicroRNA-93 inhibits ischemia-reperfusion induced cardiomyocyte apoptosis by targeting PTEN
... PI3K/Akt is an intracellular signaling pathway, which also involve in the cardioprotection [18]. PI3K, when activated, has the ability to phosphorylate PIP2 into the secondary messenger PIP3 and lead the activation of ...
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Original Article Up-regulation of MicroRNA-93 predicates advanced clinicopathological features and serves as an unfavorable risk factor for survival of patients with non-small cell lung cancer
... between miR-93 levels and clinic-pathological features of 104 patients with NSCLC and found that high expression of miR-93 was significantly cor- related with advanced clinical stage and posi- ...
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miR 105/93 3p promotes chemoresistance and circulating miR 105/93 3p acts as a diagnostic biomarker for triple negative breast cancer
... tween miR-105 (or miR-93-3p) and ...either miR-105 or miR-93-3p with Ago2, SFRP1 mRNA was found to bind both miR-105 and miR-93-3p ...overexpression ...
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MicroRNA-93-5p promotes epithelial-mesenchymal transition in gastric cancer by repressing tumor suppressor AHNAK expression
... that miR-93-5p is closely associated with GC progression, and overexpression of miR-93-5p leads to distant metas- tasis and poor survival in patients with GC ...of miR-93-5p ...
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