MMP, matrix metalloproteinase
C-1562T polymorphism of matrix metalloproteinase-9 (MMP-9) gene associated with elevated level of plasma MMP-9 concentration in patient with acute myocardial infarction (AMI) in Denpasar-Bali
... occurred, MMP-9 also had an important role in ventricular ...of MMP-9 within myocardium increases the rate of fibrosis within the infracted and penumbral ...
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Immunohistochemical expression of Matrix Metalloproteinase-2 (MMP-2) in inguinal hernia
... extracellular matrix components predominantly collagen is controlled by an equilibrium between matrix metalloproteinases and their inhibitors (43) ...of matrix metalloproteinases are being ...
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Roles of low-density lipoprotein receptor-related protein 1 in tumors
... regulating matrix metalloproteinase (MMP)-2 and MMP-9 expression and functions but also inhibits cell apoptosis by regulating the insulin receptor, the serine/ threonine protein kinase ...
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The matrix metalloproteinase and insulin-like growth factor system in oral cancer – a prospective clinical study
... Results: Serum levels of MMP-3 were significantly higher in OSCC patients compared to healthy subjects (p=0.004). Mean IGF-1 and IGFBP-3 levels in OSCC patients were signifi- cantly lower in healthy subjects ...
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Original Article Serum levels of matrix metalloproteinase-2 and matrix metalloproteinase-9 have clinical significance for the evaluation of the prognosis of patients with ruptured intracranial aneurysms after interventional therapy
... angiospasm. MMP-2 and MMP-9 are mainly secreted by macroph- ages and ...abundant MMP-2 and MMP-9 ...of MMP-2 and MMP-9 under different Hunt-Hess grades and different cere- bral ...
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Adiponectin is a potential catabolic mediator in osteoarthritis cartilage
... of metalloproteinase (TIMP)-2 and downregulates IL-1b-induced matrix metalloproteinase (MMP)-13 in OA chondrocytes, whereas Lago et ...IL-6, MMP-3, MMP-9, and MCP-1 in murine ...
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Curcumin slows osteoarthritis progression and relieves osteoarthritis associated pain symptoms in a post traumatic osteoarthritis mouse model
... Background: Curcumin has been shown to have chondroprotective potential in vitro. However, its effect on disease and symptom modification in osteoarthritis (OA) is largely unknown. This study aimed to determine whether ...
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Fluid-induced, shear stress-regulated extracellular matrix and matrix metalloproteinase genes expression on human annulus fibrosus cells
... the MMP-1 and -3 genes was upregulated in rabbit tendon cells following 1 dyne/cm 2 fluid-induced shear stress for 6 h in a specially designed multi-slide flow device ...
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Synergistic and protective effect of atorvastatin and amygdalin against histopathological and biochemical alterations in Sprague-Dawley rats with experimental endometriosis
... Langendonckt et al. 2002; Giudice and Kao 2004). Ele- vated levels of matrix metalloproteinase-2 (MMP2) and MMP-9 have also been reported (Chung et al. 2001; Osteen et al. 2003). The treatment of ...
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Periodontitis and Rheumatoid Arthritis - The Dual Link
... of matrix metalloproteinase (MMP)- 8 and -13 and tissue inhibitor of MMP (TIMP)-1 in patients with rheumatoid arthritis (RA) and systemically healthy counterparts with inflammatory periodontal ...
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Matrix metalloproteinase 3 inhibitor retards treadmill running induced cartilage degradation in rats
... rat MMP-3 (1:50 dilution, Santa Cruz Biotechnology, Santa Cruz, CA, USA) for ...for MMP-3 in the joint cartilage was evaluated by calculating the ratio of the number of MMP-3 immunoreactive ...
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Original Article Association of MMPs/TIMPs polymorphism with alcohol-induced osteonecrosis of femoral head in the Chinese Han population
... Abstract: Alcohol-induced osteonecrosis of the femoral head (alcohol-induced ONFH) makes up almost one-third of the total proportion of non-traumatic ONFH. Polymorphism of matrix metalloproteinase ...
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Matrix metalloproteinase-2, tissue inhibitor of matrix metalloproteinase-2, and transforming growth factor beta 1 in the aqueous humor and serum of patients with pseudoexfoliation syndrome
... the control groups. This finding suggests that these molecules may not be major risk factors for the investigated disease, but they might be the outcomes. According to recent reports, increased oxidative stress and a ...
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Relationship between radiographic grading of osteoarthritis and the biochemical markers for arthritis in knee osteoarthritis
... plasma matrix metalloproteinase (MMP)-3, MMP-9 and tissue inhibitor of metalloproteinases (TIMP)-1 were measured as the biochemical markers of ...
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Transforming growth factor activating kinase 1 regulates extracellular matrix degrading enzymes and pain related molecule expression following tumor necrosis factor α stimulation of synovial cells: an in vitro study
... of matrix metalloproteinase-3 (MMP-3) and a disintegrin- like and metalloprotease (reprolysin type) with thrombos- pondin type 1 motif, ADAMTS-4 (aggrecanase 1) by OA synovial fibroblasts in mice ...
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Different Sensors Used for Biochemical Detection
... ABSTRACT:Biochemical process measurement shows great importance in our daily life. Mainly this paper describes to realize an efficient and proper working sensor to detect the biochemical process. Here we discuss about ...
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Original Article Matrix metalloproteinase-3 and -9: possible biomarkers of infliximab efficacy in ankylosing spondylitis (AS)?
... of MMP-9 was associated with ASDAS and declined with the improvement of ASDAS, which was similar with ...of MMP-9 is also associated with the disease activity in ...between MMP-3 and ...of ...
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Clinical evaluation of a matrix metalloproteinase 12 cleaved fragment of titin as a cardiovascular serological biomarker
... Extracellular matrix (ECM) components are degraded by a number of different proteases including matrix metalloproteinases ...(MMPs). MMP-degradation of pro- teins generates specific cleavage sites on ...
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Toll like receptor 2 (TLR2) induces migration and invasive mechanisms in rheumatoid arthritis
... Cell migration is essential for tissue infiltration during the inflammatory process and is initiated by cell polar- isation and the formation of membrane protrusions at the leading edge [12]. Integrin-linked activation ...
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Active synovial matrix metalloproteinase 2 is associated with radiographic erosions in patients with early synovitis
... lular matrix are thought to play a major role in the dissolu- tion of the bone and cartilage matrix, allowing the invasive cells to migrate into the stroma across cell ...each MMP to this process ...
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