Mixed connective tissue disease
Mixed connective tissue disease: state of the art on clinical practice guidelines
... Mixed connective tissue disease (MCTD) is a complex overlap disease with features of different autoimmune connective tissue diseases (CTDs) namely systemic sclerosis, ...
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Mixed connective tissue disease complicated by heart failure in Ile-Ife, Nigeria: management challenges in a resource-limited economy
... nated an overlap syndrome of SLE, generalized scleroderma, and PM, which they considered to be a novel class of a “rheumatic disease syndrome dissimilar from the overlap syn- dromes” and termed it “mixed ...
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Endothelial cell markers reflecting endothelial cell dysfunction in patients with mixed connective tissue disease
... cardiovascular disease; CS: corticosteroids; dsDNA: double-single DNA; ELISA: enzyme-linked immunosorbent assay; ESR: erythrocyte sedimentation rate; FMD: flow-mediated dilation; HDL-C: high-density ...
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Purification and Biochemical Characterization of Nuclear Ribonucleoprotein Antigen using Purified Antibody from Serum of a Patient with Mixed Connective Tissue Disease
... We have achieved a high degree of purification of nuclear ribonucleoprotein antigen from calf thymus nuclear extract through antibody affinity chromatography. Antibody to nuclear ribonucleoprotein was purified from the ...
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First report of cardiac tamponade in pediatric onset mixed connective tissue disease
... Pediatric-onset Mixed Connective Tissue Disease (MCTD) is a rare condition that has differentiated itself from adult-onset MCTD in the last 40 ...two connective tissue ...
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Mixed connective tissue disease presenting as atrial fibrillation, fever, lymphadenopathy, and pericardial effusion
... Introduction: Mixed connective tissue disease (MctD) is a poorly understood rheumatologic condition that presents with clinical symptoms related to the underlying presence of distinct ...
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Depression and anxiety and their association with healthcare utilization in pediatric lupus and mixed connective tissue disease patients: a cross-sectional study
... of mixed connective tissue disease (MCTD) are chronic autoimmune diseases characterized by systemic multi-organ inflammation, with significant morbidity and mortality occurring due to the ...
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Associations between circulating endostatin levels and vascular organ damage in systemic sclerosis and mixed connective tissue disease: an observational study
... other connective tis- sue diseases (CTDs) and is particularly evident in mixed connective tissue disease (MCTD), a chronic immune- mediated disease associated with anti-U1-RNP ...
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Improved Serological Differentiation between Systemic Lupus Erythematosus and Mixed Connective Tissue Disease by Use of an SmD3 Peptide-Based Immunoassay
... Autoantibodies to the Sm antigens are specifically found in 5 to 30% of patients with systemic lupus erythematosus (SLE) depending on the detection system and the patient group. Several immunoassays designed for research ...
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Circulating 20S Proteasome Levels in Patients with Mixed Connective Tissue Disease and Systemic Lupus Erythematosus
... parallel disease activity ...ical disease indices and serologic parameters in patients with SLE is unknown, and c20S have not been studied in mixed connective tissue disease ...
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Mixed Connective Tissue Disease in Children and Adolescents
... A review of 234 reported patients with mixed connective tissue disease, including 50 pediatric patients, suggests a higher prevalence of renal and cardiac disease in affected children an[r] ...
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Esophageal Motor Abnormalities in Children and Adolescents With Scleroderma and Mixed Connective Tissue Disease
... nective tissue disease, esophageal manometry was per- formed on seven patients with progressive systemic sclerosis, four patients with mixed connective tissue.. disease, and two patients[r] ...
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Autoantibodies specific for apoptotic U1 70K are superior serological markers for mixed connective tissue disease
... autoantigens. Mixed connective tissue dis- ease (MCTD) is a relatively rare systemic autoimmune dis- ease and includes a group of patients with overlapping clinical symptoms of systemic lupus ...
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Disease evolution in mixed connective tissue disease: results from a long term nationwide prospective cohort study
... Defining a clinical entity based on auto-antibody speci- ficity was viewed as controversial in 1972, but the con- tinuing discoveries of relevant auto-antibody analyses for diagnostic and risk classification purposes ...
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Barriers and facilitators for mental healthcare in pediatric lupus and mixed connective tissue disease: a qualitative study of youth and parent perspectives
... the disease course [38], as well as the high occurrence of co-morbid mental disorders, may facilitate youth and parent reporting of mental ...chronic disease in subspecialty ...
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Thrombotic Thrombocytopenic Purpura Associated with Mixed Connective Tissue Disease: A Case Report
... TTP associated with mixed connected tissue disease is rare and has only been described in nine patients (Table 2) [13–21]. Most of these cases were women (8 : 1) with the median age of 40 years. The ...
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Antimyenteric neuronal antibodies in scleroderma
... 10 mixed connective tissue disease patients' sera stained myenteric plexus neurons, when positive sera were absorbed with calf thymus extract to remove antinuclear antibody, 15 scleroderma ...
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Association of autoantibodies to different nuclear antigens with clinical patterns of rheumatic disease and responsiveness to therapy
... Using a hemagglutination test which can detect antibodies to (a) native and denatured deoxyribonucleic acid (DNA) and (b) an extractable nuclear antigen (ENA), a comparative study of patterns of autoantibody formation ...
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Antibodies to cellular antigens in Sjögren's syndrome
... l Abbreviations used in this paper: ANA, antinuclear antibodies; DLE, discoid lupus erythematosus; IEP, immunoelectrophoresis; MCTD, mixed connective tissue disease; 2-ME, 2-mercaptoetha[r] ...
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Predictors of mortality in connective tissue disease associated pulmonary arterial hypertension: a cohort study
... CTD: connective tissue disease; CTD-PAH: connective tissue disease- associated pulmonary arterial hypertension; DLCO: diffusing capacity of carbon monoxide; DVT: deep vein ...
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