MMP-2. Matrix metalloproteinases
Evaluation of matrix metalloproteinases (MMP)-2 and MMP-9 activity in serum and biochemical and hematological parameters in spontaneous canine cutaneous tumors before and after surgical treatment
... some modifications. Fifteen µL of each serum sample was diluted in sample buffer 4X (10 mL of 250 mM Tris-HCl, pH 6.8; 40.00% glycerol; 8.00% SDS; and 0.01% bromophenol blue) (1:1 ratio). An amount of 15 µL diluted serum ...
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Study of Correlation between Prostate Specific Antigen and Matrix Metalloproteinase-2 Activity in Benign and Malignant Prostate Hyperplasia
... extracellular matrix (ECM), followed by invasion, a critical early step in the metastatic ...of matrix-degrading serine proteases and matrix metalloproteinases (MMP) with invasion, ...
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Functional polymorphisms in matrix metalloproteinases -1, -3, -9 and -12 in relation to cervical artery dissection
... in 2% to 3% of ...extracellular matrix (ECM) of skin biopsies even in patients without known connective tissue ...[10]. Matrix metalloproteinases (MMP) are interesting candidate genes ...
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Matrix metalloproteinases and epileptogenesis
... ding MMP-2, MMP-9, and MMP-13 was demonstrated in neuronal nuclei of brains at an early stage of ischemic stroke and reperfusion injury ...a matrix that resembles the ECM and provides ...
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Matrix metalloproteinases in the mouse retina: a comparative study of expression patterns and MMP antibodies
... in MMP expression and activity levels, rather than determining the spatial localization and function of these ...of MMP expression/activ- ity, extensive regulation of MMPs at transcriptional, translational ...
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Role of matrix metalloproteinases (MMPs) and MMP inhibitors on intracranial aneurysms: a review article
... membrane-type matrix metallopro- teinase-1(MT1-MMP), and matrix metalloproteinase-2 (MMP-2) in aneurysmal wall is more than what we ob- serve in normal cerebral ...arteries. ...
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<p>MMP-2, MMP-9, TIMP-1, and TIMP-2 in the Peripheral Blood of Patients with Differentiated Thyroid Carcinoma</p>
... R. Metalloproteinases as common effectors of in fl ammation and extracellular matrix breakdown in breast ...nases 2 and 9 (MMP-2 and MMP-9) during human colorectal tumor- ...al. ...
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Immunohistochemical expression of Matrix Metalloproteinase-2 (MMP-2) in inguinal hernia
... extracellular matrix components predominantly collagen is controlled by an equilibrium between matrix metalloproteinases and their inhibitors (43) ....Matrix metalloproteinases (MMPs) ...
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Matrix Metalloproteinases-2, -8, and -9 and TIMP-2 in Tracheal Aspirates From Preterm Infants With Respiratory Distress
... derived MMP-8 spe- cies are expressed in the lungs of preterm infants suffering from respiratory ...latent MMP-8 levels indicates that mes- enchymal cell– derived MMP-8 may play a role in the ...
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The role of synovial macrophages and macrophage produced cytokines in driving aggrecanases, matrix metalloproteinases, and other destructive and inflammatory responses in osteoarthritis
... ADAMTS metalloproteinases in the OA synovial cell ...PCR. MMP-1 was significantly (p < ...of MMP- 1 (Figures 5 and 6). With regard to MMP-13, the effect of neu- tralising each cytokine on ...
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Elevated serum concentrations of metalloproteinases (MMP-2, MMP-9) and their inhibitors (TIMP-1, TIMP-2) in patients with Graves’ orbitopathy
... MMPs, MMP-2 and MMP-9 are very important for collagen degra- ...extracellular matrix, including natural tissue inhibitors of metalloproteinase ...of MMP-9, andTIMP-2,-3, and -4 ...
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Antioxidative and Anti-Aging Effects of Pinus Rigida Mill. Ethyl Acetate Extract on the Human Dermal Fibroblast Cell Line CCD-986sk Damaged by Ultraviolet B Radiation
... of MMP-1, -2, and -3 in CCD-986sk cells stimulated with UVB among the matrix metalloproteinases found in the dermal layers, which cause collagen ...Keywords: Matrix ...
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Matrix metalloproteinases-9 (mmp-9) gene polymorphisms in patients with or without family history of myocardial infarction
... serum MMP-9 levels in both the subject groups for present study. Serum MMP-9 levels was not significantly differs ...serum MMP-9 levels in both the study groups for MMP-9 R279Q (p= ...and ...
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Original Article Serum levels of matrix metalloproteinase-2 and matrix metalloproteinase-9 have clinical significance for the evaluation of the prognosis of patients with ruptured intracranial aneurysms after interventional therapy
... to matrix metalloproteinases (MMPs), such as MMP-2 and MMP-9 ...of MMP-2 and MMP-9 in peripheral blood can be of impor- tance in the prediction of prognosis of IA ...
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Matrix metalloproteinases and their tissue inhibitors after selective laser trabeculoplasty in pseudoexfoliative secondary glaucoma
... the MMP-2 and TIMP-2 values in the aqueous samples of 15 patients with pseudoexfoliative glaucoma (PEXG-SLT group) (8 males and 7 females aged from 58 to 66, mean ...
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Markers of increased cardiovascular risk in patients with chronic kidney disease
... of matrix metalloproteinases and their inhibitors revealed that the level of MMP-2 was much higher in patients with chronic kidney disease in comparison to the control group (p = ...of ...
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Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques
... extracellular matrix (ECM) metabolism may contribute to vascular remodeling during the development and complication of human atherosclerotic ...of matrix metalloproteinases (MMPs), a family of ...
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Active synovial matrix metalloproteinase 2 is associated with radiographic erosions in patients with early synovitis
... Several metalloproteinases that are capable of the proteolytic degradation of extracel- lular matrix are thought to play a major role in the dissolu- tion of the bone and cartilage matrix, allowing ...
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Effect of MMP-2 gene silencing on radiation-induced DNA damage in human normal dermal fibroblasts and breast cancer cells
... Matrix metalloproteinases are a broad family of Zn con- taining proteases including collagenases, gelatinases, stro- melysins, elastases and membrane-type ...[9]. Matrix ...
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Matrix metalloproteinases in inflammatory bowel disease : expression, regulation and clinical relevance
... of MMP-9 are also known to be chemotactic for inflammatory ...of MMP-9 mRNA in blood leukocytes in patients with ...the MMP-9 gene transcription through regulation of the nuclear factor (NF)-κB ...
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