Mitochondrial markers
Mitochondrial markers predict survival and progression in non small cell lung cancer (NSCLC) patients : use as companion diagnostics
... enhanced mitochondrial function, we show here that mitochondrial markers effectively predict poor overall survival in lung cancer patients, with negative surgical ...these mitochondrial ...
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Identification of sympatric cryptic species of Aedes albopictus subgroup in Vietnam: new perspectives in phylosymbiosis of insect vector
... of mitochondrial markers Mosquito DNA extraction was performed following our previous optimized protocol for individual whole mosquitoes ...the mitochondrial nico- tine adenine dinucleotide ...
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Dispersal and group formation dynamics in a rare and endangered temperate forest bat (Nyctalus lasiopterus, Chiroptera: Vespertilionidae)
... Colonization of new areas and the formation of new colonies are rare events that have seldom been described in bats, and on only one occasion has colonization been stud- ied in detail from a genetic perspective ...
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Dispersal and group formation dynamics in a rare and endangered temperate forest bat (Nyctalus lasiopterus, Chiroptera: Vespertilionidae)
... Using nuclear and mitochondrial markers, we studied patterns of genetic diversity 31and differentiation among and within breeding colonies of giant noctule bats Nyctalus 32lasiopterus, t[r] ...
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Genetic diversity of mitochondrial dna genes in oral cavity cancers in senegal
... Oral cavity cancers (OCC) represent approximately 25 to 30% of cancers of the upper aero digestive tract (UAT) i.e. head and neck carcinomas. OCC is the 4 th most common cancer in men and the14 th most frequent among ...
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Population genetic structure of Schistosoma bovis in Cameroon
... the mitochondrial (cox1) and nuclear markers (microsatellites) indicated that most of the genetic vari- ation observed among parasites is observed within and not between sampled ...comparable markers ...
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Molecular characterization and classification of Trypanosoma spp Venezuelan isolates based on microsatellite markers and kinetoplast maxicircle genes
... the mitochondrial membrane potential and several mutations that affect its function have been described in diskinetoplastic trypanosomes ...[71–73]. Mitochondrial genes have been proposed as excellent ...
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GENETIC RELATIONSHIP BETWEEN ROSELLE (HIBISCUS SABDARIFFA L.) AND KENAF (HIBISCUS CANNABINUS L.) ACCESSIONS THROUGH OPTIMIZATION OF PCR BASED RAPD METHOD
... The PCR based RAPD analysis was used to study genetic relationship among roselle and kenaf accessions. Extraction of genomic DNA samples of nine roselle (Hibiscus sabdariffa L.) and seven kenaf (Hibiscus cannabinus L.) ...
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Mitochondrial biomarkers predict tumor progression and poor overall survival in gastric cancers : companion diagnostics for personalized medicine
... these mitochondrial markers could also be employed as companion diagnostics for novel therapies targeting either mitochondrial protein translation or cellular respiration, to select the high-risk ...
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An acid transporting enzyme in human gastric mucosa
... Isolation of a microsomal fraction from human gastric mucosa followed by density gradient centrifugation yielded a vesicular membrane preparation free of mitochondrial markers, containing a K+-activated, ...
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Effect of Estrogen on Mitochondrial Function and Intracellular Stress Markers in Rat Liver and Kidney following Trauma-Hemorrhagic Shock and Prolonged Hypotension
... of mitochondrial func- tion in liver revealed that T-H increased the maximum electron transfer capacity of the mitochondrial respiratory chain and the sensitivity of mitochondrial succinate-dependent ...
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Evolution of Nuclear Integrations of the Mitochondrial Genome in Great Apes and their Potential as Molecular Markers
... Alternatively, isolating numts is desired when the interest is for example estimating numt prevalence, numt mechanisms of insertion, sequence divergence from mtDNA or testing the distribution of polymorphic insertions in ...
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Mitochondrial stress and activation of PI3K and Akt survival pathway in bladder ischemia
... Purpose: Detrusor overactivity contributes to bothersome constellation of lower urinary tract symptoms (LUTS) in men and women as they age. However, the underlying mechanisms of non- obstructive detrusor overactivity and ...
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... (5, 6) have suggested that NAPQI exerts a cytotoxic effect through its covalent binding to cytosolic or microsomal proteins and membrane components, inducing oxidative stress in cells, inhibition of mitochondrial ...
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Molecular species identification of Central European ground beetles (Coleoptera: Carabidae) using nuclear rDNA expansion segments and DNA barcodes
... nuclear markers and the COI sequence divergence (K2P distances: 0 to ...molecular markers in this ...different markers should be tested to understand the population structure of this species complex ...
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Chemotherapy-related cachexia is associated with mitochondrial depletion and the activation of ERK1/2 and p38 MAPKs
... tetroxide (OsO4) in 0.1 M SC buffer for 60 minutes. After post-fixation, samples were rinsed three times in 0.1 M SC buffer and dehydrated through a graded series of alcohol. The specimens were then placed in pure ...
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Strong genetic differentiation among east Atlantic populations of the sword razor shell (Ensis siliqua) assessed with mtDNA and RAPD markers
... employing mitochondrial and RAPD markers suggest the existence of a strong popu- lation diVerentiation between Irish and Iberian localities (except Aveiro) and absence of gene ...
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Geographical genetic structure of Schistosoma japonicum revealed by analysis of mitochondrial DNA and microsatellite markers
... random amplified polymorphism DNA (RAPD) analysis, and found genetic variability among Chinese S. japonicum populations. Subsequently, a set of high-resolution micro- satellite markers was used to investigate the ...
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Geographical genetic structure of Schistosoma japonicum revealed by analysis of mitochondrial DNA and microsatellite markers
... At the 10 microsatellite loci, 317 unique MLGs were de- tected from 353 individuals (individuals with missing data were excluded: Table 1), and no MLG was shared among populations. According to the PCoA, the MLGs of 262 ...
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Azelnidipine prevents cardiac dysfunction in streptozotocin-diabetic rats by reducing intracellular calcium accumulation, oxidative stress and apoptosis
... Increased oxidative stress is believed to be an initial and important step in the development of cardiac dysfunction and cardiomyopathy. NADPH oxidase and mitochondria are considered to be important sources of ROS ...
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