(MnZn)Fe/sub 2/O/sub 4/
In vitro and in vivo targeting imaging of pancreatic cancer using a Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub> nanoprobe modified with anti-mesothelin antibody
... In this study, all the mice were successfully developed into subcutaneously transplanted tumor models. When the diam- eter of subcutaneously transplanted tumor reached 1.0 cm, nine mice were divided into three groups ...
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Immobilized transferrin Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub> nanoparticle with high doxorubicin loading for dual-targeted tumor drug delivery
... The procedures for generation and drug loading of TfDMP are shown in Figure 1. By coupling GA with amino- immobilized Fe 3 O 4 @SiO 2 , the surface of the magnetic nanoparticle can be modified ...
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Combination of PEI-Mn<sub>0.5</sub>Zn<sub>0.5</sub>Fe<sub>2</sub>O<sub>4</sub> nanoparticles and pHsp 70-<em>HSV</em>-<em>TK</em>/GCV with magnet-induced heating for treatment of hepatoma
... Signal transducer and activator of transcription 3 (Stat3) is one of the most important members of the signal transducer and activator of transcriptional family (which includes Stat1–4, Stat5a and Stat5b, and ...
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Biological responses to core–shell-structured Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub>-NH<sub>2</sub> nanoparticles in rats by a nuclear magnetic resonance-based metabonomic strategy
... All univariate statistical tests were two-sided, and sig- nificance was set at P,0.05. Multivariate statistical analysis can take internal relationships and mutual influence among variables into account; therefore, the ...
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Polyetherimide-grafted Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub> nanoparticles as theranostic agents for simultaneous VEGF siRNA delivery and magnetic resonance cell imaging
... (PEI)-modified Fe 3 O 4 @SiO 2 , which allows high efficient loading of VEGF small hairpin (sh)RNA to form Fe 3 O 4 @SiO 2 /PEI/VEGF shRNA nanocomposites for VEGF ...
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<p>Prostate Cancer Cellular Uptake of Ternary Titanate Nanotubes/CuFe<sub>2</sub>O<sub>4</sub>/Zn-Fe Mixed Metal Oxides Nanocomposite</p>
... Human prostate cancer PC-3 cell lines were obtained from the American-Type Culture Collection (ATCC, Rockville, MD). Mammalian cell lines: MRC-5 cells (Normal human Lung fi broblast cells) were acquired from VACSERA ...
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Biosafety evaluation of Janus Fe<sub>3</sub>O<sub>4</sub>-TiO<sub>2</sub> nanoparticles in Sprague Dawley rats after intravenous injection
... mg/kg Fe 3 O 4 -TiO 2 NP group, liver coefficients of rats were significantly higher than the control ...TiO 2 NP-treatment group. Other TiO 2 NP-treated animals also showed a ...
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Vancomycin-modified Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub>@Ag microflowers as effective antimicrobial agents
... 3 O 4 @SiO 2 @Ag microflower with enhanced antibacterial activity is experimentally and theoretically presented in this ...3 O 4 @SiO 2 @Ag microflowers can rapidly and ...
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Effects of magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> combinated with gambogic acid on apoptosis of SMMC-7721 cells
... that Fe 3 O 4 -MNP at less than 20 μ g/mL concen- tration had no obviously effect on SMMC-7721 prolif- eration ...g/mL Fe 3 O 4 -MNP with different con- centrations of GA to find ...
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The changes of T lymphocytes and cytokines in ICR mice fed with Fe<sub>3</sub>O<sub>4</sub> magnetic nanoparticles
... cells/mL with RPMI-1640. The adjusted cells were placed in a 96-well microtiter plate in 200 µ L aliquots and cultured in the presence of T-lymphocytes mitogen (5 µ g/mL Con- canavalin A [ConA]) (Sigma Chemical Co, St. ...
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Molecular study of wound healing after using biosynthesized BNC/Fe<sub>3</sub>O<sub>4</sub> nanocomposites assisted with a bioinformatics approach
... 3 O 4 was nontoxic (IC 50 ...3 O 4 has an effect on microRNA by reducing its expression and therefore causing an increase in the gene expression of other genes, which consequently resulted in ...
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Multifunctional magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles combined with chemotherapy and hyperthermia to overcome multidrug resistance
... Samples of tumor tissue weighing 0.1 g was collected from each mouse and homogenized for detection of P- glycoprotein, Bcl-2, Bax, and caspase-3. Briefly, the tissues were extracted with Triton X-100, and the ...
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In vitro toxicity of Fe<sub>m</sub>O<sub>n</sub>, Fe<sub>m</sub>O<sub>n</sub>-SiO<sub>2</sub> composite, and SiO<sub>2</sub>-Fe<sub>m</sub>O<sub>n</sub> core-shell magnetic nanoparticles
... uncoated, Fe m O n -SiO 2 composite flake-like, and SiO 2 -Fe m O n core-shell IONPs on cell viability, function, and mor- phology were tested 48 h postincubation in human ...
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Preparation and in vitro evaluation of doxorubicin-loaded Fe<sub>3</sub>O<sub>4</sub> magnetic nanoparticles modified with biocompatible copolymers
... 6H 2 O), ferrous chloride tetrahydrate (FeCl 2 ⋅ 4H 2 O), and ammonium hydroxide (25 wt%) were purchased from Fluka (Buchs, ...(Oct) 2 :stannous 2-ethylhexanoate), PEG ...
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Fe<sub>3</sub>O<sub>4</sub>/Au magnetic nanoparticle amplification strategies for ultrasensitive electrochemical immunoassay of alfa-fetoprotein
... Cyclic voltammetry measurements were performed using an electrochemical analyzer CHI 660 (Shanghai Chenhua Instrumental Corp, China) connected to a personal com- puter. A three-compartment electrochemical cell contained ...
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The reversal effect of magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles loaded with cisplatin on SKOV3/DDP ovarian carcinoma cells
... in 6-well plates were treated with one of the following treatments: (a) DDP + MNPs-Fe 3 O 4 , (b) DDP, (c) MNPs- Fe 3 O 4 , (d) RPMI-1640 for 48 h, and harvested. Cells were ...
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Effect of magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> and wogonin on the reversal of multidrug resistance in K562/A02 cell line
... TRIzol. 4 µg of total RNA was added to reverse transcriptase buffer, 25 mmol/L of MgCl 2 , 10 mmol/L deoxyribonucleotide triphosphates, random 9 mers (50 pmol/ µ L), RNase inhibitor (40 U/ µ L), and avian ...
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Inhibitory effect of magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles coloaded with homoharringtonine on human leukemia cells in vivo and in vitro
... were injected with 2.5 mg/kg HHT or HHT-MNP-Fe 3 O 4 . The treatment was carried out three times without interval in 3 days by the tail vein. Tumor volume was measured at days 7, 14, 21, and 28 to ...
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Ultrasmall superparamagnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles: honey-based green and facile synthesis and in vitro viability assay
... the Fe 3 O 4 -NPs are spherical with a diameter range between ...of Fe 3 O 4 -NPs performed by using the MTT assay on the WEHI164 cells demonstrated no significant toxicity in ...
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Co-encapsulation of magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles and doxorubicin into biodegradable PLGA nanocarriers for intratumoral drug delivery
... × 4 mm, 60 tumor-bearing mice were randomly assigned to one of the following six treatment groups (n = 10 per group): (1) DOX-MNPs (10 mg/kg, single dose) with an external magnetic field; (2) DOX-MNPs only ...
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