MiRNAs and development
A framework for understanding the roles of miRNAs in animal development
... way miRNAs contribute to development? Eric Davidson pioneered the view that development can be explained by the complete map of interactions between regulatory genes that eventually define when and ...
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Applications of miRNAs in cardiac development, disease progression and regeneration
... the development of congenital heart ...progenitor miRNAs and adult cardiac-specific miRNAs is a potential break- through to generate proliferative progenitor niches via miRNA ...of miRNAs and ...
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miREC: a database of miRNAs involved in the development of endometrial cancer
... of miRNAs in the development of ...and miRNAs potentially involved in endometrial cancer ...and miRNAs from different starting points, such as differential expression and genomic loci (based ...
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Exosomal miRNAs in hepatocellular carcinoma development and clinical responses
... nucleotides. miRNAs bind to the 3′UTR of pre- mRNAs during the process of post-transcriptional regula- tion and guide degradation of target ...rapid development of next-generation sequencing, miRNAs ...
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Exosomal and non-exosomal circulatory miRNAs in bovine follicular fluid : potential role of exosomal miRNAs in oocyte development
... miRNAs and the 3’UTR of mRNAs of the potential target genes(Wang et ...follicular development, a total of seven target genes (ITGA3, MAP3K1, SOCS4, BRMS1L, ZNFX1, CD44 and VEGFA) were selected for ...
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miRNAs cooperate in apoptosis regulation during C. elegans development
... family miRNAs critically contribute to the precise control of programmed cell death during ...elegans development We demonstrate that miR-35 and miR-58 family miRNAs fine-tune EGL-1 activity and ...
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Identification of miRNAs during mouse postnatal ovarian development and superovulation
... of miRNAs revolutionized the unantici- pated regulation of transcriptome and ...of miRNAs as this technique is considered an efficient way for miRNA discovery and is widely used to produce small RNA ...
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miRNAs affect the development of hepatocellular carcinoma via dysregulation of their biogenesis and expression
... tumor-specific miRNAs are widely deregulated or upregulated in HCC and closely associated with the occurrence and development of various cancers, including ...that miRNAs have critical roles in HCC ...
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High-Throughput Sequencing Reveals miRNAs Affecting Follicle Development in Chicken
... sequenced miRNAs of the hair follicle derived from the 13 day-old chicken (Gallus gallus) embryos in which from Kirin chicken and Huaixiang chicken that feathers having morphogenesis with significantly different ...
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The influence of miRNAs on variation of gene expression during T-cell development
... For miRNAs to have a role in regulating biological noise during development, they must form part of the regulatory networks which control T-cell develop- ment and ...the miRNAs which target Cd69 ...
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Investigation of miRNAs enrichment and degradation in bovine granulosa cells during follicular development
... Follicular development is the outcome of multifarious hormonal and biochemical interactions that could be triggered or deactivated within the follicular environment in a spatiotemporal ...follicular ...
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Sperm borne miRNAs and endo siRNAs are important for fertilization and preimplantation embryonic development
... in miRNAs and/or endo-siRNAs, thus providing a unique opportunity for testing whether normal sperm ( paternal) or oocyte (maternal) miRNA and endo- siRNA contents are required for fertilization and preimplantation ...
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missing LINKS: mirnas and plant development Christine Hunter and R Scott Poethig
... LINKS: miRNAs and plant development Christine Hunter and R Scott Poethig The discovery of hundreds of plant micro RNAs (miRNAs) has triggered much speculation about their potential roles in plant ...
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Profiling microRNAs through development of the parasitic nematode Haemonchus identifies nematode-specific miRNAs that suppress larval development
... elegans development to reproductive stage requires activation of the DAF-2 insulin receptor and daf-2 loss of function (lf) mutants are dauer constitutive (daf-c) at restrictive temperature 33 ...these ...
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Next generation sequencing for profiling expression of miRNAs: technical progress and applications in drug development
... ABSTRACT miRNAs are non-coding RNAs that play a regulatory role in expression of genes and are associated with ...of miRNAs can help in understanding the mechani- sms of human diseases and discovering new ...
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Lin28 proteins promote expression of 17∼92 family miRNAs during amphibian development
... The paralogous mir;17~92 and mir;106~363 clusters each code for six miRNAs, which have been highly conserved during vertebrate evolution. The mir;17~92 cluster, in particular, has attracted a great deal of ...
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The Tumor Cytosol miRNAs, Fluid miRNAs, and Exosome miRNAs in Lung Cancer.
... cancer. miRNAs are single-stranded, small non-coding RNAs that regulate gene expression and show tissue-specific ...Moreover, miRNAs are stable in serum and other clinically convenient and available tissue ...
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Mirnas and Cancer
... The development of animal model that mimics human diseases is the way that is usually employed to address the genetic influence on human ...the development of CLL-like ...these miRNAs was associated ...
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The role of miRNAs in stroke
... 1.16 miRNAs in Cardiovascular Disease Following the initial discovery and description of miRNA function there has been increased interest in the role that these molecules play in cardiovascular ...of miRNAs ...
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MiRNAs as novel adipokines : obesity-related circulating MiRNAs influence chemosensitivity in cancer patients
... the development of some cancers, and less likely to achieve event-free survival following ...circulating miRNAs which are reproducibly altered in obesity, and secondly to identify mechanisms by which these ...
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